Companies: 10,795·Total market cap: $144.5T
Aprea Therapeutics, Inc.

Aprea Therapeutics, Inc.

APRENASDAQHealthcare● Active
$0.74
+$0.01(+0.79%)
Market Cap$4806596
P/E Ratio
52W High$2.22
52W Low$0.548

Aprea Therapeutics, Inc. (APRE) Free Cash Flow & Analysis

Annual & trailing free cash flow, FCF margin, YoY change, valuation ratios, and peer context.

APRE · free cash flow · updated Jun 9, 2026

Core FCF metrics

Free cash flow was −$12.9M for FY2025 (fiscal year ending 2025-12-31), up 5.0% year-over-year

FY2025 Free Cash Flow−$12.9M▲ +5.0% YoY
Trailing 12M (TTM)−$12.2Mtrailing 4 quarters sum
FCF Margin
3-Year CAGRN/AN/A — contains negative FCF
5-Year CAGRN/AN/A — contains negative FCF
FormulaFCF = Operating Cash Flow − Capital ExpendituresTTM = trailing 4 quarters sumCAGR → N/A if either endpoint ≤ 0
Source: FMP /cash-flow-statement · SEC 10-K / 10-Q · USDUpdated: Jun 9, 2026

Annual free cash flow history

Positive FCFNegative FCF
Free Cash Flow
YoY Growth %
apre free cash flow history · apre free cash flow chart · apre free cash flow growth rate · apre free cash flow last 10 years

Annual free cash flow data

Fiscal YearFree Cash FlowYoY ChangeFCF Margin
FY2025Latest−$12.9M▲ +5.0%
FY2024−$13.6M▼ 10.6%-903.3%
FY2023−$12.3M▲ +50.9%
FY2022−$25.0M▲ +33.6%
FY2021−$37.7M▲ +9.9%
FCF = Operating Cash Flow − Capital Expenditures · CapEx shown as (negative) · Source: SEC filings via FMP
apre free cash flow 2025 · apre free cash flow 2024 · apre free cash flow 2023 · apre operating cash flow

FCF valuation metrics

Aprea Therapeutics, Inc. (APRE) reported negative free cash flow of −$0.01B. FCF-based valuation ratios are not meaningful when FCF is negative.

FCF Yield (TTM)
N/A
Free Cash Flow ÷ Market Cap
per FMP freeCashFlowYieldTTM definition
FCF per Share (TTM)
N/A
TTM FCF ÷ Shares Outstanding
Price / FCF
N/A
Share Price ÷ FCF per Share
EV / FCF (TTM)
N/A
Enterprise Value basis
!

FCF-based valuation ratios are only meaningful when free cash flow is positive. Negative FCF indicates capital expenditures exceeded operating cash flow.

Source: FMP /key-metrics-ttm · /cash-flow-statement Q · /income-statementFY2025 · 2025-12-31
apre price to free cash flow · apre free cash flow yield · apre free cash flow per share · apre price to cash flow ratio

Cash flow statement summary

For FY2025, Aprea Therapeutics, Inc. generated −$12.9M in operating cash flow and spent 0M in capital expenditures, yielding −$12.9M in free cash flow.

Operating Activities
−$12.9M
Cash from core business operations
2025-12-31
Investing Activities
+$0.0M
CapEx, acquisitions & investments
2025-12-31
Financing Activities
+$4.6M
Buybacks, dividends & debt
2025-12-31
FCF FormulaOperating CF (−$12.9M) − |CapEx| (0M) = FCF (−$12.9M)

For the complete Operating / Investing / Financing line-item breakdown:

View Full Cash Flow Statement
apre cash flow statement · apre cash flow statement 2025 · apre operating cash flow · apre cash flow from operations

Free cash flow vs peers (Healthcare)

#CompanyFree Cash FlowYoY
#1
Aprea Therapeutics, Inc.
Aprea Therapeutics, Inc.YOU
APRE
−$12.9M+5.0%
#2
Johnson & Johnson
Johnson & Johnson
JNJ
$19.70B-0.7%
#3
AbbVie Inc.
AbbVie Inc.
ABBV
$17.82B-0.1%
#4
UnitedHealth Group Incorporated
UnitedHealth Group Incorporated
UNH
$16.07B-22.4%
#5
Eli Lilly and Company
Eli Lilly and Company
LLY
$8.97B+2065.6%
Healthcare · Sorted by FCF · FMP /cash-flow-statementFull FCF Rankings →

About Free Cash Flow & Methodology

Aprea Therapeutics, Inc. (APRE) reported free cash flow of −$12.9M for FY2025 (fiscal year ending 2025-12-31), up 5.0% year-over-year.

Aprea Therapeutics, Inc. has reported negative free cash flow in recent periods, indicating capital expenditures have exceeded operating cash flow. Data available for 9 fiscal years.

Data sourced from FMP /cash-flow-statement · SEC 10-K / 10-Q · USD.

Q&A and summaries align with SEC 10-K/10-Q cash flow disclosures and FMP /cash-flow-statement where noted.

Frequently asked questions

APRE free cash flow · 8 questions

Aprea Therapeutics, Inc. free cash flow was −$12.9M for FY2025, up 5.0% year-over-year. On a trailing twelve-month (TTM) basis, free cash flow stands at −$12.2M.

APRE free cash flowAPRE FCFAPRE FCF 2025APRE free cash flow TTM

Source: FMP /cash-flow-statement · US GAAP · Aprea Therapeutics, Inc. · Aprea Therapeutics, Inc. SEC 10-K & 10-Q filings · US GAAP · Last updated: Jun 9, 2026