Companies: 10,795·Total market cap: $144.5T
Karyopharm Therapeutics Inc.

Karyopharm Therapeutics Inc.

KPTINASDAQHealthcare● Active
$8.50
$-0.58(-6.39%)
Market Cap$192635016
P/E Ratio
52W High$10.99
52W Low$3.65

Karyopharm Therapeutics Inc. (KPTI) Stock Forecast & Analyst Price Target

Wall Street consensus, 12-month price targets, model projections, and EPS/revenue estimates — from analyst data and price history.

kpti · stock forecast · 20 analysts (3M) · FMP · updated Jun 9, 2026

Analyst Rating & Consensus

Based on 20 Wall Street analysts in the past 3 months

SellBuy

Buy

20 analysts

consensus

Rating Breakdown

Strong Buy
0
Buy
14
Hold
4
Sell
2
Strong Sell
0
Total: 20 · Buy rate: 70.0%

12-Month Price Target

High

$28.00

Consensus

$17.25

+102.9% upside

Low

$12.00

Median: $14.5 · Last Close: $8.50

The Karyopharm Therapeutics Inc. (KPTI) analyst consensus is Buy, based on ratings from 20 Wall Street analysts over the past 3 months. The average 12-month KPTI price target is $17.25, representing +102.9% upside from the current price of $8.50.

12-Month Price Target Forecast

Historical closing prices + analyst 12-month price target forecast cone

Historical priceConsensus $17 (102.9%)

Consensus Target

$17.25

102.9% upside

High Target

$28

229.4%

Low Target

$12

41.2%

Current Price

$8.50

as of today

Based on analyst price targets, the KPTI stock price prediction for the next 12 months ranges from $12 to $28. The consensus KPTI price forecast of $17.25 implies 102.9% upside from the current price of $8.50.

Short-Term Price Prediction

Algorithmically generated · Updated daily

DatePredicted PriceChange
2026-06-10$8.712.52%

1-day model range: $8.64–$8.79. Peak: $8.79 (+2.52%).

Long-Term Stock Price Prediction

Annual stock price forecast · 2027 / 2028 / 2029 / 2030 / 2031

YearAvg PriceChange
2027$4-50.0%
2028$3-62.5%
2029$3-67.2%
2030$3-69.2%
2031-70.2%
Confidence:Medium

Stock Forecast Based on Technical Analysis

14 TA signals (SMA×6 + EMA×6 + RSI + MACD) · EEAT method transparency

Market Sentiment

NEUTRAL

Based on 14 technical indicators

50%7%43%
7Buy
1Neutral
6Sell
RSI (14)66.3Neutral
MACDBULLISH

Refreshes daily from EOD close

Moving Averages · KPTI · Jun 9, 2026

Simple Moving Average (SMA)
MA 5$8.98SELL
MA 10$9.09SELL
MA 20$8.64SELL
MA 50$8.27BUY
MA 100$7.99BUY
MA 200$7.19BUY
Current $KPTI · Price above MA = BUY signal
Exponential Moving Average (EMA)
EMA 5$8.90SELL
EMA 10$8.90SELL
EMA 20$8.77SELL
EMA 50$8.45BUY
EMA 100$8.01BUY
EMA 200$7.62BUY
Current $KPTI · Price above MA = BUY signal
How we calculate: Technical sentiment is derived from 14 indicators — SMA(5,10,20,50,100,200), EMA(5,10,20,50,100,200), RSI(14), and MACD(12,26,9) — calculated from historical EOD price data. BUY = current price above MA; SELL = below. 14 TA signals + historical EOD price data · Updated daily. Independent of analyst consensus data. Not investment advice.

Latest Analyst Ratings & Upgrades

Filter:
HC Wainwright & Co.2026-05-06
Maintains
BuyBuy
Piper Sandler2026-04-27
Maintains
OverweightOverweight
Piper Sandler2026-03-30
Maintains
OverweightOverweight
HC Wainwright & Co.2026-03-25
Maintains
BuyBuy
Baird2026-03-25
Maintains
OutperformOutperform
HC Wainwright & Co.2026-02-18
Maintains
BuyBuy
RBC Capital2025-11-04
Maintains
OutperformOutperform
HC Wainwright & Co.2025-10-13
Upgrade ↑
NeutralBuy
Piper Sandler2025-10-09
Maintains
OverweightOverweight
Baird2025-10-09
Maintains
OutperformOutperform

Wall Street analysts have recently issued updated ratings on Karyopharm Therapeutics Inc. (KPTI) stock. Of the recent 129 rating actions, 9 were upgrades and 13 were downgrades. 20 analysts currently cover KPTI.

Analyst Recommendation Trends

Buy ratings312
Hold ratings00
Sell ratings00

KPTI analyst recommendation trends show decreasing buy-side sentiment over the past 6 months. Buy rating actions changed from 3 to 1 per month.

Financial Forecast: EPS & Revenue Estimates

Revenue This Year

$137M

↓ 40.4% YoY

Revenue Next Year

$155M

↑ 13.2% YoY

EPS This Year

$-4.08

EPS Next Year

$-3.12

↓ 23.5% YoY

EPS ForecastReported vs Estimated

Reported EPSHistorical estimateAnalyst forecast (future)

Analysts forecast KPTI EPS of $-4.08 for the current fiscal year, based on estimates from 3 analysts. The KPTI revenue forecast is $137M for the current year. These are analyst consensus estimates via FMP / S&P Global.

About Forecast & Price Prediction

The KPTI stock forecast is supported by two independent data sources: analyst consensus ratings from 20 Wall Street analysts (S&P Global / FMP), and technical analysis calculated from historical EOD price data. The consensus KPTI price target is $17.25 (+102.9% upside), with an analyst consensus of Buy.

The KPTI short-term stock prediction for tomorrow is $8.71 (+2.52%). The KPTI stock price prediction for 2027 estimates an average of $4. The KPTI stock prediction for 2030 projects a range of $2–$3.

Karyopharm Therapeutics Inc. trades on NASDAQ under the ticker KPTI. The KPTI stock outlook for 2027 is broadly positive, supported by a Buy consensus among 70% of covering analysts.

FAQ answers synthesize analyst targets, estimates, and on-page model outputs where shown.

Frequently asked questions

KPTI forecast · 8 questions

According to 20 Wall Street analysts, the average 12-month KPTI price target is $17.25, with a high forecast of $28.00 and a low of $12.00. The median price target is shown in the chart above when available. This implies +102.9% potential upside from the current price of $8.50.

KPTI price targetWhat is KPTI price targetKPTI analyst price targetKPTI 12-month target

· Analyst data: Financial Modeling Prep (FMP) · S&P Global Market Intelligence · Technical analysis: FMP /historical-price-eod/light · Updated: Hourly (analyst) · Daily (technical)

⚠ This information is provided for informational purposes only and does not constitute investment advice. Short-term and long-term price predictions are algorithmically generated and carry significant uncertainty. Past performance does not guarantee future results. Always conduct your own due diligence before making investment decisions.