Companies: 10,795·Total market cap: $144.5T
Puma Biotechnology, Inc.

Puma Biotechnology, Inc.

PBYINASDAQHealthcare● Active
$6.85
$-0.18(-2.56%)
Market Cap$348661274
P/E Ratio
52W High$7.9
52W Low$3.03

Puma Biotechnology, Inc. (PBYI) PE Ratio — Current & Historical Data

Trailing twelve months (TTM) P/E, forward P/E, PEG, and annual PE history — from market prices and filings.

pbyi · pe ratio · data through Dec 31, 2025

Core PE Ratio Metrics

Trailing 12 months · TTM

The price-to-earnings (P/E) ratio for Puma Biotechnology, Inc. (PBYI) measures how much investors pay for each dollar of the company's trailing earnings. PBYI's current PE ratio of 14.28x is calculated by dividing its stock price of $6.85 by its TTM earnings per share of $0.48. +79.2% elevated vs 5Y avg 8.0x

14.28x
P/E Ratio (TTM)+79.2%

Source: FMP · /ratios-ttm · /analyst-estimates · 2025-12-31

Forward P/E
34.25x
FY2027 est. EPS $0.20
Based on 1 analyst
EPS (TTM)
$0.48
TTM · diluted EPS
PEG Ratio
-0.41
Source: FMP · /ratios-ttm · /ratios annual · /analyst-estimates · /stock-peers · Puma Biotechnology, Inc. SEC 10-K & 10-Q filings · US GAAPUpdated: 2026-06-09

PE Ratio History

2007 – 2025 · Annual
PE Ratio (TTM)
5Y Avg 8.0x
EPS (Annual)

▸ FMP /ratios?period=annual&limit=20 · priceToEarningsRatio + netIncomePerShare (Annual)

Historical PE Range

Past 3 fiscal years · Front-end computed
Average
8.0x
3-yr mean
Median
9.5x
3-yr midpoint
Minimum
4.9x
Lowest year
Maximum
9.6x
Highest year
14.3x ← Now
4.9x
Min
Q1 · 25%9.5x
Median
Q3 · 75%9.6x
Max
Historically Elevated

At 14.28x, PBYI's current P/E is higher than in 100% of its annual fiscal year readings over the past 3 years — historically elevated.

100th percentileHigher than 3 of 3 historical fiscal year readings

Percentile calculated from annual fiscal year data points, not by trading day. Years where PE ≤ 0 or > 9,999 are excluded.

PE Ratio vs Peers

Biotechnology · 6 peers · Annual PE
CompanyMarket CapPE (Annual)vs AvgEPS (TTM)
Puma Biotechnology, Inc.
Puma Biotechnology, Inc.You
PBYI
$349M14.28x$0.48
Abeona Therapeutics Inc.
Abeona Therapeutics Inc.
ABEO
$307M3.92x$1.34
Allogene Therapeutics, Inc.
Allogene Therapeutics, Inc.
ALLO
$451MN/A-$0.87
Arcturus Therapeutics Holdings Inc.
Arcturus Therapeutics Holdings Inc.
ARCT
$202MN/A-$2.40
Atea Pharmaceuticals, Inc.
Atea Pharmaceuticals, Inc.
AVIR
$346MN/A-$1.94
Eledon Pharmaceuticals, Inc.
Eledon Pharmaceuticals, Inc.
ELDN
$215MN/A-$0.56
Humacyte, Inc.
Humacyte, Inc.
HUMA
$232MN/A-$0.26

* N/A — Company is not profitable (TTM) · excluded from industry average · ▸ FMP /stock-peers + /ratios?limit=1 · priceToEarningsRatio

Annual PE Ratio History

Showing 10 of 19 years
Fiscal Year EndPE RatioEPS (TTM)YoY ChangePE vs Max
2025-12-31Latest
FY2025
9.56x$0.62+95.2%
2024-12-31
FY2024
4.90x$0.62-48.2%
2023-12-31
FY2023
9.45x$0.46-100.0%
2022-12-31
FY2022
$0.00
2021-12-31
FY2021
$-0.72
2020-12-31
FY2020
$-1.52
2019-12-31
FY2019
$-1.95
2018-12-31
FY2018
$-2.99
2017-12-31
FY2017
$-7.86
2016-12-31
FY2016
$-8.29

▸ FMP /ratios?period=annual&limit=20 · priceToEarningsRatio + netIncomePerShare · Zero extra API

About PE Ratio & Methodology

The price-to-earnings (P/E) ratio for Puma Biotechnology, Inc. (PBYI) measures how much investors pay for each dollar of the company's trailing earnings. PBYI's current PE ratio of 14.28x is calculated by dividing its stock price of $6.85 by its TTM earnings per share of $0.48.

PE Ratio = Stock Price ÷ EPS (TTM)
= $6.85 ÷ $0.48 = 14.28x
TTMTrailing Twelve Months — sum of the most recent 4 quarterly EPS figures
Forward PEStock price ÷ analyst consensus EPS estimate for the next fiscal year
PEGPE ÷ earnings growth rate — values below 1.0 suggest growth may justify the premium
Figures tie to SEC 10-K/10-Q and FMP ratio endpoints where noted.

Frequently asked questions

PBYI pe ratio · 6 questions

PBYI's current PE ratio is 14.28x as of 2026-06-09, based on a stock price of $6.85 and TTM EPS of $0.48. Data sourced from Financial Modeling Prep via PBYI's SEC 10-K and 10-Q filings.

PBYI PE ratioWhat is PBYI PE ratioCurrent PE ratio of PBYIPBYI PE ratio today

Source: FMP · /ratios-ttm · /ratios annual · /analyst-estimates · /stock-peers · Puma Biotechnology, Inc. SEC 10-K & 10-Q filings · US GAAP · Updated: 2026-06-09