
ProQR Therapeutics N.V.
ProQR Therapeutics N.V. (PRQR) Stock Ownership
Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.
SEC 13F · FMP · PRQR · as of Sep 30, 2025
Ownership Breakdown
64
Institutional Holders
$79.97M
Total Inst. Value
▼ $2.42M vs Q2
105.36M
Shares Outstanding
freeFloat 61.07%
37.54M
13F Shares Held
▼ 2.92M vs Q2
Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.
Top Institutional Holders
PRQR largest shareholders · institutional ownership
Q3 2025 · SEC 13F
Showing top 10 holders
| Holder | Shares | % Owned | Weight | Value | Reported | Change |
|---|---|---|---|---|---|---|
ADAGE CAPITAL PARTNERS GP, L.L.C. pharmaceutical preparations | 6.25M | 5.94% | 5.94% | $13.32B | Nov 14, 2025 | ▼ 348.5K |
PRIVIUM FUND MANAGEMENT B.V. pharmaceutical preparations | 5.00M | 4.74% | 4.74% | $10.65B | Nov 4, 2025 | ▲ 725 |
AFFINITY ASSET ADVISORS, LLC pharmaceutical preparations | 3.60M | 3.42% | 3.42% | $7.67B | Nov 13, 2025 | ▲ 100.5K |
MORGAN STANLEY pharmaceutical preparations | 2.90M | 2.75% | 2.75% | $6.18B | May 27, 2026 | ▼ 182.3K |
ABRDN PLC pharmaceutical preparations | 2.30M | 2.18% | 2.18% | $4.90B | Nov 7, 2025 | ▲ 448.5K |
SIO CAPITAL MANAGEMENT, LLC pharmaceutical preparations | 2.08M | 1.97% | 1.97% | $4.42B | Nov 13, 2025 | — held |
KYNAM CAPITAL MANAGEMENT, LP pharmaceutical preparations | 1.65M | 1.57% | 1.57% | $3.51B | Nov 14, 2025 | — held |
DAFNA CAPITAL MANAGEMENT LLC pharmaceutical preparations | 1.57M | 1.49% | 1.49% | $3.34B | Nov 14, 2025 | — held |
SIREN, L.L.C. pharmaceutical preparations | 1.55M | 1.47% | 1.47% | $3.31B | Nov 13, 2025 | — held |
ARROWMARK COLORADO HOLDINGS LLC pharmaceutical preparations | 1.25M | 1.18% | 1.18% | $2.65B | Nov 14, 2025 | ▲ 46.6K |
Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).
Institutional Activity
Q3 2025 vs prior quarter
Q3 2025
16
Increased
+1.35M shares4
New Positions
first time holders9
Decreased
−4.40M shares0
Sold Out
fully exitedNet shares change (top 50)
3.05M
+1.35M / −4.40M
Net new holders
+11
4 new / 0 exited
Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).
Insider Buying vs Selling
PRQR insider trading · insider activity
Source: SEC Form 4
0
Buy transactions
0
Sell transactions
0.00
Buy/Sell ratio
$0M
Total disposed
Recent Insider Transactions
Showing 10 most recent · Common Stock only
No recent insider transactions reported.
Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.
About institutional & insider ownership
ProQR Therapeutics N.V. (PRQR) is primarily owned by institutional investors, who hold approximately 35.6% of total shares outstanding. Company insiders own approximately 38.93%, while retail and public investors account for the remaining 25.44%.
The largest institutional shareholder of ProQR Therapeutics N.V. is ADAGE CAPITAL PARTNERS GP, L.L.C., holding approximately 6.25 million shares — equal to 5.94% of outstanding shares — as of September 30, 2025.
A total of 64 institutional investors currently hold PRQR stock, with a combined institutional value of approximately $79,967,133 as of the most recent 13F filing period.
Frequently asked questions
PRQR ownershipProQR Therapeutics N.V. (PRQR) is primarily owned by institutional investors, who hold approximately 35.6% of shares. The largest shareholder is ADAGE CAPITAL PARTNERS GP, L.L.C. with a 5.94% stake. Company insiders hold 38.93%. Data sourced from SEC Form 13F as of September 30, 2025.