Reneo Pharmaceuticals, Inc.

RPHMNASDAQHealthcare

$18.20

+$16.47(+952.02%)

Market Cap$60840416

P/E Ratio—

52W High$82.9

52W Low$1.68

Avg Volume17K

Open$1.68

Beta0.22

Insider Trades Ownership Employees

Reneo Pharmaceuticals, Inc. (RPHM) Insider Trading

Form 4 buy vs sell counts, ratio, and sentiment — switch this quarter or last 12 months; chart and transactions below.

SEC EDGAR · FMP · RPHM · as of Jun 9, 2026

Activity summary

Buy transactions

P-Purchase only

Sell transactions

12 Months

Buy/Sell ratio

6.00

Buy/Sell (by trades)

Overall sentiment

BULLISH

↑ Buy 86%Active transactions only · RSU vesting excluded14% Sell ↓

Reneo Pharmaceuticals, Inc. insiders have been net buyers of shares over the past 12 Months, which may signal confidence in the company's outlook.

▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · Buy = P-Purchase only · Sell = S-Sale only

As of Jun 9, 2026

RPHM insider buying and selling by quarter

RPHM insider selling · RPHM insider buying stocks · quarterly insider activity

Total insider buying (incl. awards)Total insider selling

785K393K0

2022 Q1

2022 Q2

2022 Q3

2022 Q4

2023 Q2

2023 Q3

2024 Q2

2024 Q3

Mobile shows last 4Q · Desktop shows full 8Q

▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · last 8 quarters

As of Jun 9, 2026

Recent insider transactions

RPHM executive sell shares · RPHM board member insider trading · RPHM insider trading SEC filing

Showing 48 most recent · Common Stock · Form 4 only

Scroll horizontally to see all columns

Date	Insider	Type	Shares	Price	Value	After trans.	Filing
Sep 25, 2024	Leonard Braden Michael 10 percent owner	Purchase	68,746	$1.50	$103K	3,457,395	Form 4
Sep 24, 2024	Leonard Braden Michael 10 percent owner	Purchase	29,600	$1.41	$42K	3,388,649	Form 4
Sep 18, 2024	Leonard Braden Michael 10 percent owner	Purchase	806	$1.40	$1K	3,359,049	Form 4
Sep 17, 2024	Leonard Braden Michael 10 percent owner	Purchase	55,300	$1.36	$75K	3,358,243	Form 4
Sep 16, 2024	Leonard Braden Michael 10 percent owner	Purchase	172,747	$1.37	$237K	3,302,943	Form 4
Sep 13, 2024	Leonard Braden Michael 10 percent owner	Purchase	150,000	$1.31	$197K	3,130,196	Form 4
Sep 12, 2024	Leonard Braden Michael 10 percent owner	Purchase	36,176	$1.40	$51K	2,980,196	Form 4
Aug 14, 2024	Leonard Braden Michael 10 percent owner	Purchase	100,487	$1.41	$142K	2,944,020	Form 4
Aug 13, 2024	Leonard Braden Michael 10 percent owner	Purchase	171,339	$1.39	$239K	2,843,533	Form 4
May 14, 2024	Leonard Braden Michael 10 percent owner	Purchase	335,000	$1.54	$516K	2,672,194	Form 4
May 14, 2024	Leonard Braden Michael 10 percent owner	Purchase	79,281	$1.56	$124K	2,337,194	Form 4
Aug 28, 2023	Hall Ashley Chief Development Officer	Option	15,625	$1.80	$28K	55,225	Form 4
Aug 28, 2023	Hall Ashley Chief Development Officer	Sale	15,625	$6.28	$98K	39,600	Form 4
Jul 26, 2023	GREY MICHAEL G Executive Chairman · Director	Gift	50,000	—	—	0	Form 4
Jun 23, 2023	Novo Holdings A/S 10 percent owner	Sale	100,000	$7.10	$710K	3,330,337	Form 4
May 8, 2023	O'Donnell Niall Director	Purchase	125,000	$8.00	$1.00M⚡	2,188,713	Form 4
Aug 12, 2022	Dorenbaum Alejandro Chief Medical Officer	Gift	22,348	—	—	30,000	Form 4
Sep 1, 2022	Cruse Michael COO	Purchase	7,500	$3.39	$25K	13,697	Form 4
Aug 31, 2022	GREY MICHAEL G Executive Chairman · Director	Option	50,000	$1.97	$99K	50,000	Form 4
Aug 29, 2022	Cruse Michael COO	Purchase	3,212	$3.21	$10K	6,197	Form 4
Dec 10, 2021	Jindal Vineet R. CFO	Award	30,000	—	—	36,600	Form 4
Dec 10, 2021	FLESHER GREGORY J. President and CEO · Director	Award	100,000	—	—	109,600	Form 4
Dec 10, 2021	Dorenbaum Alejandro Chief Medical Officer	Award	30,000	—	—	52,348	Form 4
Dec 10, 2021	Cruse Michael Senior VP-Corporate Operations	Award	25,000	—	—	29,100	Form 4
Nov 12, 2021	Hall Ashley Chief Development Officer	Award	30,000	—	—	30,000	Form 4

Leonard Braden Michael

10 percent owner

Purchase

Date

Sep 25

68,746

Price

$1.50

Value

$103K

View Form 4 on SEC.gov

Leonard Braden Michael

10 percent owner

Purchase

Date

Sep 24

29,600

Price

$1.41

Value

$42K

View Form 4 on SEC.gov

Leonard Braden Michael

10 percent owner

Purchase

Date

Sep 18

806

Price

$1.40

Value

$1K

View Form 4 on SEC.gov

Leonard Braden Michael

10 percent owner

Purchase

Date

Sep 17

55,300

Price

$1.36

Value

$75K

View Form 4 on SEC.gov

Leonard Braden Michael

10 percent owner

Purchase

Date

Sep 16

172,747

Price

$1.37

Value

$237K

View Form 4 on SEC.gov

Leonard Braden Michael

10 percent owner

Purchase

Date

Sep 13

150,000

Price

$1.31

Value

$197K

View Form 4 on SEC.gov

Leonard Braden Michael

10 percent owner

Purchase

Date

Sep 12

36,176

Price

$1.40

Value

$51K

View Form 4 on SEC.gov

Leonard Braden Michael

10 percent owner

Purchase

Date

Aug 14

100,487

Price

$1.41

Value

$142K

View Form 4 on SEC.gov

Leonard Braden Michael

10 percent owner

Purchase

Date

Aug 13

171,339

Price

$1.39

Value

$239K

View Form 4 on SEC.gov

Leonard Braden Michael

10 percent owner

Purchase

Date

May 14

335,000

Price

$1.54

Value

$516K

View Form 4 on SEC.gov

Leonard Braden Michael

10 percent owner

Purchase

Date

May 14

79,281

Price

$1.56

Value

$124K

View Form 4 on SEC.gov

Hall Ashley

Chief Development Officer

Option

Date

Aug 28

15,625

Price

$1.80

Value

$28K

View Form 4 on SEC.gov

Hall Ashley

Chief Development Officer

Sale

Date

Aug 28

15,625

Price

$6.28

Value

$98K

View Form 4 on SEC.gov

GREY MICHAEL G

Executive Chairman · Director

Gift

Date

Jul 26

50,000

Price

—

Value

—

View Form 4 on SEC.gov

Novo Holdings A/S

10 percent owner

Sale

Date

Jun 23

100,000

Price

$7.10

Value

$710K

View Form 4 on SEC.gov

O'Donnell Niall

Director

Purchase

Date

May 8

125,000

Price

$8.00

Value

$1.00M ⚡

View Form 4 on SEC.gov

Dorenbaum Alejandro

Chief Medical Officer

Gift

Date

Aug 12

22,348

Price

—

Value

—

View Form 4 on SEC.gov

Cruse Michael

COO

Purchase

Date

Sep 1

7,500

Price

$3.39

Value

$25K

View Form 4 on SEC.gov

GREY MICHAEL G

Executive Chairman · Director

Option

Date

Aug 31

50,000

Price

$1.97

Value

$99K

View Form 4 on SEC.gov

Cruse Michael

COO

Purchase

Date

Aug 29

3,212

Price

$3.21

Value

$10K

View Form 4 on SEC.gov

Jindal Vineet R.

CFO

Award

Date

Dec 10

30,000

Price

—

Value

—

View Form 4 on SEC.gov

FLESHER GREGORY J.

President and CEO · Director

Award

Date

Dec 10

100,000

Price

—

Value

—

View Form 4 on SEC.gov

Dorenbaum Alejandro

Chief Medical Officer

Award

Date

Dec 10

30,000

Price

—

Value

—

View Form 4 on SEC.gov

Cruse Michael

Senior VP-Corporate Operations

Award

Date

Dec 10

25,000

Price

—

Value

—

View Form 4 on SEC.gov

Hall Ashley

Chief Development Officer

Award

Date

Nov 12

30,000

Price

—

Value

—

View Form 4 on SEC.gov

⚡ = value ≥ $1M · Award/Option price shows — · formType=4 · securityName=Common Stock · url → sec.gov/Archives/edgar

1 / 2

▸ Source: SEC EDGAR · Form 4 filings · ⚡ = value ≥ $1M · Award/Option price shows —

About RPHM insider trading

RPHM insider trades

Reneo Pharmaceuticals, Inc. (RPHM) insider trading data is sourced from SEC Form 4 filings submitted by corporate insiders, including RPHM. Over the past 12 months, 0 insiders have filed transactions with the SEC. RPHM insiders have been primarily buying, which may reflect pre-scheduled Rule 10b5-1 plan executions.

For Reneo Pharmaceuticals, Inc.'s institutional ownership breakdown and insider ownership percentage, see the Ownership tab → Ownership tab →

Buy/Sell signal logic

acquisitionOrDisposition field:

A = Acquisition (buy) · D = Disposition (sell)

RSU vesting (M-Exempt) excluded from sentiment

Form 4SEC filing required within 2 business days of any insider transaction

10b5-1Pre-scheduled trading plan that allows insiders to sell on autopilot

Open MktDirect purchase or sale on the open market (excludes awards, options)

Ownership SEC filings Financial statements Price history Forecast & ratings Earnings

Frequently asked questions

RPHM insider trading · 5 questions

The insiders of Reneo Pharmaceuticals, Inc. (RPHM) include executives and directors such as RPHM, among others. Over the past 12 months, 0 insiders have filed Form 4 transactions with the SEC. Insider transactions are required to be reported within 2 business days of the trade date.

RPHM board member insider tradingwho are RPHM insidersRPHM insider rosterReneo Pharmaceuticals, Inc. executives insider activity

▸ Source: FMP /stable/insider-trading/search · SEC EDGAR Form 3 & 4 · acquisitionOrDisposition A=Buy, D=Sell · RSU vesting (M-Exempt) excluded from sentiment bar · As of Jun 9, 2026