Spruce Biosciences, Inc.
Spruce Biosciences, Inc. (SPRB) PE Ratio — Current & Historical Data
Trailing twelve months (TTM) P/E, forward P/E, PEG, and annual PE history — from market prices and filings.
sprb · pe ratio · data through Dec 31, 2025
Core PE Ratio Metrics
Trailing 12 months · TTMThe price-to-earnings (P/E) ratio for Spruce Biosciences, Inc. (SPRB) measures how much investors pay for each dollar of the company's trailing earnings. SPRB's current PE ratio of N/A is calculated by dividing its stock price of $49.32 by its TTM earnings per share of -$27.11.
Source: FMP · /ratios-ttm · /analyst-estimates · 2025-12-31
PE Ratio History
2018 – 2025 · Annual▸ FMP /ratios?period=annual&limit=20 · priceToEarningsRatio + netIncomePerShare (Annual)
PE Ratio vs Peers
Biotechnology · 6 peers · Annual PE| Company | Market Cap | PE (Annual) | vs Avg | EPS (TTM) |
|---|---|---|---|---|
Spruce Biosciences, Inc.You SPRB | $68M | N/A | — | -$27.11 |
 Coeptis Therapeutics, Inc. COEP | $58M | N/A | — | -$2.81 |
 Cue Biopharma, Inc. CUE | $76M | N/A | — | -$8.42 |
 Equillium, Inc. EQ | $98M | N/A | — | -$0.24 |
 Werewolf Therapeutics, Inc. HOWL | $19M | N/A | — | -$1.32 |
 IO Biotech, Inc. IOBT | $1M | N/A | — | -$1.45 |
 NRx Pharmaceuticals, Inc. NRXP | $75M | N/A | — | -$1.34 |
* N/A — Company is not profitable (TTM) · excluded from industry average · ▸ FMP /stock-peers + /ratios?limit=1 · priceToEarningsRatio
Annual PE Ratio History
| Fiscal Year End | PE Ratio | EPS (TTM) | YoY Change | PE vs Max |
|---|---|---|---|---|
2025-12-31Latest FY2025 | — | $-50.83 | — | |
2024-12-31 FY2024 | — | $-98.87 | — | |
2023-12-31 FY2023 | — | $-95.72 | — | |
2022-12-31 FY2022 | — | $-75.49 | — | |
2021-12-31 FY2021 | — | $-69.63 | — | |
2020-12-31 FY2020 | — | $-48.84 | — | |
2019-12-31 FY2019 | — | $-22.87 | — | |
2018-12-31 FY2018 | — | $-496.01 | — |
▸ FMP /ratios?period=annual&limit=20 · priceToEarningsRatio + netIncomePerShare · Zero extra API
About PE Ratio & Methodology
The price-to-earnings (P/E) ratio for Spruce Biosciences, Inc. (SPRB) measures how much investors pay for each dollar of the company's trailing earnings. SPRB's current PE ratio of N/A is calculated by dividing its stock price of $49.32 by its TTM earnings per share of -$27.11.
Frequently asked questions
SPRB pe ratio · 6 questionsSPRB's current PE ratio is N/A as of 2026-06-09, based on a stock price of $49.32 and TTM EPS of -$27.11. Data sourced from Financial Modeling Prep via SPRB's SEC 10-K and 10-Q filings.
▸ Source: FMP · /ratios-ttm · /ratios annual · /analyst-estimates · /stock-peers · Spruce Biosciences, Inc. SEC 10-K & 10-Q filings · US GAAP · Updated: 2026-06-09