Companies: 10,795·Total market cap: $144.5T
Spero Therapeutics, Inc.

Spero Therapeutics, Inc.

SPRONASDAQHealthcare● Active
$2.74
$-0.08(-2.84%)
Market Cap$158650091
P/E Ratio
52W High$3.22
52W Low$1.8

Spero Therapeutics, Inc. (SPRO) Stock Forecast & Analyst Price Target

Wall Street consensus, 12-month price targets, model projections, and EPS/revenue estimates — from analyst data and price history.

spro · stock forecast · 13 analysts (3M) · FMP · updated Jun 9, 2026

Analyst Rating & Consensus

Based on 13 Wall Street analysts in the past 3 months

SellBuy

Buy

13 analysts

consensus

Rating Breakdown

Strong Buy
0
Buy
6
Hold
5
Sell
2
Strong Sell
0
Total: 13 · Buy rate: 46.2%

12-Month Price Target

High

$0.00

Consensus

$0.00

+0.0% upside

Low

$0.00

Median: $0 · Last Close: $2.74

The Spero Therapeutics, Inc. (SPRO) analyst consensus is Buy, based on ratings from 13 Wall Street analysts over the past 3 months. The average 12-month SPRO price target is $0.00, representing +0.0% upside from the current price of $2.74.

Short-Term Price Prediction

Algorithmically generated · Updated daily

DatePredicted PriceChange
2026-06-10$2.802.23%

1-day model range: $2.78–$2.82. Peak: $2.82 (+2.23%).

Long-Term Stock Price Prediction

Annual stock price forecast · 2027 / 2028 / 2029 / 2030 / 2031

YearAvg PriceChange
2027$3+20.2%
2028$4+32.3%
2029$4+39.0%
2030$4+42.5%
2031+44.3%
Confidence:Medium

Stock Forecast Based on Technical Analysis

14 TA signals (SMA×6 + EMA×6 + RSI + MACD) · EEAT method transparency

Market Sentiment

NEUTRAL

Based on 14 technical indicators

50%7%43%
7Buy
1Neutral
6Sell
RSI (14)58.9Neutral
MACDBULLISH

Refreshes daily from EOD close

Moving Averages · SPRO · Jun 9, 2026

Simple Moving Average (SMA)
MA 5$2.83SELL
MA 10$2.85SELL
MA 20$2.74SELL
MA 50$2.66BUY
MA 100$2.51BUY
MA 200$2.37BUY
Current $SPRO · Price above MA = BUY signal
Exponential Moving Average (EMA)
EMA 5$2.82SELL
EMA 10$2.81SELL
EMA 20$2.76SELL
EMA 50$2.66BUY
EMA 100$2.57BUY
EMA 200$2.48BUY
Current $SPRO · Price above MA = BUY signal
How we calculate: Technical sentiment is derived from 14 indicators — SMA(5,10,20,50,100,200), EMA(5,10,20,50,100,200), RSI(14), and MACD(12,26,9) — calculated from historical EOD price data. BUY = current price above MA; SELL = below. 14 TA signals + historical EOD price data · Updated daily. Independent of analyst consensus data. Not investment advice.

Latest Analyst Ratings & Upgrades

Filter:
HC Wainwright & Co.2025-01-30
Maintains
BuyBuy
Evercore ISI Group2024-12-20
Downgrade ↓
OutperformIn Line
HC Wainwright & Co.2024-12-02
Maintains
BuyBuy
TD Cowen2024-11-18
Downgrade ↓
BuyHold
HC Wainwright & Co.2024-11-04
Maintains
BuyBuy
HC Wainwright & Co.2024-10-03
Maintains
BuyBuy
HC Wainwright & Co.2024-08-06
Maintains
BuyBuy
TD Cowen2024-08-06
Upgrade ↑
HoldBuy
HC Wainwright & Co.2024-05-16
Maintains
BuyBuy
HC Wainwright & Co.2024-03-18
Maintains
BuyBuy

Wall Street analysts have recently issued updated ratings on Spero Therapeutics, Inc. (SPRO) stock. Of the recent 43 rating actions, 2 were upgrades and 8 were downgrades. 13 analysts currently cover SPRO.

Analyst Recommendation Trends

Buy ratings11
Hold ratings00
Sell ratings00

SPRO analyst recommendation trends show stable buy-side sentiment over the past 6 months. Buy rating actions changed from 1 to 1 per month.

Financial Forecast: EPS & Revenue Estimates

Revenue This Year

$26M

↑ 696.9% YoY

Revenue Next Year

$1M

↓ 96.9% YoY

EPS This Year

$-0.10

EPS Next Year

$0.67

↓ 770.0% YoY

EPS ForecastReported vs Estimated

Reported EPSHistorical estimateAnalyst forecast (future)

Analysts forecast SPRO EPS of $-0.10 for the current fiscal year, based on estimates from 1 analysts. The SPRO revenue forecast is $26M for the current year. These are analyst consensus estimates via FMP / S&P Global.

About Forecast & Price Prediction

The SPRO stock forecast is supported by two independent data sources: analyst consensus ratings from 13 Wall Street analysts (S&P Global / FMP), and technical analysis calculated from historical EOD price data. The consensus SPRO price target is $0.00 (+0.0% upside), with an analyst consensus of Buy.

The SPRO short-term stock prediction for tomorrow is $2.80 (+2.23%). The SPRO stock price prediction for 2027 estimates an average of $3. The SPRO stock prediction for 2030 projects a range of $4–$4.

Spero Therapeutics, Inc. trades on NASDAQ under the ticker SPRO. The SPRO stock outlook for 2027 is broadly positive, supported by a Buy consensus among 46% of covering analysts.

FAQ answers synthesize analyst targets, estimates, and on-page model outputs where shown.

Frequently asked questions

SPRO forecast · 8 questions

According to 13 Wall Street analysts, the average 12-month SPRO price target is $0.00, with a high forecast of $0.00 and a low of $0.00. The median price target is shown in the chart above when available. This implies +0.0% potential upside from the current price of $2.74.

SPRO price targetWhat is SPRO price targetSPRO analyst price targetSPRO 12-month target

· Analyst data: Financial Modeling Prep (FMP) · S&P Global Market Intelligence · Technical analysis: FMP /historical-price-eod/light · Updated: Hourly (analyst) · Daily (technical)

⚠ This information is provided for informational purposes only and does not constitute investment advice. Short-term and long-term price predictions are algorithmically generated and carry significant uncertainty. Past performance does not guarantee future results. Always conduct your own due diligence before making investment decisions.