Denali Therapeutics Inc.
Denali Therapeutics Inc. (DNLI) Insider Trading
Form 4 buy vs sell counts, ratio, and sentiment — switch this quarter or last 12 months; chart and transactions below.
SEC EDGAR · FMP · DNLI · as of Jun 8, 2026
Activity summary
Buy transactions
2
P-Purchase only
Sell transactions
6
12 Months
Buy/Sell ratio
0.33
Buy/Sell (by trades)
Overall sentiment
Denali Therapeutics Inc. insiders have been primarily selling shares over the past 12 Months. Selling activity is often driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment toward the company.
▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · Buy = P-Purchase only · Sell = S-Sale only
As of Jun 8, 2026
DNLI insider buying and selling by quarter
DNLI insider selling · DNLI insider buying stocks · quarterly insider activity
Mobile shows last 4Q · Desktop shows full 8Q
▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · last 8 quarters
As of Jun 8, 2026
Active insiders
Most active in past 12 months · DNLI ceo insider trading
Showing all insiders · Click a card to filter the transactions table below
▸ Aggregated from reportingName · top 5 by trade count (12M) · no extra API
Recent insider transactions
DNLI executive sell shares · DNLI board member insider trading · DNLI insider trading SEC filing
Scroll horizontally to see all columns
| Date | Insider | Type | Shares | Value | Filing |
|---|---|---|---|---|---|
| Jun 3, 2026 | FLATLEY JAY T Director | Award | 6,408 | — | Form 4 |
| Jun 3, 2026 | Klein Peter S Director | Award | 6,408 | — | Form 4 |
| Jun 3, 2026 | Krognes Steve E. Director | Award | 6,408 | — | Form 4 |
| Jun 3, 2026 | Schenkein David P Director | Award | 6,408 | — | Form 4 |
| Jun 3, 2026 | Thornberry Nancy Director | Award | 6,408 | — | Form 4 |
| Jun 3, 2026 | Van Hauwermeiren Timothy Director | Award | 6,408 | — | Form 4 |
| Jun 3, 2026 | Cook Jennifer E. Director | Award | 6,408 | — | Form 4 |
| Jun 3, 2026 | BAKER BROS. ADVISORS LP Director | Award | 6,408 | — | Form 4 |
| Jun 3, 2026 | BAKER BROS. ADVISORS LP Director | Award | 6,408 | — | Form 4 |
| Jan 6, 2026 | Watts Ryan J. President and CEO · Director | Sale | 35,198 | $581K | Form 4 |
| Jan 6, 2026 | Schuth Alexander O. COFO and Secretary | Sale | 17,218 | $284K | Form 4 |
| Jan 3, 2026 | Schuth Alexander O. COFO and Secretary | Award | 57,700 | — | Form 4 |
| Jan 3, 2026 | Watts Ryan J. President and CEO · Director | Award | 78,960 | — | Form 4 |
| Nov 4, 2025 | Van Hauwermeiren Timothy Director | Award | 10,632 | — | Form 4 |
| Sep 3, 2025 | Watts Ryan J. President and CEO · Director | Gift | 50,000 | — | Form 4 |
| Aug 12, 2025 | Schuth Alexander O. COFO and Secretary | Sale | 2,937 | $40K | Form 4 |
| Aug 12, 2025 | Ho Carole Chief Medical Officer | Sale | 2,937 | $40K | Form 4 |
| Aug 13, 2025 | Ho Carole Chief Medical Officer | Sale | 806 | $12K | Form 4 |
| Aug 5, 2025 | Ho Carole Chief Medical Officer | Option | 44,655 | $30K | Form 4 |
| Jul 9, 2025 | Watts Ryan J. President and CEO · Director | Option | 40,000 | $211K | Form 4 |
| Jul 9, 2025 | Watts Ryan J. President and CEO · Director | Option | 455,282 | $310K | Form 4 |
| Jul 9, 2025 | Watts Ryan J. President and CEO · Director | Sale | 495,282 | $7.43M⚡ | Form 4 |
| Jun 3, 2025 | BAKER BROS. ADVISORS LP Director | Award | 10,565 | — | Form 4 |
| Jun 3, 2025 | BAKER BROS. ADVISORS LP Director | Award | 10,565 | — | Form 4 |
| Jun 3, 2025 | Cook Jennifer E. Director | Award | 6,037 | — | Form 4 |
Watts Ryan J.
President and CEO · Director
Date
Jan 6
Shares
35,198
Price
$16.50
Value
$581K
Schuth Alexander O.
COFO and Secretary
Date
Jan 6
Shares
17,218
Price
$16.50
Value
$284K
Watts Ryan J.
President and CEO · Director
Date
Jan 3
Shares
78,960
Price
—
Value
—
Watts Ryan J.
President and CEO · Director
Date
Sep 3
Shares
50,000
Price
—
Value
—
Schuth Alexander O.
COFO and Secretary
Date
Aug 12
Shares
2,937
Price
$13.58
Value
$40K
Watts Ryan J.
President and CEO · Director
Date
Jul 9
Shares
40,000
Price
$5.28
Value
$211K
Watts Ryan J.
President and CEO · Director
Date
Jul 9
Shares
455,282
Price
$0.68
Value
$310K
Watts Ryan J.
President and CEO · Director
Date
Jul 9
Shares
495,282
Price
$15.00
Value
$7.43M ⚡
⚡ = value ≥ $1M · Award/Option price shows — · formType=4 · securityName=Common Stock · url → sec.gov/Archives/edgar
▸ Source: SEC EDGAR · Form 4 filings · ⚡ = value ≥ $1M · Award/Option price shows —
About DNLI insider trading
DNLI insider trades
Denali Therapeutics Inc. (DNLI) insider trading data is sourced from SEC Form 4 filings submitted by corporate insiders, including Watts Ryan J. (President and CEO · Director), Schuth Alexander O. (COFO and Secretary), Ho Carole (Chief Medical Officer). Over the past 12 months, 5 insiders have filed transactions with the SEC. DNLI insiders have been primarily selling, which may reflect pre-scheduled Rule 10b5-1 plan executions.
For Denali Therapeutics Inc.'s institutional ownership breakdown and insider ownership percentage, see the Ownership tab → Ownership tab →
Frequently asked questions
DNLI insider trading · 5 questionsThe insiders of Denali Therapeutics Inc. (DNLI) include executives and directors such as Watts Ryan J. (President and CEO · Director), Schuth Alexander O. (COFO and Secretary), Ho Carole (Chief Medical Officer), among others. Over the past 12 months, 5 insiders have filed Form 4 transactions with the SEC. Insider transactions are required to be reported within 2 business days of the trade date.
▸ Source: FMP /stable/insider-trading/search · SEC EDGAR Form 3 & 4 · acquisitionOrDisposition A=Buy, D=Sell · RSU vesting (M-Exempt) excluded from sentiment bar · As of Jun 8, 2026