Prime Medicine, Inc.
Prime Medicine, Inc. (PRME) Insider Trading
Form 4 buy vs sell counts, ratio, and sentiment — switch this quarter or last 12 months; chart and transactions below.
SEC EDGAR · FMP · PRME · as of Jun 8, 2026
Activity summary
Buy transactions
11
P-Purchase only
Sell transactions
0
12 Months
Buy/Sell ratio
∞
Buy/Sell (by trades)
Overall sentiment
Prime Medicine, Inc. insiders have been net buyers of shares over the past 12 Months, which may signal confidence in the company's outlook.
▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · Buy = P-Purchase only · Sell = S-Sale only
As of Jun 8, 2026
PRME insider buying and selling by quarter
PRME insider selling · PRME insider buying stocks · quarterly insider activity
Mobile shows last 4Q · Desktop shows full 8Q
▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · last 8 quarters
As of Jun 8, 2026
Active insiders
Most active in past 12 months · PRME ceo insider trading
Showing all insiders · Click a card to filter the transactions table below
▸ Aggregated from reportingName · top 5 by trade count (12M) · no extra API
Recent insider transactions
PRME executive sell shares · PRME board member insider trading · PRME insider trading SEC filing
Scroll horizontally to see all columns
| Date | Insider | Type | Shares | Value | Filing |
|---|---|---|---|---|---|
| Aug 1, 2025 | GV 2021 GP, L.L.C. 10 percent owner | Purchase | 1,500,000 | $4.95M⚡ | Form 4 |
| Aug 1, 2025 | NELSEN ROBERT Director | Purchase | 3,030,300 | $10.00M⚡ | Form 4 |
| Aug 1, 2025 | ARCH Venture Partners XII, LLC 10 percent owner | Purchase | 3,030,300 | $10.00M⚡ | Form 4 |
| Aug 1, 2025 | ARCH Venture Partners X, LLC 10 percent owner | Purchase | 3,030,300 | $10.00M⚡ | Form 4 |
| Jun 30, 2025 | Liu David R. 10 percent owner | Purchase | 21,000 | $53K | Form 4 |
| Jun 23, 2025 | Liu David R. 10 percent owner | Purchase | 21,000 | $45K | Form 4 |
| Jun 16, 2025 | Liu David R. 10 percent owner | Purchase | 21,000 | $31K | Form 4 |
| Jun 11, 2025 | Liu David R. 10 percent owner | Purchase | 21,000 | $34K | Form 4 |
| May 20, 2025 | Brudnick Richard Chief Business Officer | Purchase | 20,000 | $24K | Form 4 |
| May 21, 2025 | LEE ANN L. Chief Technical Officer | Purchase | 100,000 | $113K | Form 4 |
| May 21, 2025 | Reine Allan CEO · Director | Purchase | 125,000 | $147K | Form 4 |
| Oct 8, 2024 | Gottesdiener Keith Michael See Remarks · Director | Gift | 226,925 | — | Form 4 |
| Oct 8, 2024 | Gottesdiener Keith Michael See Remarks · Director | Gift | 226,925 | — | Form 4 |
GV 2021 GP, L.L.C.
10 percent owner
Date
Aug 1
Shares
1,500,000
Price
$3.30
Value
$4.95M ⚡
ARCH Venture Partners XII, LLC
10 percent owner
Date
Aug 1
Shares
3,030,300
Price
$3.30
Value
$10.00M ⚡
ARCH Venture Partners X, LLC
10 percent owner
Date
Aug 1
Shares
3,030,300
Price
$3.30
Value
$10.00M ⚡
Brudnick Richard
Chief Business Officer
Date
May 20
Shares
20,000
Price
$1.19
Value
$24K
LEE ANN L.
Chief Technical Officer
Date
May 21
Shares
100,000
Price
$1.13
Value
$113K
Gottesdiener Keith Michael
See Remarks · Director
Date
Oct 8
Shares
226,925
Price
—
Value
—
Gottesdiener Keith Michael
See Remarks · Director
Date
Oct 8
Shares
226,925
Price
—
Value
—
▸ Source: SEC EDGAR · Form 4 filings · ⚡ = value ≥ $1M · Award/Option price shows —
About PRME insider trading
PRME insider trades
Prime Medicine, Inc. (PRME) insider trading data is sourced from SEC Form 4 filings submitted by corporate insiders, including Liu David R. (10 percent owner), GV 2021 GP, L.L.C. (10 percent owner), NELSEN ROBERT (Director). Over the past 12 months, 5 insiders have filed transactions with the SEC. PRME insiders have been primarily buying, which may reflect pre-scheduled Rule 10b5-1 plan executions.
For Prime Medicine, Inc.'s institutional ownership breakdown and insider ownership percentage, see the Ownership tab → Ownership tab →
Frequently asked questions
PRME insider trading · 5 questionsThe insiders of Prime Medicine, Inc. (PRME) include executives and directors such as Liu David R. (10 percent owner), GV 2021 GP, L.L.C. (10 percent owner), NELSEN ROBERT (Director), among others. Over the past 12 months, 5 insiders have filed Form 4 transactions with the SEC. Insider transactions are required to be reported within 2 business days of the trade date.
▸ Source: FMP /stable/insider-trading/search · SEC EDGAR Form 3 & 4 · acquisitionOrDisposition A=Buy, D=Sell · RSU vesting (M-Exempt) excluded from sentiment bar · As of Jun 8, 2026