Companies: 10,795·Total market cap: $144.5T
Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated

VRTXNASDAQHealthcare● Active
$447.26
+$0.43(+0.10%)
Market Cap$113.5B
P/E Ratio—
52W High$507.92
52W Low$362.5
Overview

Vertex Pharmaceuticals Incorporated (VRTX) Cash on Hand — Cash & Short-Term Investments

Cash & cash equivalents plus short-term investments from the balance sheet, YoY change, and net cash vs debt context.

VRTX · cash on hand · updated Dec 31, 2025

Core cash position

Cash & Short-Term Investments (CCE + ST Investments)
$6.61B▲ +8.1% vs prior year
FY · as of Dec 31, 2025 · Reported in USD
Cash & Cash Equiv. (CCE)
$5.09B
cashAndCashEquivalents
Short-Term Investments
$1.52B
shortTermInvestments
YoY Change vs Prior Year
+8.1%
vs prior fiscal year
Latest Quarter
$7.25B
Q1 2026
Data Scope & Methodology

Cash on Hand = Cash & Cash Equivalents (CCE) + Short-Term Investments, as reported on the balance sheet (10-K/10-Q). Also referred to as cash reserves or cash position. Not free cash flow.

Source: FMP /balance-sheet-statement · SEC 10-K / 10-Q · Reported in USD

Source: FMP /balance-sheet-statement · SEC 10-K / 10-Q · USDUpdated: December 31, 2025

Net cash vs debt

Cash & ST Investments$6.61BCash on Hand
Total Debt$3.88BTotal Debt
Net Cash / Net Debt+$2.73BNet Cash Position
Cash vs Debt Ratio
Cash 63%Debt 37%

Vertex Pharmaceuticals Incorporated has a net cash position of $2.73B, holding more cash than debt.

Net Cash = Cash & ST Investments − Total Debt$6.61B − $3.88B = +$2.73B

Cash on hand history

YoY Increase
YoY Decrease
Latest Year
VRTX annual cash on hand history · Cash & Short-Term Investments · Source: FMP /balance-sheet-statement

Annual cash on hand by year

DateCash & ST InvestmentsYoY Change
Dec 31, 2025Latest$6.61B+8.1%
Dec 31, 2024$6.12B-45.5%
Dec 31, 2023$11.22B+4.1%
Dec 31, 2022$10.78B+43.2%
Dec 31, 2021$7.52B+13.0%
VRTX cash on hand annual historical data · Cash & Short-Term Investments per balance sheet (10-K/10-Q) · Reported in USD · Source: FMP /balance-sheet-statement

Healthcare Sector Cash Reserves Comparison

#CompanyCash & ST Inv.Cash/MCap
#1
UnitedHealth Group Incorporated
UnitedHealth Group Incorporated
UNH
$28.12B7.7%#2
Johnson & Johnson
Johnson & Johnson
JNJ
$20.10B3.6%#3
Eli Lilly and Company
Eli Lilly and Company
LLY
$7.27B0.7%
#4
Vertex Pharmaceuticals Incorporated
Vertex Pharmaceuticals IncorporatedYOU
VRTX
$6.61B5.8%
#5
AbbVie Inc.
AbbVie Inc.
ABBV
$5.26B1.3%
Healthcare sector cash reserves · Source: FMP /balance-sheet-statement + /profile · Sorted by Cash desccompanies with most cash on hand →

About cash on hand & methodology

Vertex Pharmaceuticals Incorporated (VRTX) cash on hand as of December 31, 2025 is $6.61B, comprising $5.09B in cash and cash equivalents (CCE) plus $1.52B in short-term investments — reported as Vertex Pharmaceuticals Incorporated cash and short-term investments on the balance sheet (10-K filing). Also referred to as Vertex Pharmaceuticals Incorporated cash reserves or cash position.

Vertex Pharmaceuticals Incorporated annual cash on hand history shows increased +8.1% in 2025: increased +8.1% in 2025. Vertex Pharmaceuticals Incorporated cash reserves in 2025 reflect the company's capital allocation strategy.

Vertex Pharmaceuticals Incorporated carries total debt of $3.88B against cash of $6.61B, resulting in a net cash position of +$2.73B. For the full balance sheet, see the Financials → Balance Sheet tab.

Figures tie to SEC 10-K/10-Q balance sheet disclosures and FMP /balance-sheet-statement where noted.
Financial statementsFree cash flowNet incomeRevenueMarket capP/E ratioEarningsPrice history

Frequently asked questions

VRTX cash on hand · 5 questions

As of December 31, 2025, Vertex Pharmaceuticals Incorporated (VRTX) has $6.61B in cash on hand — defined as cash and short-term investments on the balance sheet. This includes $5.09B in cash and cash equivalents (CCE) plus $1.52B in short-term investments. Latest quarter (March 31, 2026): $7.25B. Data sourced from the annual 10-K filing via FMP.

VRTX cash on handVRTX cash reservesVRTX cash 2025how much cash does VRTX have

▸ Source: FMP /balance-sheet-statement · US GAAP · Vertex Pharmaceuticals Incorporated · Vertex Pharmaceuticals Incorporated SEC 10-K & 10-Q filings · US GAAP · Last updated: December 31, 2025