Companies: 10,795·Total market cap: $144.5T
Alnylam Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc.

ALNYNASDAQHealthcare● Active
$289.83
$-13.22(-4.36%)
Market Cap$38.7B
P/E Ratio
52W High$495.55
52W Low$283.1

Alnylam Pharmaceuticals, Inc. (ALNY) Insider Trading

Form 4 buy vs sell counts, ratio, and sentiment — switch this quarter or last 12 months; chart and transactions below.

SEC EDGAR · FMP · ALNY · as of Jun 8, 2026

Activity summary

Buy transactions

0

P-Purchase only

Sell transactions

418

12 Months

Buy/Sell ratio

0.00

Buy/Sell (by trades)

Overall sentiment

BEARISH
↑ Buy 0%Active transactions only · RSU vesting excluded100% Sell ↓

Alnylam Pharmaceuticals, Inc. insiders have been primarily selling shares over the past 12 Months. Selling activity is often driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment toward the company.

Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · Buy = P-Purchase only · Sell = S-Sale only

As of Jun 8, 2026

ALNY insider buying and selling by quarter

ALNY insider selling · ALNY insider buying stocks · quarterly insider activity

Total insider buying (incl. awards)Total insider selling
300K150K0
2025 Q3
2025 Q4
2026 Q1
2026 Q2

Mobile shows last 4Q · Desktop shows full 8Q

Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · last 8 quarters

As of Jun 8, 2026

Active insiders

Most active in past 12 months · ALNY ceo insider trading

Showing all insiders · Click a card to filter the transactions table below

Aggregated from reportingName · top 5 by trade count (12M) · no extra API

Recent insider transactions

ALNY executive sell shares · ALNY board member insider trading · ALNY insider trading SEC filing

Showing 85 most recent · Common Stock · Form 4 only

Scroll horizontally to see all columns

PYOTT DAVID E I

Director

Option

Date

Jun 1

Shares

3,830

Price

Value

View Form 4 on SEC.gov

PYOTT DAVID E I

Director

Sale

Date

Jun 1

Shares

921

Price

$297.71

Value

$274K

View Form 4 on SEC.gov

PYOTT DAVID E I

Director

Sale

Date

Jun 1

Shares

1,175

Price

$298.91

Value

$351K

View Form 4 on SEC.gov

PYOTT DAVID E I

Director

Sale

Date

Jun 1

Shares

1,222

Price

$299.87

Value

$366K

View Form 4 on SEC.gov

PYOTT DAVID E I

Director

Sale

Date

Jun 1

Shares

495

Price

$300.72

Value

$149K

View Form 4 on SEC.gov

PYOTT DAVID E I

Director

Sale

Date

Jun 1

Shares

17

Price

$302.65

Value

$5K

View Form 4 on SEC.gov

Sigal Charles Elliott

Director

Award

Date

May 20

Shares

671

Price

Value

View Form 4 on SEC.gov

SCHULMAN AMY W

Director

Award

Date

May 20

Shares

838

Price

Value

View Form 4 on SEC.gov

Reitan Colleen F

Director

Award

Date

May 20

Shares

671

Price

Value

View Form 4 on SEC.gov

PYOTT DAVID E I

Director

Award

Date

May 20

Shares

671

Price

Value

View Form 4 on SEC.gov

KELLOGG PETER N

Director

Award

Date

May 20

Shares

671

Price

Value

View Form 4 on SEC.gov

HAMBURG MARGARET A

Director

Award

Date

May 20

Shares

671

Price

Value

View Form 4 on SEC.gov

BRANDICOURT OLIVIER

Director

Award

Date

May 20

Shares

671

Price

Value

View Form 4 on SEC.gov

Ausiello Dennis A

Director

Award

Date

May 20

Shares

671

Price

Value

View Form 4 on SEC.gov

Arbuckle Stuart A

Director

Award

Date

May 20

Shares

671

Price

Value

View Form 4 on SEC.gov

SCHULMAN AMY W

Director

Option

Date

May 13

Shares

11,250

Price

$70.20

Value

$790K

View Form 4 on SEC.gov

McLaughlin Melissa

Chief Human Resources Officer

Sale

Date

Apr 2

Shares

265

Price

$316.61

Value

$84K

View Form 4 on SEC.gov

McLaughlin Melissa

Chief Human Resources Officer

Sale

Date

Apr 2

Shares

359

Price

$317.44

Value

$114K

View Form 4 on SEC.gov

McLaughlin Melissa

Chief Human Resources Officer

Sale

Date

Apr 2

Shares

209

Price

$318.47

Value

$67K

View Form 4 on SEC.gov

McLaughlin Melissa

Chief Human Resources Officer

Sale

Date

Apr 2

Shares

86

Price

$319.69

Value

$27K

View Form 4 on SEC.gov

McLaughlin Melissa

Chief Human Resources Officer

Sale

Date

Apr 2

Shares

147

Price

$320.62

Value

$47K

View Form 4 on SEC.gov

McLaughlin Melissa

Chief Human Resources Officer

Sale

Date

Apr 2

Shares

224

Price

$321.64

Value

$72K

View Form 4 on SEC.gov

McLaughlin Melissa

Chief Human Resources Officer

Sale

Date

Apr 2

Shares

245

Price

$322.86

Value

$79K

View Form 4 on SEC.gov

McLaughlin Melissa

Chief Human Resources Officer

Sale

Date

Apr 2

Shares

81

Price

$323.64

Value

$26K

View Form 4 on SEC.gov

McLaughlin Melissa

Chief Human Resources Officer

Sale

Date

Apr 2

Shares

8

Price

$325.49

Value

$3K

View Form 4 on SEC.gov

⚡ = value ≥ $1M · Award/Option price shows — · formType=4 · securityName=Common Stock · url → sec.gov/Archives/edgar

1 / 4

Source: SEC EDGAR · Form 4 filings · ⚡ = value ≥ $1M · Award/Option price shows —

About ALNY insider trading

ALNY insider trades

Alnylam Pharmaceuticals, Inc. (ALNY) insider trading data is sourced from SEC Form 4 filings submitted by corporate insiders, including Poulton Jeffrey V. (EVP, Chief Financial Officer), McLaughlin Melissa (Chief Human Resources Officer), Garg Pushkal (EVP Chief R&D). Over the past 12 months, 5 insiders have filed transactions with the SEC. ALNY insiders have been primarily selling, which may reflect pre-scheduled Rule 10b5-1 plan executions.

For Alnylam Pharmaceuticals, Inc.'s institutional ownership breakdown and insider ownership percentage, see the Ownership tab → Ownership tab →

Buy/Sell signal logic
acquisitionOrDisposition field:
A = Acquisition (buy) · D = Disposition (sell)
RSU vesting (M-Exempt) excluded from sentiment
Form 4SEC filing required within 2 business days of any insider transaction
10b5-1Pre-scheduled trading plan that allows insiders to sell on autopilot
Open MktDirect purchase or sale on the open market (excludes awards, options)

Frequently asked questions

ALNY insider trading · 5 questions

The insiders of Alnylam Pharmaceuticals, Inc. (ALNY) include executives and directors such as Poulton Jeffrey V. (EVP, Chief Financial Officer), McLaughlin Melissa (Chief Human Resources Officer), Garg Pushkal (EVP Chief R&D), among others. Over the past 12 months, 5 insiders have filed Form 4 transactions with the SEC. Insider transactions are required to be reported within 2 business days of the trade date.

ALNY board member insider tradingwho are ALNY insidersALNY insider rosterAlnylam Pharmaceuticals, Inc. executives insider activity

Source: FMP /stable/insider-trading/search · SEC EDGAR Form 3 & 4 · acquisitionOrDisposition A=Buy, D=Sell · RSU vesting (M-Exempt) excluded from sentiment bar · As of Jun 8, 2026