Aytu BioPharma, Inc.
Aytu BioPharma, Inc. (AYTU) Stock Ownership
Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.
SEC 13F · FMP · AYTU · as of Sep 30, 2025
Ownership Breakdown
31
Institutional Holders
$6.73M
Total Inst. Value
▼ $715,501 vs Q2
8.10M
Shares Outstanding
freeFloat 93.94%
3.58M
13F Shares Held
▲ 164,071 vs Q2
Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.
Top Institutional Holders
AYTU largest shareholders · institutional ownership
Q3 2025 · SEC 13F
Showing top 10 holders
| Holder | Shares | % Owned | Weight | Value | Reported | Change |
|---|---|---|---|---|---|---|
NANTAHALA CAPITAL MANAGEMENT, LLC pharmaceutical preparations | 1.09M | 17.31% | 17.31% | $2.04B | Nov 14, 2025 | — held |
STONEPINE CAPITAL MANAGEMENT, LLC pharmaceutical preparations | 891.9K | 14.20% | 14.20% | $1.68B | Nov 13, 2025 | ▲ 79.2K |
AWM INVESTMENT COMPANY, INC. pharmaceutical preparations | 619.6K | 9.87% | 9.87% | $1.16B | Nov 13, 2025 | ▼ 300 |
VANGUARD GROUP INC pharmaceutical preparations | 278.6K | 4.44% | 4.44% | $523.74M | Nov 7, 2025 | ▲ 250.7K |
DIADEMA PARTNERS LP pharmaceutical preparations | 272.7K | 4.34% | 4.34% | $512.62M | Nov 14, 2025 | NEW |
RENAISSANCE TECHNOLOGIES LLC pharmaceutical preparations | 95.1K | 1.51% | 1.51% | $178.83M | Nov 13, 2025 | ▲ 5.2K |
GEODE CAPITAL MANAGEMENT, LLC pharmaceutical preparations | 71.0K | 1.13% | 1.13% | $133.52M | Nov 12, 2025 | ▲ 17.1K |
TWO SIGMA INVESTMENTS, LP pharmaceutical preparations | 68.7K | 1.09% | 1.09% | $129.22M | Nov 14, 2025 | ▲ 33.7K |
PERSISTENT ASSET PARTNERS LTD pharmaceutical preparations | 62.5K | 99.45% | 99.45% | $117.41M | Jan 15, 2026 | NEW |
TWO SIGMA ADVISERS, LP pharmaceutical preparations | 39.8K | 63.38% | 63.38% | $74.82M | Nov 14, 2025 | NEW |
Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).
Institutional Activity
Q3 2025 vs prior quarter
Q3 2025
9
Increased
+388.0K shares6
New Positions
first time holders2
Decreased
−449 shares5
Sold Out
fully exitedNet shares change (top 50)
+387.5K
+388.0K / −449
Net new holders
+8
6 new / 5 exited
Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).
Insider Buying vs Selling
AYTU insider trading · insider activity
Source: SEC Form 4
Insiders have been net buyers of shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.
3
Buy transactions
0
Sell transactions
0.00
Buy/Sell ratio
$0M
Total disposed
Recent Insider Transactions
Showing 10 most recent · Common Stock only
| Name · Role | Date | Type | Shares | Price | Value | After Trans. | Filing |
|---|---|---|---|---|---|---|---|
PYSZCZYMUKA GREG Chief Commercial Officer | Oct 3, 2025 | Award | 12,500 | — | — | 36.1K | Form 4 ↗ |
Disbrow Jarrett Chief Business Officer | Oct 3, 2025 | Award | 12,500 | — | — | 61.6K | Form 4 ↗ |
Disbrow Jarrett Chief Business Officer | Oct 3, 2025 | Award | 19,606 | — | — | 49.1K | Form 4 ↗ |
Selhorn Ryan J Chief Financial Officer | Oct 3, 2025 | Award | 17,500 | — | — | 49.7K | Form 4 ↗ |
Selhorn Ryan J Chief Financial Officer | Oct 3, 2025 | Award | 16,243 | — | — | 32.2K | Form 4 ↗ |
Disbrow Joshua R. Chief Executive Officer | Oct 3, 2025 | Award | 22,500 | — | — | 207.2K | Form 4 ↗ |
Disbrow Joshua R. Chief Executive Officer | Oct 3, 2025 | Award | 31,446 | — | — | 184.7K | Form 4 ↗ |
LIU VIVIAN H director | Oct 3, 2025 | Award | 10,000 | — | — | 19.8K | Form 4 ↗ |
JAIN ABHINAV director | Oct 3, 2025 | Award | 10,000 | — | — | 19.5K | Form 4 ↗ |
DOCKERY CARL director | Oct 3, 2025 | Award | 10,000 | — | — | 20.4K | Form 4 ↗ |
Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.
About institutional & insider ownership
Aytu BioPharma, Inc. (AYTU) is primarily owned by institutional investors, who hold approximately 44.2% of total shares outstanding. Company insiders own approximately 6.06%, while retail and public investors account for the remaining 49.74%.
The largest institutional shareholder of Aytu BioPharma, Inc. is NANTAHALA CAPITAL MANAGEMENT, LLC, holding approximately 1.09 million shares — equal to 17.31% of outstanding shares — as of September 30, 2025.
A total of 31 institutional investors currently hold AYTU stock, with a combined institutional value of approximately $6,730,606 as of the most recent 13F filing period.
Frequently asked questions
AYTU ownershipAytu BioPharma, Inc. (AYTU) is primarily owned by institutional investors, who hold approximately 44.2% of shares. The largest shareholder is NANTAHALA CAPITAL MANAGEMENT, LLC with a 17.31% stake. Company insiders hold 6.06%. Data sourced from SEC Form 13F as of September 30, 2025.