Companies: 10,795·Total market cap: $144.5T
Bicycle Therapeutics plc

Bicycle Therapeutics plc

BCYCNASDAQHealthcare● Active
$4.11
$-0.09(-2.14%)
Market Cap$285211539
P/E Ratio
52W High$9.36
52W Low$4.09

Bicycle Therapeutics plc (BCYC) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · BCYC · as of Sep 30, 2025

Ownership Breakdown

Institutions 53.18%
Insiders 11.41%
Public 35.4%

103

Institutional Holders

▼ 14 vs Q2

$285.62M

Total Inst. Value

▼ $718,857 vs Q2

69.39M

Shares Outstanding

freeFloat 88.59%

36.91M

13F Shares Held

▼ 4.29M vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

BCYC largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

BAKER BROS. ADVISORS LP

pharmaceutical preparations

10.89M15.72%

15.72%

$84.25BNov 14, 2025— held

FCPM III SERVICES B.V.

pharmaceutical preparations

3.45M4.99%

4.99%

$26.72BNov 14, 2025— held

ARMISTICE CAPITAL, LLC

pharmaceutical preparations

2.98M4.30%

4.30%

$23.05BNov 17, 2025 178.0K

WESTFIELD CAPITAL MANAGEMENT CO LP

pharmaceutical preparations

2.95M4.26%

4.26%

$22.85BNov 12, 2025 172.1K

SIREN, L.L.C.

pharmaceutical preparations

2.01M2.91%

2.91%

$15.58BNov 13, 2025— held

LONG FOCUS CAPITAL MANAGEMENT, LLC

pharmaceutical preparations

1.42M2.05%

2.05%

$10.98BNov 14, 2025 101.4K

PRICE T ROWE ASSOCIATES INC /MD/

pharmaceutical preparations

1.38M2.00%

2.00%

$10.72BNov 14, 2025 83.6K

ACADIAN ASSET MANAGEMENT LLC

pharmaceutical preparations

1.31M1.90%

1.90%

$10.15BNov 13, 2025 616.1K

CANDRIAM S.C.A.

pharmaceutical preparations

1.17M1.69%

1.69%

$9.07BNov 6, 2025— held

PRINCIPAL FINANCIAL GROUP INC

pharmaceutical preparations

1.15M1.66%

1.66%

$8.89BNov 4, 2025 451.1K

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBullish — more buying than selling

24

Increased

+2.57M shares

1

New Positions

first time holders

15

Decreased

−2.65M shares

0

Sold Out

fully exited

Net shares change (top 50)

89.7K

+2.57M / −2.65M

Net new holders

+10

1 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

BCYC insider trading · insider activity

Source: SEC Form 4

Buy 0%Active transactions only100% Sell

Insiders have been primarily selling shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

0

Buy transactions

11

Sell transactions

0.00

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Hannay Michael Charles Ferguson

CHIEF PROD & SUPPLY CHAIN OFF

Apr 2, 2026Sale1,521$4.91$7.5K96.4KForm 4 ↗

Hannay Michael Charles Ferguson

CHIEF PROD & SUPPLY CHAIN OFF

Apr 6, 2026Sale251$5.05$1.3K96.1KForm 4 ↗

Thompson Travis Alvin

Chief Financial Officer

Apr 2, 2026Sale799$4.91$3.9K65.5KForm 4 ↗

Thompson Travis Alvin

Chief Financial Officer

Apr 6, 2026Sale102$5.05$515.165.4KForm 4 ↗

Perry Jennifer Scott

Chief Operating Officer

Apr 2, 2026Sale1,038$4.91$5.1K92.8KForm 4 ↗

Perry Jennifer Scott

Chief Operating Officer

Apr 6, 2026Sale37$5.05$186.8592.8KForm 4 ↗

Perry Jennifer Scott

Chief Operating Officer

Apr 6, 2026Sale333$5.04$1.7K92.5KForm 4 ↗

Lee Kevin

CHIEF EXECUTIVE OFFICER

Apr 2, 2026Sale5,967$4.91$29.3K613.0KForm 4 ↗

Lee Kevin

CHIEF EXECUTIVE OFFICER

Apr 6, 2026Sale1,716$5.05$8.7K611.3KForm 4 ↗

Skynner Michael

CHIEF SCIENTIFIC OFFICER

Apr 2, 2026Sale1,879$4.91$9.2K160.1KForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Bicycle Therapeutics plc (BCYC) is primarily owned by institutional investors, who hold approximately 53.2% of total shares outstanding. Company insiders own approximately 11.41%, while retail and public investors account for the remaining 35.40%.

The largest institutional shareholder of Bicycle Therapeutics plc is BAKER BROS. ADVISORS LP, holding approximately 10.89 million shares — equal to 15.72% of outstanding shares — as of September 30, 2025.

A total of 103 institutional investors currently hold BCYC stock, with a combined institutional value of approximately $285,619,779 as of the most recent 13F filing period.

Frequently asked questions

BCYC ownership

Bicycle Therapeutics plc (BCYC) is primarily owned by institutional investors, who hold approximately 53.2% of shares. The largest shareholder is BAKER BROS. ADVISORS LP with a 15.72% stake. Company insiders hold 11.41%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns BCYC stockBCYC ownership structureSEC Form 13F institutional holdingsBCYC float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025