Companies: 10,795·Total market cap: $144.5T
Blueprint Medicines Corporation

Blueprint Medicines Corporation

BPMCNASDAQHealthcare
$129.46
+$0.18(+0.14%)
Market Cap$8.4B
P/E Ratio
52W High$129.55
52W Low$73.04

Blueprint Medicines Corporation (BPMC) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · BPMC · as of Jun 30, 2025

Ownership Breakdown

Institutions 99.6%
Insiders 7.09%
Public 0%

381

Institutional Holders

▲ 10 vs Q1

$8.24B

Total Inst. Value

▲ $2.13B vs Q1

64.58M

Shares Outstanding

freeFloat 92.91%

64.32M

13F Shares Held

▼ 4.80M vs Q1

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

BPMC largest shareholders · institutional ownership

Q2 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

VANGUARD GROUP INC

pharmaceutical preparations

6.42M10.09%

10.09%

$822.48BAug 11, 2025 223.9K

BLACKROCK, INC.

pharmaceutical preparations

6.12M9.62%

9.62%

$784.26BAug 12, 2025 592.3K

PENTWATER CAPITAL MANAGEMENT LP

pharmaceutical preparations

3.90M6.13%

6.13%

$499.90BAug 14, 2025NEW

STATE STREET CORP

pharmaceutical preparations

2.23M3.51%

3.51%

$285.97BAug 14, 2025 453.1K

UBS GROUP AG

pharmaceutical preparations

2.17M3.41%

3.41%

$277.77BAug 14, 2025 1.95M

FIL LTD

pharmaceutical preparations

1.76M2.77%

2.77%

$225.53BAug 14, 2025NEW

UBS OCONNOR LLC

pharmaceutical preparations

1.71M2.69%

2.69%

$219.65BAug 14, 2025 1.70M

BARCLAYS PLC

pharmaceutical preparations

1.56M2.45%

2.45%

$199.57BFeb 27, 2026 1.43M

GEODE CAPITAL MANAGEMENT, LLC

pharmaceutical preparations

1.54M2.42%

2.42%

$197.55BAug 8, 2025 18.4K

PRICE T ROWE ASSOCIATES INC /MD/

pharmaceutical preparations

1.46M2.30%

2.30%

$187.78BAug 14, 2025 3.95M

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q2 2025 vs prior quarter

Q2 2025

Net institutional sentimentBullish — more buying than selling

14

Increased

+9.73M shares

13

New Positions

first time holders

23

Decreased

−16.93M shares

0

Sold Out

fully exited

Net shares change (top 50)

7.20M

+9.73M / −16.93M

Net new holders

+4

13 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

BPMC insider trading · insider activity

Source: SEC Form 4

2

Buy transactions

20

Sell transactions

0.10

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Landsittel Michael

Chief Financial Officer

Jul 17, 2025Award21,35394.3KForm 4 ↗

Landsittel Michael

Chief Financial Officer

Jul 17, 2025D-Return51,10243.2KForm 4 ↗

Landsittel Michael

Chief Financial Officer

Jul 17, 2025D-Return25,000$61.31$1.53M0Form 4 ↗

Landsittel Michael

Chief Financial Officer

Jul 17, 2025D-Return25,000$43.15$1.08M0Form 4 ↗

Landsittel Michael

Chief Financial Officer

Jul 17, 2025D-Return10,000$15.01$150.1K0Form 4 ↗

Landsittel Michael

Chief Financial Officer

Jul 17, 2025U-Tender43,1750Form 4 ↗

Landsittel Michael

Chief Financial Officer

Jul 17, 2025D-Return19,500$86.60$1.69M0Form 4 ↗

Landsittel Michael

Chief Financial Officer

Jul 17, 2025D-Return25,000$54.13$1.35M0Form 4 ↗

Landsittel Michael

Chief Financial Officer

Jul 17, 2025D-Return25,000$95.12$2.38M0Form 4 ↗

Landsittel Michael

Chief Financial Officer

Jul 17, 2025D-Return22,000$96.57$2.12M0Form 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Blueprint Medicines Corporation (BPMC) is primarily owned by institutional investors, who hold approximately 99.6% of total shares outstanding. Company insiders own approximately 7.09%, while retail and public investors account for the remaining 0.00%.

The largest institutional shareholder of Blueprint Medicines Corporation is VANGUARD GROUP INC, holding approximately 6.42 million shares — equal to 10.09% of outstanding shares — as of June 30, 2025.

A total of 381 institutional investors currently hold BPMC stock, with a combined institutional value of approximately $8.24 billion as of the most recent 13F filing period.

Frequently asked questions

BPMC ownership

Blueprint Medicines Corporation (BPMC) is primarily owned by institutional investors, who hold approximately 99.6% of shares. The largest shareholder is VANGUARD GROUP INC with a 10.09% stake. Company insiders hold 7.09%. Data sourced from SEC Form 13F as of June 30, 2025.

who owns BPMC stockBPMC ownership structureSEC Form 13F institutional holdingsBPMC float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of June 30, 2025