Denali Therapeutics Inc.

DNLINASDAQHealthcare● Active

$19.29

$-0.23(-1.16%)

Market Cap$3.1B

P/E Ratio—

52W High$23.77

52W Low$12.58

Avg Volume1.8M

Open$19.85

Beta1.01

Employees Ownership Insider Trades

Denali Therapeutics Inc. (DNLI) Number of Employees – History & Annual Headcount

Annual SEC headcount, year-over-year change, and per-employee efficiency — chart and full history below.

SEC EDGAR · FMP · DNLI · as of Feb 26, 2026

Latest filing snapshot

503

+81+19.19%vs prior year

Denali Therapeutics Inc. (DNLI) employee data is sourced from the annual SEC 10-K filing. As of 2025, full-time employees only. Global consolidated headcount. View SEC filing ↗

SEC 10-K·Period end: 2025-12-31·Full-time · Global

Total Employees

503

Change (1Y)

+81

Growth % (1Y)

+19.19%

Revenue / Employee

—

Net Income / Employee

$-1.02M

Market Cap

$3.1B

DNLI Employee Count

2017 – 2025 · Annual · SEC filing

Source: SEC annual filings · Hover bar to view year data · Click to view original filing

Employees History

Filing Date	Period End	Employees	Change (1Y)	Growth (1Y)
2026-02-26	2025-12-31	503	+81	+19.19%
2025-02-27	2024-12-31	422	-23	-5.17%
2024-02-28	2023-12-31	445	+18	+4.22%
2023-02-27	2022-12-31	427	+47	+12.37%
2022-02-28	2021-12-31	380	+89	+30.58%
2021-02-26	2020-12-31	291	+30	+11.49%
2020-02-27	2019-12-31	261	+82	+45.81%
2019-03-12	2018-12-31	179	+49	+37.69%
2018-03-19	2017-12-31	130	—	—

▸ Source: SEC Annual Reports (Form 10-K / 20-F). Employee counts as of fiscal year end. Click the ↗ icon at the end of a row to open the original SEC filing in a new tab.

Related Companies — Employee Count

Biotechnology

#SymbolCompanyEmployeesMkt Cap

Denali Therapeutics Inc.YOU

503$3.1B #4

AGIO

Agios Pharmaceuticals, Inc.

486$1.6B #5

BEAM

Beam Therapeutics Inc.

393$3.0B #6

COGT

Cogent Biosciences, Inc.

Source: /stock-peers + /profile.fullTimeEmployees · Click row → /employees · Sorted by headcount · DNLI peer comparison

About DNLI employees

DNLI Employees · Headcount

Denali Therapeutics Inc. (DNLI) employee data is sourced from the annual SEC 10-K filing. As of 2025, Denali Therapeutics Inc. had 503 full-time employees globally. Full-time employees only. Global consolidated headcount.

Denali Therapeutics Inc.'s workforce increased by 81 (19.19%) in 2025 compared to the prior fiscal year. The historical trend reflects the company's expansion and contraction cycles.

Revenue Financial statements Net income SEC filings Price history Forecast & ratings Ownership Earnings

Frequently Asked Questions

DNLI Employees · 5 questions

As of the latest SEC 10-K filing (2025), Denali Therapeutics Inc. had 503 full-time employees globally. This figure is sourced from the company's mandatory annual disclosure to the SEC.

Denali Therapeutics Inc. employee counthow many employees does Denali Therapeutics Inc. haveDNLI total employees 2025

▸ Data source: FMP /historical-employee-count · SEC EDGAR annual filings · As reported · Global consolidated headcount · As of 2026-02-26