
89bio, Inc.
89bio, Inc. (ETNB) Stock Ownership
Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.
SEC 13F · FMP · ETNB · as of Mar 31, 2025
Ownership Breakdown
199
Institutional Holders
▲ 37 vs Q4
$1.14B
Total Inst. Value
▲ $190.34M vs Q4
148.30M
Shares Outstanding
freeFloat 98.45%
154.33M
13F Shares Held
▲ 33.07M vs Q4
Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.
Top Institutional Holders
ETNB largest shareholders · institutional ownership
Q1 2025 · SEC 13F
Showing top 10 holders
| Holder | Shares | % Owned | Weight | Value | Reported | Change |
|---|---|---|---|---|---|---|
JANUS HENDERSON GROUP PLC pharmaceutical preparations | 20.46M | 13.98% | 13.98% | $165.29B | May 15, 2025 | ▲ 3.95M |
RA CAPITAL MANAGEMENT, L.P. pharmaceutical preparations | 19.89M | 13.59% | 13.59% | $144.60B | May 15, 2025 | ▲ 5.71M |
SUVRETTA CAPITAL MANAGEMENT, LLC pharmaceutical preparations | 14.34M | 9.79% | 9.79% | $104.22B | May 15, 2025 | ▲ 4.13M |
BLACKROCK, INC. pharmaceutical preparations | 10.08M | 6.88% | 6.88% | $73.25B | May 2, 2025 | ▲ 2.19M |
DEEP TRACK CAPITAL, LP pharmaceutical preparations | 9.32M | 6.37% | 6.37% | $67.73B | May 15, 2025 | ▲ 2.84M |
VANGUARD GROUP INC pharmaceutical preparations | 7.16M | 4.89% | 4.89% | $52.08B | May 9, 2025 | ▲ 1.47M |
AVORO CAPITAL ADVISORS LLC pharmaceutical preparations | 6.35M | 4.34% | 4.34% | $46.16B | May 15, 2025 | ▲ 2.25M |
CITADEL ADVISORS LLC pharmaceutical preparations | 5.09M | 3.48% | 3.48% | $36.98B | May 15, 2025 | ▲ 357.0K |
PICTET ASSET MANAGEMENT HOLDING SA pharmaceutical preparations | 4.20M | 2.87% | 2.87% | $30.57B | May 5, 2025 | ▲ 1.20M |
STATE STREET CORP pharmaceutical preparations | 4.03M | 2.75% | 2.75% | $29.30B | May 15, 2025 | ▲ 1.09M |
Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).
Institutional Activity
Q1 2025 vs prior quarter
Q1 2025
33
Increased
+32.12M shares11
New Positions
first time holders6
Decreased
−6.42M shares0
Sold Out
fully exitedNet shares change (top 50)
+25.70M
+32.12M / −6.42M
Net new holders
+38
11 new / 0 exited
Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).
Insider Buying vs Selling
ETNB insider trading · insider activity
Source: SEC Form 4
6
Buy transactions
83
Sell transactions
0.07
Buy/Sell ratio
$9M
Total disposed
Recent Insider Transactions
Showing 10 most recent · Common Stock only
| Name · Role | Date | Type | Shares | Price | Value | After Trans. | Filing |
|---|---|---|---|---|---|---|---|
RA CAPITAL MANAGEMENT, L.P.
| Oct 30, 2025 | D-Return | 45,150 | $9.98 | $450.6K | 0 | Form 4 ↗ |
RA CAPITAL MANAGEMENT, L.P.
| Oct 30, 2025 | D-Return | 12,500 | $24.16 | $302.0K | 0 | Form 4 ↗ |
RA CAPITAL MANAGEMENT, L.P.
| Oct 30, 2025 | D-Return | 56,400 | $9.60 | $541.4K | 0 | Form 4 ↗ |
RA CAPITAL MANAGEMENT, L.P.
| Oct 30, 2025 | D-Return | 7,000 | $21.40 | $149.8K | 0 | Form 4 ↗ |
RA CAPITAL MANAGEMENT, L.P.
| Oct 30, 2025 | D-Return | 7,000 | $24.29 | $170.0K | 0 | Form 4 ↗ |
RA CAPITAL MANAGEMENT, L.P.
| Oct 30, 2025 | D-Return | 27,400 | $14.70 | $402.8K | 0 | Form 4 ↗ |
RA CAPITAL MANAGEMENT, L.P.
| Oct 30, 2025 | D-Return | 335,364 | $14.50 | $4.86M | 0 | Form 4 ↗ |
RA CAPITAL MANAGEMENT, L.P.
| Oct 30, 2025 | D-Return | 4,331,081 | $0.00 | $4.3K | 0 | Form 4 ↗ |
RA CAPITAL MANAGEMENT, L.P.
| Oct 30, 2025 | D-Return | 25,000 | $2.64 | $66.0K | 0 | Form 4 ↗ |
LAPORTE KATHLEEN director | Oct 30, 2025 | D-Return | 45,150 | $9.98 | $450.6K | 0 | Form 4 ↗ |
Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.
About institutional & insider ownership
89bio, Inc. (ETNB) is primarily owned by institutional investors, who hold approximately 100.0% of total shares outstanding. Company insiders own approximately 1.55%, while retail and public investors account for the remaining 0.00%.
The largest institutional shareholder of 89bio, Inc. is JANUS HENDERSON GROUP PLC, holding approximately 20.46 million shares — equal to 13.98% of outstanding shares — as of March 31, 2025.
A total of 199 institutional investors currently hold ETNB stock, with a combined institutional value of approximately $1.14 billion as of the most recent 13F filing period.
Frequently asked questions
ETNB ownership89bio, Inc. (ETNB) is primarily owned by institutional investors, who hold approximately 100.0% of shares. The largest shareholder is JANUS HENDERSON GROUP PLC with a 13.98% stake. Company insiders hold 1.55%. Data sourced from SEC Form 13F as of March 31, 2025.