Edgewise Therapeutics, Inc.
Edgewise Therapeutics, Inc. (EWTX) Stock Ownership
Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.
SEC 13F · FMP · EWTX · as of Sep 30, 2025
Ownership Breakdown
179
Institutional Holders
▼ 4 vs Q2
$1.82B
Total Inst. Value
▲ $259.12M vs Q2
107.59M
Shares Outstanding
freeFloat 72.93%
111.96M
13F Shares Held
▼ 6.77M vs Q2
Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.
Top Institutional Holders
EWTX largest shareholders · institutional ownership
Q3 2025 · SEC 13F
Showing top 10 holders
| Holder | Shares | % Owned | Weight | Value | Reported | Change |
|---|---|---|---|---|---|---|
ORBIMED ADVISORS LLC pharmaceutical preparations | 15.52M | 14.79% | 14.79% | $251.71B | Nov 14, 2025 | — held |
RA CAPITAL MANAGEMENT, L.P. pharmaceutical preparations | 10.43M | 9.94% | 9.94% | $169.15B | Nov 14, 2025 | ▲ 525.8K |
BAKER BROS. ADVISORS LP pharmaceutical preparations | 7.31M | 6.96% | 6.96% | $118.50B | Nov 14, 2025 | — held |
BLACKROCK, INC. pharmaceutical preparations | 6.35M | 6.05% | 6.05% | $103.02B | Nov 12, 2025 | ▼ 429.6K |
PARADIGM BIOCAPITAL ADVISORS LP pharmaceutical preparations | 6.17M | 5.88% | 5.88% | $100.08B | Nov 14, 2025 | ▲ 27.8K |
NOVO HOLDINGS A/S pharmaceutical preparations | 5.35M | 5.10% | 5.10% | $86.78B | Nov 14, 2025 | — held |
BRAIDWELL LP pharmaceutical preparations | 5.21M | 4.97% | 4.97% | $84.52B | Nov 14, 2025 | — held |
JANUS HENDERSON GROUP PLC pharmaceutical preparations | 4.98M | 4.74% | 4.74% | $80.80B | Nov 14, 2025 | ▼ 524.0K |
VANGUARD GROUP INC pharmaceutical preparations | 4.80M | 4.58% | 4.58% | $77.92B | Nov 7, 2025 | ▼ 37.6K |
CORMORANT ASSET MANAGEMENT, LP pharmaceutical preparations | 4.01M | 3.82% | 3.82% | $65.04B | Nov 14, 2025 | ▼ 242.0K |
Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).
Institutional Activity
Q3 2025 vs prior quarter
Q3 2025
17
Increased
+3.13M shares0
New Positions
first time holders23
Decreased
−6.74M shares0
Sold Out
fully exitedNet shares change (top 50)
3.60M
+3.13M / −6.74M
Net new holders
-6
0 new / 0 exited
Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).
Insider Buying vs Selling
EWTX insider trading · insider activity
Source: SEC Form 4
Insiders have been primarily selling shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.
3
Buy transactions
5
Sell transactions
0.60
Buy/Sell ratio
$0M
Total disposed
Recent Insider Transactions
Showing 10 most recent · Common Stock only
| Name · Role | Date | Type | Shares | Price | Value | After Trans. | Filing |
|---|---|---|---|---|---|---|---|
Donovan Joanne M. CMO | May 5, 2026 | Sale | 50,000 | $38.57 | $1.93M | 4.4K | Form 4 ↗ |
Donovan Joanne M. CMO | May 4, 2026 | Sale | 5,230 | $31.29 | $163.7K | 4.4K | Form 4 ↗ |
Fox Jonathan C director | Apr 1, 2026 | Award | 339 | — | — | 24.5K | Form 4 ↗ |
Donovan Joanne M. CMO | Apr 1, 2026 | Sale | 28,662 | $32.31 | $926.1K | 9.6K | Form 4 ↗ |
Donovan Joanne M. CMO | Mar 31, 2026 | Sale | 21,338 | $32.12 | $685.3K | 9.6K | Form 4 ↗ |
Donovan Joanne M. CMO | Mar 27, 2026 | Sale | 9,623 | $30.98 | $298.1K | 16.3K | Form 4 ↗ |
Donovan Joanne M. CMO | Mar 27, 2026 | Sale | 6,735 | $30.98 | $208.6K | 9.6K | Form 4 ↗ |
Edris Badreddin director | Jan 21, 2026 | Sale | 13,690 | $29.44 | $403.0K | 121.6K | Form 4 ↗ |
Edris Badreddin director | Jan 21, 2026 | Sale | 17,236 | $29.44 | $507.4K | 104.4K | Form 4 ↗ |
Edris Badreddin director | Jan 21, 2026 | Sale | 7,605 | $29.44 | $223.9K | 96.8K | Form 4 ↗ |
Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.
About institutional & insider ownership
Edgewise Therapeutics, Inc. (EWTX) is primarily owned by institutional investors, who hold approximately 100.0% of total shares outstanding. Company insiders own approximately 27.07%, while retail and public investors account for the remaining 0.00%.
The largest institutional shareholder of Edgewise Therapeutics, Inc. is ORBIMED ADVISORS LLC, holding approximately 15.52 million shares — equal to 14.79% of outstanding shares — as of September 30, 2025.
A total of 179 institutional investors currently hold EWTX stock, with a combined institutional value of approximately $1.82 billion as of the most recent 13F filing period.
Frequently asked questions
EWTX ownershipEdgewise Therapeutics, Inc. (EWTX) is primarily owned by institutional investors, who hold approximately 100.0% of shares. The largest shareholder is ORBIMED ADVISORS LLC with a 14.79% stake. Company insiders hold 27.07%. Data sourced from SEC Form 13F as of September 30, 2025.