Companies: 10,795·Total market cap: $144.5T
Insmed Incorporated

Insmed Incorporated

INSMNASDAQHealthcare● Active
$92.71
$-1.51(-1.60%)
Market Cap$20.1B
P/E Ratio
52W High$212.75
52W Low$70.57

Insmed Incorporated (INSM) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · INSM · as of Sep 30, 2025

Ownership Breakdown

Institutions 97.29%
Insiders 8.52%
Public 0%

624

Institutional Holders

▲ 61 vs Q2

$30.33B

Total Inst. Value

▲ $9.18B vs Q2

216.75M

Shares Outstanding

freeFloat 91.48%

210.88M

13F Shares Held

▲ 490,062 vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

INSM largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

JPMORGAN CHASE & CO

pharmaceutical preparations

23.05M12.18%

12.18%

$3.32TNov 26, 2025 7.41M

DARWIN GLOBAL MANAGEMENT, LTD.

pharmaceutical preparations

20.46M9.66%

9.66%

$2.90TNov 14, 2025 1.11M

VANGUARD GROUP INC

pharmaceutical preparations

19.94M9.41%

9.41%

$2.87TNov 7, 2025 2.29M

BLACKROCK, INC.

pharmaceutical preparations

12.36M5.84%

5.84%

$1.78TNov 12, 2025 1.22M

FMR LLC

pharmaceutical preparations

9.18M4.34%

4.34%

$1.32TNov 13, 2025 4.09M

CAPITAL INTERNATIONAL INVESTORS

pharmaceutical preparations

7.55M3.57%

3.57%

$1.09TNov 13, 2025 75.0K

PRICE T ROWE ASSOCIATES INC /MD/

pharmaceutical preparations

6.93M3.27%

3.27%

$998.20BNov 14, 2025 4.30M

BAKER BROS. ADVISORS LP

pharmaceutical preparations

6.70M3.17%

3.17%

$965.37BNov 14, 2025 1.01M

D. E. SHAW & CO., INC.

pharmaceutical preparations

5.66M2.67%

2.67%

$814.73BNov 14, 2025 2.23M

ARTISAN PARTNERS LIMITED PARTNERSHIP

pharmaceutical preparations

4.94M2.33%

2.33%

$711.08BNov 12, 2025 1.62M

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBullish — more buying than selling

24

Increased

+27.52M shares

0

New Positions

first time holders

24

Decreased

−14.40M shares

0

Sold Out

fully exited

Net shares change (top 50)

+13.12M

+27.52M / −14.40M

Net new holders

+0

0 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

INSM insider trading · insider activity

Source: SEC Form 4

Buy 0%Active transactions only100% Sell

Insiders have been primarily selling shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

16

Buy transactions

45

Sell transactions

0.36

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Adsett Roger

Chief Operating Officer

Jun 3, 2026Sale2,370$102.27$242.4K98.6KForm 4 ↗

Bonstein Sara

Chief Financial Officer

Jun 3, 2026Sale2,404$102.27$245.9K69.1KForm 4 ↗

Smith Michael Alexander

Chief Legal Officer

Jun 3, 2026Sale2,159$102.27$220.8K39.5KForm 4 ↗

Lewis William

Chair and CEO

Jun 3, 2026Sale7,605$102.27$777.8K265.4KForm 4 ↗

Flammer Martina M.D.

Chief Medical Officer

Jun 3, 2026Sale2,566$102.27$262.4K62.3KForm 4 ↗

Flammer Martina M.D.

Chief Medical Officer

Jun 5, 2026Sale1,858$103.78$192.8K60.5KForm 4 ↗

Smith Michael Alexander

Chief Legal Officer

May 22, 2026Sale6,149$108.47$667.0K41.6KForm 4 ↗

Lewis William

Chair and CEO

May 18, 2026Sale5,753$105.32$605.9K292.8KForm 4 ↗

Lewis William

Chair and CEO

May 18, 2026Sale11,836$106.39$1.26M281.0KForm 4 ↗

Lewis William

Chair and CEO

May 18, 2026Sale7,975$106.97$853.1K273.0KForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Insmed Incorporated (INSM) is primarily owned by institutional investors, who hold approximately 97.3% of total shares outstanding. Company insiders own approximately 8.52%, while retail and public investors account for the remaining 0.00%.

The largest institutional shareholder of Insmed Incorporated is JPMORGAN CHASE & CO, holding approximately 23.05 million shares — equal to 12.18% of outstanding shares — as of September 30, 2025.

A total of 624 institutional investors currently hold INSM stock, with a combined institutional value of approximately $30.33 billion as of the most recent 13F filing period.

Frequently asked questions

INSM ownership

Insmed Incorporated (INSM) is primarily owned by institutional investors, who hold approximately 97.3% of shares. The largest shareholder is JPMORGAN CHASE & CO with a 12.18% stake. Company insiders hold 8.52%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns INSM stockINSM ownership structureSEC Form 13F institutional holdingsINSM float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025