Companies: 10,795·Total market cap: $144.5T
IO Biotech, Inc.

IO Biotech, Inc.

IOBTNASDAQHealthcare
$0.01
$-0.00(-27.59%)
Market Cap$885690
P/E Ratio
52W High$2.79
52W Low$0.01231

IO Biotech, Inc. (IOBT) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · IOBT · as of Sep 30, 2025

Ownership Breakdown

Institutions 13.75%
Insiders 16.12%
Public 70.12%

21

Institutional Holders

▼ 5 vs Q2

$3.59M

Total Inst. Value

▼ $21.68M vs Q2

71.95M

Shares Outstanding

freeFloat 83.88%

9.90M

13F Shares Held

▼ 8.29M vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

IOBT largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

NOVO HOLDINGS A/S

pharmaceutical preparations

2.51M3.81%

3.81%

$912.27MNov 14, 2025 842.0K

IKARIAN CAPITAL, LLC

pharmaceutical preparations

1.53M2.32%

2.32%

$554.05MNov 14, 2025NEW

MILLENNIUM MANAGEMENT LLC

pharmaceutical preparations

1.39M2.11%

2.11%

$505.58MNov 14, 2025NEW

MARSHALL WACE, LLP

pharmaceutical preparations

1.05M1.60%

1.60%

$378.95MNov 13, 2025 1.05M

BANK OF AMERICA CORP /DE/

pharmaceutical preparations

800.0K1.21%

1.21%

$290.38MFeb 3, 2026 815.1K

MORGAN STANLEY

pharmaceutical preparations

668.4K1.01%

1.01%

$242.70MMay 27, 2026 14.7K

BOOTHBAY FUND MANAGEMENT, LLC

pharmaceutical preparations

591.2K89.73%

89.73%

$214.66MNov 14, 2025NEW

RENAISSANCE TECHNOLOGIES LLC

pharmaceutical preparations

547.3K83.08%

83.08%

$198.73MNov 13, 2025 408.0K

POINT72 ASSET MANAGEMENT, L.P.

pharmaceutical preparations

250.0K37.95%

37.95%

$90.78MNov 14, 2025NEW

XTX TOPCO LTD

pharmaceutical preparations

179.2K27.20%

27.20%

$65.07MNov 14, 2025 150.0K

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBearish — more selling than buying

5

Increased

+575.2K shares

9

New Positions

first time holders

5

Decreased

−2.72M shares

14

Sold Out

fully exited

Net shares change (top 50)

2.14M

+575.2K / −2.72M

Net new holders

-5

9 new / 14 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

IOBT insider trading · insider activity

Source: SEC Form 4

Buy 71%Active transactions only29% Sell

Insiders have been net buyers of shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

12

Buy transactions

0

Sell transactions

0.00

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Smith David V

director

Jun 5, 2025Award35,144$1.50$52.7K35.1KForm 4 ↗

Hunter Heidi

director

Jun 5, 2025Award35,144$1.50$52.7K35.1KForm 4 ↗

Hirth Peter

director

Jun 5, 2025Award35,144$1.50$52.7K35.1KForm 4 ↗

Glaub Kathleen Sereda

director

Jun 5, 2025Award35,144$1.50$52.7K35.1KForm 4 ↗

Elling Christian E

director

Jun 5, 2025Award35,144$1.50$52.7K35.1KForm 4 ↗

Collins Helen Louise

director

Jun 5, 2025Award35,144$1.50$52.7K35.1KForm 4 ↗

Hunter Heidi

director

May 30, 2025Purchase15,000$1.39$20.9K15.0KForm 4 ↗

Zocca Mai-Britt

Chief Executive Officer

Apr 2, 2025Award580,000$1.07$620.6K580.0KForm 4 ↗

Sullivan Amy

Chief Financial Officer

Apr 2, 2025Award215,000$1.07$230.1K215.0KForm 4 ↗

Smith Devin Whittemore

General Counsel

Apr 2, 2025Award140,000$1.07$149.8K140.0KForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

IO Biotech, Inc. (IOBT) is primarily owned by institutional investors, who hold approximately 13.8% of total shares outstanding. Company insiders own approximately 16.12%, while retail and public investors account for the remaining 70.12%.

The largest institutional shareholder of IO Biotech, Inc. is NOVO HOLDINGS A/S, holding approximately 2.51 million shares — equal to 3.81% of outstanding shares — as of September 30, 2025.

A total of 21 institutional investors currently hold IOBT stock, with a combined institutional value of approximately $3,589,663 as of the most recent 13F filing period.

Frequently asked questions

IOBT ownership

IO Biotech, Inc. (IOBT) is primarily owned by institutional investors, who hold approximately 13.8% of shares. The largest shareholder is NOVO HOLDINGS A/S with a 3.81% stake. Company insiders hold 16.12%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns IOBT stockIOBT ownership structureSEC Form 13F institutional holdingsIOBT float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025