Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. (IONS) Insider Trading
Form 4 buy vs sell counts, ratio, and sentiment — switch this quarter or last 12 months; chart and transactions below.
SEC EDGAR · FMP · IONS · as of Jun 8, 2026
Activity summary
Buy transactions
0
P-Purchase only
Sell transactions
142
12 Months
Buy/Sell ratio
0.00
Buy/Sell (by trades)
Overall sentiment
Ionis Pharmaceuticals, Inc. insiders have been primarily selling shares over the past 12 Months. Selling activity is often driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment toward the company.
▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · Buy = P-Purchase only · Sell = S-Sale only
As of Jun 8, 2026
IONS insider buying and selling by quarter
IONS insider selling · IONS insider buying stocks · quarterly insider activity
Mobile shows last 4Q · Desktop shows full 8Q
▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · last 8 quarters
As of Jun 8, 2026
Active insiders
Most active in past 12 months · IONS ceo insider trading
Showing all insiders · Click a card to filter the transactions table below
▸ Aggregated from reportingName · top 5 by trade count (12M) · no extra API
Recent insider transactions
IONS executive sell shares · IONS board member insider trading · IONS insider trading SEC filing
Scroll horizontally to see all columns
| Date | Insider | Type | Shares | Value | Filing |
|---|---|---|---|---|---|
| Jun 1, 2026 | BERTHELSEN SPENCER R Director | Option | 8,000 | $195K | Form 4 |
| Jun 1, 2026 | BERTHELSEN SPENCER R Director | Sale | 8,000 | $605K | Form 4 |
| May 14, 2026 | Monia Brett P CEO · Director | Option | 3,220 | $105K | Form 4 |
| May 13, 2026 | Monia Brett P CEO · Director | Option | 1,316 | $43K | Form 4 |
| May 13, 2026 | Monia Brett P CEO · Director | Sale | 1,316 | $103K | Form 4 |
| May 14, 2026 | Monia Brett P CEO · Director | Sale | 3,220 | $253K | Form 4 |
| May 4, 2026 | LOSCALZO JOSEPH Director | Option | 16,000 | $1.04M⚡ | Form 4 |
| May 4, 2026 | LOSCALZO JOSEPH Director | Option | 12,000 | $722K | Form 4 |
| May 4, 2026 | LOSCALZO JOSEPH Director | Option | 16,000 | $686K | Form 4 |
| May 4, 2026 | LOSCALZO JOSEPH Director | Option | 10,321 | $424K | Form 4 |
| May 4, 2026 | LOSCALZO JOSEPH Director | Option | 12,000 | $481K | Form 4 |
| May 4, 2026 | LOSCALZO JOSEPH Director | Sale | 59,508 | $4.46M⚡ | Form 4 |
| May 4, 2026 | LOSCALZO JOSEPH Director | Option | 10,968 | $417K | Form 4 |
| May 4, 2026 | LOSCALZO JOSEPH Director | Sale | 17,781 | $1.34M⚡ | Form 4 |
| May 1, 2026 | KLEIN JOSEPH III Director | Option | 10,111 | $476K | Form 4 |
| May 1, 2026 | KLEIN JOSEPH III Director | Sale | 8,680 | $637K | Form 4 |
| May 1, 2026 | KLEIN JOSEPH III Director | Sale | 1,431 | $107K | Form 4 |
| Apr 28, 2026 | Baroldi Joseph EVP, Chief Business Officer | Sale | 1,626 | $117K | Form 4 |
| Apr 15, 2026 | PARSHALL B LYNNE Director | Sale | 4,466 | $340K | Form 4 |
| Apr 15, 2026 | PARSHALL B LYNNE Director | Sale | 534 | $41K | Form 4 |
| Apr 15, 2026 | Jenne Kyle EVP, Chf GL Pdt Str Ofcr | Option | 12,226 | — | Form 4 |
| Apr 16, 2026 | Jenne Kyle EVP, Chf GL Pdt Str Ofcr | Sale | 4,902 | $368K | Form 4 |
| Apr 15, 2026 | Birchler Brian EVP, Corp and Development Ops | Option | 1,875 | — | Form 4 |
| Apr 16, 2026 | Birchler Brian EVP, Corp and Development Ops | Sale | 973 | $73K | Form 4 |
| Apr 15, 2026 | Baroldi Joseph EVP, Chief Business Officer | Option | 10,837 | — | Form 4 |
Baroldi Joseph
EVP, Chief Business Officer
Date
Apr 28
Shares
1,626
Price
$71.79
Value
$117K
Jenne Kyle
EVP, Chf GL Pdt Str Ofcr
Date
Apr 16
Shares
4,902
Price
$75.17
Value
$368K
Birchler Brian
EVP, Corp and Development Ops
Date
Apr 15
Shares
1,875
Price
—
Value
—
Birchler Brian
EVP, Corp and Development Ops
Date
Apr 16
Shares
973
Price
$75.04
Value
$73K
Baroldi Joseph
EVP, Chief Business Officer
Date
Apr 15
Shares
10,837
Price
—
Value
—
⚡ = value ≥ $1M · Award/Option price shows — · formType=4 · securityName=Common Stock · url → sec.gov/Archives/edgar
▸ Source: SEC EDGAR · Form 4 filings · ⚡ = value ≥ $1M · Award/Option price shows —
About IONS insider trading
IONS insider trades
Ionis Pharmaceuticals, Inc. (IONS) insider trading data is sourced from SEC Form 4 filings submitted by corporate insiders, including LOSCALZO JOSEPH (Director), KLEIN JOSEPH III (Director), Devers Shannon L. (EVP, Chief Human Resources Ofc). Over the past 12 months, 5 insiders have filed transactions with the SEC. IONS insiders have been primarily selling, which may reflect pre-scheduled Rule 10b5-1 plan executions.
For Ionis Pharmaceuticals, Inc.'s institutional ownership breakdown and insider ownership percentage, see the Ownership tab → Ownership tab →
Frequently asked questions
IONS insider trading · 5 questionsThe insiders of Ionis Pharmaceuticals, Inc. (IONS) include executives and directors such as LOSCALZO JOSEPH (Director), KLEIN JOSEPH III (Director), Devers Shannon L. (EVP, Chief Human Resources Ofc), among others. Over the past 12 months, 5 insiders have filed Form 4 transactions with the SEC. Insider transactions are required to be reported within 2 business days of the trade date.
▸ Source: FMP /stable/insider-trading/search · SEC EDGAR Form 3 & 4 · acquisitionOrDisposition A=Buy, D=Sell · RSU vesting (M-Exempt) excluded from sentiment bar · As of Jun 8, 2026