Companies: 10,795·Total market cap: $144.5T
Krystal Biotech, Inc.

Krystal Biotech, Inc.

KRYSNASDAQHealthcare● Active
$302.27
+$1.27(+0.42%)
Market Cap$8.9B
P/E Ratio
52W High$319.48
52W Low$127.99

Krystal Biotech, Inc. (KRYS) PE Ratio — Current & Historical Data

Trailing twelve months (TTM) P/E, forward P/E, PEG, and annual PE history — from market prices and filings.

krys · pe ratio · data through Dec 31, 2025

Core PE Ratio Metrics

Trailing 12 months · TTM

The price-to-earnings (P/E) ratio for Krystal Biotech, Inc. (KRYS) measures how much investors pay for each dollar of the company's trailing earnings. KRYS's current PE ratio of 39.52x is calculated by dividing its stock price of $302.27 by its TTM earnings per share of $7.68. −69.8% discount vs 5Y avg 131.1x

39.52x
P/E Ratio (TTM)69.8%

Source: FMP · /ratios-ttm · /analyst-estimates · 2025-12-31

Forward P/E
31.13x
FY2027 est. EPS $9.71
Based on 7 analysts
EPS (TTM)
$7.68
TTM · diluted EPS
PEG Ratio
0.50
Below 1.0 · Growth adjusted
Source: FMP · /ratios-ttm · /ratios annual · /analyst-estimates · /stock-peers · Krystal Biotech, Inc. SEC 10-K & 10-Q filings · US GAAPUpdated: 2026-06-08

PE Ratio History

2016 – 2025 · Annual
PE Ratio (TTM)
5Y Avg 131.1x
EPS (Annual)

▸ FMP /ratios?period=annual&limit=20 · priceToEarningsRatio + netIncomePerShare (Annual)

Historical PE Range

Past 3 fiscal years · Front-end computed
Average
131.1x
3-yr mean
Median
50.2x
3-yr midpoint
Minimum
34.8x
Lowest year
Maximum
308.2x
Highest year
39.5x ← Now
34.8x
Min
Q1 · 25%50.2x
Median
Q3 · 75%308.2x
Max
Within Historical Range

At 39.52x, KRYS's current P/E is within its average historical range over the past 3 fiscal years.

33th percentileHigher than 1 of 3 historical fiscal year readings

Percentile calculated from annual fiscal year data points, not by trading day. Years where PE ≤ 0 or > 9,999 are excluded.

PE Ratio vs Peers

Biotechnology · 6 peers · Annual PE
CompanyMarket CapPE (Annual)vs AvgEPS (TTM)
Krystal Biotech, Inc.
Krystal Biotech, Inc.You
KRYS
$8.9B39.52x$7.68
Arcellx, Inc.
Arcellx, Inc.
ACLX
$6.7BN/A-$4.07
Alkermes plc
Alkermes plc
ALKS
$7.1B19.07x$1.47
Arrowhead Pharmaceuticals, Inc.
Arrowhead Pharmaceuticals, Inc.
ARWR
$10.4BN/A-$0.01
CRISPR Therapeutics AG
CRISPR Therapeutics AG
CRSP
$4.9BN/A-$6.47
Metsera, Inc.
Metsera, Inc.
MTSR
$7.4BN/A-$2.03
Vaxcyte, Inc.
Vaxcyte, Inc.
PCVX
$6.7BN/A-$5.63

* N/A — Company is not profitable (TTM) · excluded from industry average · ▸ FMP /stock-peers + /ratios?limit=1 · priceToEarningsRatio

Annual PE Ratio History

Showing 10 of 10 years
Fiscal Year EndPE RatioEPS (TTM)YoY ChangePE vs Max
2025-12-31Latest
FY2025
34.84x$7.08-30.7%
2024-12-31
FY2024
50.24x$3.12-83.7%
2023-12-31
FY2023
308.15x$0.40
2022-12-31
FY2022
$-5.49
2021-12-31
FY2021
$-3.13
2020-12-31
FY2020
$-1.71
2019-12-31
FY2019
$-1.20
2018-12-31
FY2018
$-0.97
2017-12-31
FY2017
$-1.48
2016-12-31
FY2016
$-0.27

▸ FMP /ratios?period=annual&limit=20 · priceToEarningsRatio + netIncomePerShare · Zero extra API

About PE Ratio & Methodology

The price-to-earnings (P/E) ratio for Krystal Biotech, Inc. (KRYS) measures how much investors pay for each dollar of the company's trailing earnings. KRYS's current PE ratio of 39.52x is calculated by dividing its stock price of $302.27 by its TTM earnings per share of $7.68.

PE Ratio = Stock Price ÷ EPS (TTM)
= $302.27 ÷ $7.68 = 39.52x
TTMTrailing Twelve Months — sum of the most recent 4 quarterly EPS figures
Forward PEStock price ÷ analyst consensus EPS estimate for the next fiscal year
PEGPE ÷ earnings growth rate — values below 1.0 suggest growth may justify the premium
Figures tie to SEC 10-K/10-Q and FMP ratio endpoints where noted.

Frequently asked questions

KRYS pe ratio · 6 questions

KRYS's current PE ratio is 39.52x as of 2026-06-08, based on a stock price of $302.27 and TTM EPS of $7.68. Data sourced from Financial Modeling Prep via KRYS's SEC 10-K and 10-Q filings.

KRYS PE ratioWhat is KRYS PE ratioCurrent PE ratio of KRYSKRYS PE ratio today

Source: FMP · /ratios-ttm · /ratios annual · /analyst-estimates · /stock-peers · Krystal Biotech, Inc. SEC 10-K & 10-Q filings · US GAAP · Updated: 2026-06-08