Companies: 10,795·Total market cap: $144.5T
Madrigal Pharmaceuticals, Inc.

Madrigal Pharmaceuticals, Inc.

MDGLNASDAQHealthcare● Active
$486.98
$-5.85(-1.19%)
Market Cap$11.2B
P/E Ratio
52W High$615
52W Low$271.96

Madrigal Pharmaceuticals, Inc. (MDGL) Net Income & Profit History

Annual & trailing net income, net margin, YoY change, and peer profitability context.

MDGL · net income · updated Jun 8, 2026

Core profitability metrics

Net income was −$288.3M for FY2025 (fiscal year ending 2025-12-31), up 38.1% year-over-year. Net profit margin was -30.1%.

FY2025 Net Income−$288.3M▲ +38.1% YoY
Trailing 12M (TTM)−$309.4Mtrailing 4 quarters sum
Net Profit Margin-30.1%−$288.3M ÷ $958.4M
YoY Change+38.1%
5-Year CAGRN/AN/A — contains loss years
FormulaNet Margin = Net Income ÷ Revenue × 100TTM = trailing 4 quarters sumCAGR → N/A if either endpoint ≤ 0
Source: FMP /income-statement · US GAAP · USDUpdated: Jun 8, 2026

Annual net income history

Net IncomeNet LossNet Margin %

▸ FMP /income-statement · Annual · MDGL net income history · MDGL profit margin

Annual net income data

Fiscal YearNet IncomeYoY ChangeNet Margin
FY2025Loss−$288.3M▲ +38.1%-30.1%
FY2024Loss−$465.9M▼ 24.7%-258.6%
FY2023Loss−$373.6M▼ 26.5%
FY2022Loss−$295.4M▼ 22.1%
FY2021Loss−$241.8M▼ 19.6%

Net income vs peers (Healthcare)

#CompanyNet IncomeYoY
#1
Madrigal Pharmaceuticals, Inc.
Madrigal Pharmaceuticals, Inc.YOU
MDGL
−$288.3M+38.1%
#2
Johnson & Johnson
Johnson & Johnson
JNJ
$26.80B+90.6%
#3
Eli Lilly and Company
Eli Lilly and Company
LLY
$20.64B+94.9%
#4
UnitedHealth Group Incorporated
UnitedHealth Group Incorporated
UNH
$12.06B-16.3%
#5
AbbVie Inc.
AbbVie Inc.
ABBV
$4.23B-1.2%
Healthcare · Sorted by Net Income · FMP /income-statementFull Net Income Rankings →

About Net Income & Methodology

Madrigal Pharmaceuticals, Inc. (MDGL) reported net income of −$288.3M for FY2025 (fiscal year ending 2025-12-31), up 38.1% year-over-year. The net profit margin was -30.1% — meaning the company kept $-0.30 of every dollar of revenue as profit.

Madrigal Pharmaceuticals, Inc. has not yet achieved annual profitability based on available data (15 fiscal years). The company has reported net losses across all available periods.

Madrigal Pharmaceuticals, Inc.'s net profit margin was -30.1% for FY2025, based on the latest annual results.

Investors sometimes search for "Madrigal Pharmaceuticals, Inc. net worth" — the company's market capitalization is a separate figure from MDGL net income. Data sourced from FMP /income-statement · US GAAP · USD.

Figures tie to SEC 10-K/10-Q and FMP /income-statement where noted.

Frequently asked questions

MDGL net income · 4 questions

Madrigal Pharmaceuticals, Inc. is not currently profitable on an annual basis. The company reported a net loss of $288.3M for FY2025.

is MDGL profitabledoes MDGL make a profitMDGL profitabilityMDGL profitable company

Source: FMP /income-statement · GAAP · Madrigal Pharmaceuticals, Inc. · Madrigal Pharmaceuticals, Inc. SEC 10-K & 10-Q filings · US GAAP · Last updated: Jun 8, 2026