Companies: 10,795·Total market cap: $144.5T
ProQR Therapeutics N.V.

ProQR Therapeutics N.V.

PRQRNASDAQHealthcare● Active
$1.53
+$0.03(+2.00%)
Market Cap$161202330
P/E Ratio
52W High$3.1
52W Low$1.33

ProQR Therapeutics N.V. (PRQR) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · PRQR · as of Sep 30, 2025

Ownership Breakdown

Institutions 35.63%
Insiders 38.93%
Public 25.44%

64

Institutional Holders

$79.97M

Total Inst. Value

▼ $2.42M vs Q2

105.36M

Shares Outstanding

freeFloat 61.07%

37.54M

13F Shares Held

▼ 2.92M vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

PRQR largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

ADAGE CAPITAL PARTNERS GP, L.L.C.

pharmaceutical preparations

6.25M5.94%

5.94%

$13.32BNov 14, 2025 348.5K

PRIVIUM FUND MANAGEMENT B.V.

pharmaceutical preparations

5.00M4.74%

4.74%

$10.65BNov 4, 2025 725

AFFINITY ASSET ADVISORS, LLC

pharmaceutical preparations

3.60M3.42%

3.42%

$7.67BNov 13, 2025 100.5K

MORGAN STANLEY

pharmaceutical preparations

2.90M2.75%

2.75%

$6.18BMay 27, 2026 182.3K

ABRDN PLC

pharmaceutical preparations

2.30M2.18%

2.18%

$4.90BNov 7, 2025 448.5K

SIO CAPITAL MANAGEMENT, LLC

pharmaceutical preparations

2.08M1.97%

1.97%

$4.42BNov 13, 2025— held

KYNAM CAPITAL MANAGEMENT, LP

pharmaceutical preparations

1.65M1.57%

1.57%

$3.51BNov 14, 2025— held

DAFNA CAPITAL MANAGEMENT LLC

pharmaceutical preparations

1.57M1.49%

1.49%

$3.34BNov 14, 2025— held

SIREN, L.L.C.

pharmaceutical preparations

1.55M1.47%

1.47%

$3.31BNov 13, 2025— held

ARROWMARK COLORADO HOLDINGS LLC

pharmaceutical preparations

1.25M1.18%

1.18%

$2.65BNov 14, 2025 46.6K

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBullish — more buying than selling

16

Increased

+1.35M shares

4

New Positions

first time holders

9

Decreased

−4.40M shares

0

Sold Out

fully exited

Net shares change (top 50)

3.05M

+1.35M / −4.40M

Net new holders

+11

4 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

PRQR insider trading · insider activity

Source: SEC Form 4

0

Buy transactions

0

Sell transactions

0.00

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

No recent insider transactions reported.

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

ProQR Therapeutics N.V. (PRQR) is primarily owned by institutional investors, who hold approximately 35.6% of total shares outstanding. Company insiders own approximately 38.93%, while retail and public investors account for the remaining 25.44%.

The largest institutional shareholder of ProQR Therapeutics N.V. is ADAGE CAPITAL PARTNERS GP, L.L.C., holding approximately 6.25 million shares — equal to 5.94% of outstanding shares — as of September 30, 2025.

A total of 64 institutional investors currently hold PRQR stock, with a combined institutional value of approximately $79,967,133 as of the most recent 13F filing period.

Frequently asked questions

PRQR ownership

ProQR Therapeutics N.V. (PRQR) is primarily owned by institutional investors, who hold approximately 35.6% of shares. The largest shareholder is ADAGE CAPITAL PARTNERS GP, L.L.C. with a 5.94% stake. Company insiders hold 38.93%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns PRQR stockPRQR ownership structureSEC Form 13F institutional holdingsPRQR float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025