Prothena Corporation plc

PRTANASDAQHealthcare● Active

$8.56

$-0.23(-2.62%)

Market Cap$448143709

P/E Ratio—

52W High$11.8

52W Low$4.95

Avg Volume521K

Open$8.80

Beta-0.32

Net Income Financials Revenue

Prothena Corporation plc (PRTA) Net Income & Profit History

Annual & trailing net income, net margin, YoY change, and peer profitability context.

PRTA · net income · updated Jun 8, 2026

Core profitability metrics

PRTA · net income · margin · TTM · CAGR

Net income was −$244.1M for FY2025 (fiscal year ending 2025-12-31), down 99.6% year-over-year. Net profit margin was -2520.6%. Based on available data, Prothena Corporation plc has been profitable since at least 2021.

FY2025 Net Income−$244.1M▼ -99.6% YoY

Trailing 12M (TTM)−$151.2Mtrailing 4 quarters sum

Net Profit Margin< −999%−$244.1M ÷ $9.7M

YoY Change-99.6%—

5-Year CAGRN/AN/A — contains loss years

FormulaNet Margin = Net Income ÷ Revenue × 100TTM = trailing 4 quarters sumCAGR → N/A if either endpoint ≤ 0

Source: FMP /income-statement · US GAAP · USDUpdated: Jun 8, 2026

Annual net income history

Net Income (bars) · Net Profit Margin % (line)

Net IncomeNet LossNet Margin %★ First Profit: 2021

▸ FMP /income-statement · Annual · PRTA net income history · PRTA profit margin

Annual net income data

PRTA · net income history · annual / quarterly

Fiscal YearNet IncomeYoY ChangeNet MarginRevenue

FY2025Loss−$244.1M▼ 99.6%-2520.6%$9.7M

FY2024Loss−$122.3M▲ +16.8%-90.5%$135.2M

FY2023Loss−$147.0M▼ 25.7%-160.9%$91.4M

FY2022Loss−$116.9M▼ 274.6%-216.9%$53.9M

FY2021★ First Profit$67.0M▲ +160.3%33.4%$200.6M

Net income vs peers (Healthcare)

PRTA vs peers · net income

#CompanyNet IncomeYoYNet MarginRelative

Prothena Corporation plcYOU

PRTA

−$244.1M-99.6%-2520.6%

Loss

Eli Lilly and Company

LLY

$20.64B+94.9%31.7%

77%

UnitedHealth Group Incorporated

Healthcare · Sorted by Net Income · FMP /income-statementFull Net Income Rankings →

About Net Income & Methodology

Prothena Corporation plc (PRTA) reported net income of −$244.1M for FY2025 (fiscal year ending 2025-12-31), down 99.6% year-over-year. The net profit margin was -2520.6% — meaning the company kept $-25.21 of every dollar of revenue as profit.

Based on available data, Prothena Corporation plc has been profitable since at least 2021. Net income reached a peak of $67.0M in FY2021. Data available for 15 fiscal years.

Prothena Corporation plc's net profit margin was -2520.6% for FY2025, based on the latest annual results.

Investors sometimes search for "Prothena Corporation plc net worth" — the company's market capitalization is a separate figure from PRTA net income. Data sourced from FMP /income-statement · US GAAP · USD.

Figures tie to SEC 10-K/10-Q and FMP /income-statement where noted.

Revenue Financial statements Earnings Forecast Price history Market cap Free cash flow

Frequently asked questions

PRTA net income · 4 questions

Prothena Corporation plc is not currently profitable on an annual basis. The company reported a net loss of $244.1M for FY2025.

is PRTA profitabledoes PRTA make a profitPRTA profitabilityPRTA profitable company

▸ Source: FMP /income-statement · GAAP · Prothena Corporation plc · Prothena Corporation plc SEC 10-K & 10-Q filings · US GAAP · Last updated: Jun 8, 2026