Companies: 10,795·Total market cap: $144.5T
Soleno Therapeutics, Inc.

Soleno Therapeutics, Inc.

SLNONASDAQHealthcare
$53.01
+$0.00(+0.00%)
Market Cap$2.8B
P/E Ratio
52W High$90.3199
52W Low$29.43

Soleno Therapeutics, Inc. (SLNO) PE Ratio — Current & Historical Data

Trailing twelve months (TTM) P/E, forward P/E, PEG, and annual PE history — from market prices and filings.

slno · pe ratio · data through Dec 31, 2025

Core PE Ratio Metrics

Trailing 12 months · TTM

The price-to-earnings (P/E) ratio for Soleno Therapeutics, Inc. (SLNO) measures how much investors pay for each dollar of the company's trailing earnings. SLNO's current PE ratio of 28.75x is calculated by dividing its stock price of $53.01 by its TTM earnings per share of $1.84. −75.6% discount vs 5Y avg 117.9x

28.75x
P/E Ratio (TTM)75.6%

Source: FMP · /ratios-ttm · /analyst-estimates · 2025-12-31

Forward P/E
8.63x
FY2027 est. EPS $6.14
Based on 6 analysts
EPS (TTM)
$1.84
TTM · diluted EPS
PEG Ratio
0.02
Below 1.0 · Growth adjusted
Source: FMP · /ratios-ttm · /ratios annual · /analyst-estimates · /stock-peers · Soleno Therapeutics, Inc. SEC 10-K & 10-Q filings · US GAAPUpdated: 2026-06-08

PE Ratio History

2012 – 2025 · Annual
PE Ratio (TTM)
5Y Avg 117.9x
EPS (Annual)

▸ FMP /ratios?period=annual&limit=20 · priceToEarningsRatio + netIncomePerShare (Annual)

PE Ratio vs Peers

Biotechnology · 6 peers · Annual PE
CompanyMarket CapPE (Annual)vs AvgEPS (TTM)
Soleno Therapeutics, Inc.
Soleno Therapeutics, Inc.You
SLNO
$2.8B28.75x$1.84
Ascentage Pharma Group International
Ascentage Pharma Group International
AAPG
$1.6BN/A-$13.58
Apogee Therapeutics, Inc.
Apogee Therapeutics, Inc.
APGE
$5.1BN/A-$4.22
Celcuity Inc.
Celcuity Inc.
CELC
$4.2BN/A-$3.37
Centessa Pharmaceuticals plc
Centessa Pharmaceuticals plc
CNTA
$6.1BN/A-$1.46
Dyne Therapeutics, Inc.
Dyne Therapeutics, Inc.
DYN
$2.8BN/A-$3.47
Mirum Pharmaceuticals, Inc.
Mirum Pharmaceuticals, Inc.
MIRM
$4.7BN/A-$0.47

* N/A — Company is not profitable (TTM) · excluded from industry average · ▸ FMP /stock-peers + /ratios?limit=1 · priceToEarningsRatio

Annual PE Ratio History

Showing 10 of 14 years
Fiscal Year EndPE RatioEPS (TTM)YoY ChangePE vs Max
2025-12-31Latest
FY2025
117.86x$0.39
2024-12-31
FY2024
$-4.38
2023-12-31
FY2023
$-2.36
2022-12-31
FY2022
$-2.87
2021-12-31
FY2021
$-5.81
2020-12-31
FY2020
$-5.90
2019-12-31
FY2019
$-13.52
2018-12-31
FY2018
$-9.54
2017-12-31
FY2017
$-26.18
2016-12-31
FY2016
$-58.35

▸ FMP /ratios?period=annual&limit=20 · priceToEarningsRatio + netIncomePerShare · Zero extra API

About PE Ratio & Methodology

The price-to-earnings (P/E) ratio for Soleno Therapeutics, Inc. (SLNO) measures how much investors pay for each dollar of the company's trailing earnings. SLNO's current PE ratio of 28.75x is calculated by dividing its stock price of $53.01 by its TTM earnings per share of $1.84.

PE Ratio = Stock Price ÷ EPS (TTM)
= $53.01 ÷ $1.84 = 28.75x
TTMTrailing Twelve Months — sum of the most recent 4 quarterly EPS figures
Forward PEStock price ÷ analyst consensus EPS estimate for the next fiscal year
PEGPE ÷ earnings growth rate — values below 1.0 suggest growth may justify the premium
Figures tie to SEC 10-K/10-Q and FMP ratio endpoints where noted.

Frequently asked questions

SLNO pe ratio · 6 questions

SLNO's current PE ratio is 28.75x as of 2026-06-08, based on a stock price of $53.01 and TTM EPS of $1.84. Data sourced from Financial Modeling Prep via SLNO's SEC 10-K and 10-Q filings.

SLNO PE ratioWhat is SLNO PE ratioCurrent PE ratio of SLNOSLNO PE ratio today

Source: FMP · /ratios-ttm · /ratios annual · /analyst-estimates · /stock-peers · Soleno Therapeutics, Inc. SEC 10-K & 10-Q filings · US GAAP · Updated: 2026-06-08