Companies: 10,795·Total market cap: $144.5T
Summit Therapeutics Inc.

Summit Therapeutics Inc.

SMMTNASDAQHealthcare● Active
$14.11
$-0.66(-4.47%)
Market Cap$10.9B
P/E Ratio
52W High$30.98
52W Low$13.8101

Summit Therapeutics Inc. (SMMT) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · SMMT · as of Sep 30, 2025

Ownership Breakdown

Institutions 13.27%
Insiders 86.17%
Public 0.56%

257

Institutional Holders

▲ 5 vs Q2

$2.12B

Total Inst. Value

▲ $44.35M vs Q2

775.37M

Shares Outstanding

freeFloat 13.83%

102.88M

13F Shares Held

▲ 5.02M vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

SMMT largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

BAKER BROS. ADVISORS LP

pharmaceutical preparations

33.72M4.54%

4.54%

$696.72BNov 14, 2025— held

VANGUARD GROUP INC

pharmaceutical preparations

11.38M1.53%

1.53%

$235.11BNov 7, 2025 2.71M

FMR LLC

pharmaceutical preparations

8.92M1.20%

1.20%

$184.24BNov 13, 2025 308.5K

BLACKROCK, INC.

pharmaceutical preparations

7.36M99.16%

99.16%

$152.14BNov 12, 2025 517.1K

STATE STREET CORP

pharmaceutical preparations

6.36M85.67%

85.67%

$131.44BNov 14, 2025 2.34M

PRICE T ROWE ASSOCIATES INC /MD/

pharmaceutical preparations

4.54M61.12%

61.12%

$93.77BNov 14, 2025 633.7K

GEODE CAPITAL MANAGEMENT, LLC

pharmaceutical preparations

3.13M42.19%

42.19%

$64.74BNov 12, 2025 197.9K

MORGAN STANLEY

pharmaceutical preparations

1.93M25.95%

25.95%

$39.81BMay 27, 2026 1.28M

PICTET ASSET MANAGEMENT HOLDING SA

pharmaceutical preparations

1.60M21.60%

21.60%

$33.50BNov 18, 2025 559.7K

SUSQUEHANNA INTERNATIONAL GROUP, LLP

pharmaceutical preparations

1.39M18.74%

18.74%

$28.75BNov 14, 2025 345.4K

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBullish — more buying than selling

30

Increased

+11.67M shares

4

New Positions

first time holders

11

Decreased

−2.86M shares

0

Sold Out

fully exited

Net shares change (top 50)

+8.81M

+11.67M / −2.86M

Net new holders

+23

4 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

SMMT insider trading · insider activity

Source: SEC Form 4

Buy 100%Active transactions only0% Sell

Insiders have been net buyers of shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

4

Buy transactions

0

Sell transactions

0.00

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

DUGGAN ROBERT W

Co-Chief Executive Officer

Jun 4, 2026Purchase100,000$14.60$1.46M25.82MForm 4 ↗

Zanganeh Mahkam

Co-Chief Executive Officer

Jun 4, 2026Purchase100,000$14.60$1.46M25.82MForm 4 ↗

Soni Manmeet Singh

COO and CFO

Jun 4, 2026Purchase25,000$14.43$360.8K3.12MForm 4 ↗

Soni Manmeet Singh

COO and CFO

Jun 4, 2026Purchase25,000$14.46$361.5K3.10MForm 4 ↗

Anand Bhaskar

Chief Accounting Officer

Jan 8, 2026Award30,000$18.83$564.9K30.0KForm 4 ↗

Zanganeh Mahkam

Co-Chief Executive Officer

Jan 2, 2026Award11,232$17.52$196.8K11.2KForm 4 ↗

DUGGAN ROBERT W

Co-Chief Executive Officer

Jan 2, 2026Award11,232$17.52$196.8K11.2KForm 4 ↗

Booth Robert F.

director

Jan 2, 2026Award35,000$17.52$613.2K35.0KForm 4 ↗

Booth Robert F.

director

Jan 2, 2026Award7,180$17.52$125.8K7.2KForm 4 ↗

Xia Yu

director

Jan 2, 2026Award35,000$17.52$613.2K35.0KForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Summit Therapeutics Inc. (SMMT) is primarily owned by institutional investors, who hold approximately 13.3% of total shares outstanding. Company insiders own approximately 86.17%, while retail and public investors account for the remaining 0.56%.

The largest institutional shareholder of Summit Therapeutics Inc. is BAKER BROS. ADVISORS LP, holding approximately 33.72 million shares — equal to 4.54% of outstanding shares — as of September 30, 2025.

A total of 257 institutional investors currently hold SMMT stock, with a combined institutional value of approximately $2.12 billion as of the most recent 13F filing period.

Frequently asked questions

SMMT ownership

Summit Therapeutics Inc. (SMMT) is primarily owned by institutional investors, who hold approximately 13.3% of shares. The largest shareholder is BAKER BROS. ADVISORS LP with a 4.54% stake. Company insiders hold 86.17%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns SMMT stockSMMT ownership structureSEC Form 13F institutional holdingsSMMT float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025