Spruce Biosciences, Inc.
Spruce Biosciences, Inc. (SPRB) Stock Ownership
Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.
SEC 13F · FMP · SPRB · as of Sep 30, 2025
Ownership Breakdown
9
Institutional Holders
▲ 6 vs Q2
$25.14M
Total Inst. Value
▲ $24.99M vs Q2
1.37M
Shares Outstanding
freeFloat 66.24%
2.94M
13F Shares Held
▲ 891,067 vs Q2
Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.
Top Institutional Holders
SPRB largest shareholders · institutional ownership
Q3 2025 · SEC 13F
Showing top 10 holders
| Holder | Shares | % Owned | Weight | Value | Reported | Change |
|---|---|---|---|---|---|---|
CARLYLE GROUP INC. pharmaceutical preparations | 2.90M | 514.42% | 514.42% | $24.77B | Nov 7, 2025 | NEW |
CABLE CAR CAPITAL LLC pharmaceutical preparations | 26.7K | 4.74% | 4.74% | $238.66M | Nov 14, 2025 | NEW |
IKARIAN CAPITAL, LLC pharmaceutical preparations | 13.3K | 2.37% | 2.37% | $119.32M | Nov 14, 2025 | NEW |
LION POINT CAPITAL, LP pharmaceutical preparations | 1.0K | 17.76% | 17.76% | $8.95M | Nov 14, 2025 | NEW |
ADVISOR GROUP HOLDINGS, INC. pharmaceutical preparations | 133 | 2.36% | 2.36% | $931,000 | Nov 14, 2025 | NEW |
UBS GROUP AG pharmaceutical preparations | 132 | 2.34% | 2.34% | $1.18M | Nov 13, 2025 | NEW |
MORGAN STANLEY pharmaceutical preparations | 98 | 1.74% | 1.74% | $878,000 | May 27, 2026 | NEW |
CALDWELL SUTTER CAPITAL, INC. pharmaceutical preparations | 13 | 0.23% | 0.23% | $116,000 | Oct 29, 2025 | NEW |
BANK OF AMERICA CORP /DE/ pharmaceutical preparations | 3 | 0.05% | 0.05% | $27,000 | Feb 3, 2026 | NEW |
ACADIAN ASSET MANAGEMENT LLC pharmaceutical preparations | 0 | 0.00% | 0.00% | $0 | Nov 13, 2025 | EXIT |
Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).
Institutional Activity
Q3 2025 vs prior quarter
Q3 2025
0
Increased
+0 shares9
New Positions
first time holders0
Decreased
−0 shares3
Sold Out
fully exitedNet shares change (top 50)
+0
+0 / −0
Net new holders
+6
9 new / 3 exited
Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).
Insider Buying vs Selling
SPRB insider trading · insider activity
Source: SEC Form 4
1
Buy transactions
0
Sell transactions
0.00
Buy/Sell ratio
$0M
Total disposed
Recent Insider Transactions
Showing 10 most recent · Common Stock only
| Name · Role | Date | Type | Shares | Price | Value | After Trans. | Filing |
|---|---|---|---|---|---|---|---|
SPIEGELMAN DANIEL K director | May 21, 2026 | Award | 1,700 | $52.70 | $89.6K | 1.7K | Form 4 ↗ |
SIMPSON CAMILLA V director | May 21, 2026 | Award | 1,700 | $52.70 | $89.6K | 1.7K | Form 4 ↗ |
GREY MICHAEL G Executive Chairman | May 21, 2026 | Award | 1,700 | $52.70 | $89.6K | 1.7K | Form 4 ↗ |
Barretto-Ko Percival director | May 21, 2026 | Award | 1,700 | $52.70 | $89.6K | 1.7K | Form 4 ↗ |
Walbert Keli director | May 21, 2026 | Award | 1,700 | $52.70 | $89.6K | 1.7K | Form 4 ↗ |
Hooks Corwin Dale Chief Commercial Officer | Mar 9, 2026 | Award | 11,000 | — | — | 11.0K | Form 4 ↗ |
Ways Douglas Kirk Interim Chief Medical Officer | Dec 11, 2025 | Award | 5,000 | — | — | 5.0K | Form 4 ↗ |
Ways Douglas Kirk Interim Chief Medical Officer | Dec 11, 2025 | Award | 400 | $104.13 | $41.7K | 400 | Form 4 ↗ |
Ways Douglas Kirk Interim Chief Medical Officer | Dec 11, 2025 | Award | 266 | $104.13 | $27.7K | 266 | Form 4 ↗ |
Ways Douglas Kirk Interim Chief Medical Officer | Dec 11, 2025 | D-Return | 400 | $169.50 | $67.8K | 0 | Form 4 ↗ |
Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.
About institutional & insider ownership
Spruce Biosciences, Inc. (SPRB) is primarily owned by institutional investors, who hold approximately 100.0% of total shares outstanding. Company insiders own approximately 33.76%, while retail and public investors account for the remaining 0.00%.
The largest institutional shareholder of Spruce Biosciences, Inc. is CARLYLE GROUP INC., holding approximately 2.90 million shares — equal to 514.42% of outstanding shares — as of September 30, 2025.
A total of 9 institutional investors currently hold SPRB stock, with a combined institutional value of approximately $25,135,295 as of the most recent 13F filing period.
Frequently asked questions
SPRB ownershipSpruce Biosciences, Inc. (SPRB) is primarily owned by institutional investors, who hold approximately 100.0% of shares. The largest shareholder is CARLYLE GROUP INC. with a 514.42% stake. Company insiders hold 33.76%. Data sourced from SEC Form 13F as of September 30, 2025.