Companies: 10,795·Total market cap: $144.5T
XORTX Therapeutics Inc.

XORTX Therapeutics Inc.

XRTXNASDAQHealthcare● Active
$2.23
+$0.05(+2.27%)
Market Cap$620863
P/E Ratio
52W High$7.05
52W Low$1.725

XORTX Therapeutics Inc. (XRTX) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · XRTX · as of Sep 30, 2025

Ownership Breakdown

Institutions 36.14%
Insiders 10.22%
Public 53.63%

5

Institutional Holders

▼ 2 vs Q2

$81,474

Total Inst. Value

▲ $19,982 vs Q2

278,489

Shares Outstanding

freeFloat 89.78%

100,658

13F Shares Held

▲ 34,873 vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

XRTX largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 9 holders

HolderShares% OwnedWeightValueReportedChange

CITADEL ADVISORS LLC

pharmaceutical preparations

86.3K1.24%

1.24%

$69.87MNov 14, 2025 47.9K

XTX TOPCO LTD

pharmaceutical preparations

13.8K19.85%

19.85%

$11.19MNov 14, 2025NEW

CLEARSTEAD ADVISORS, LLC

pharmaceutical preparations

2770.40%

0.40%

$225,000Nov 10, 2025— held

UBS GROUP AG

pharmaceutical preparations

2340.34%

0.34%

$190,000Nov 13, 2025 20.6K

SBI SECURITIES CO., LTD.

pharmaceutical preparations

10.00%

0.00%

$1,000Nov 5, 2025NEW

ROYAL BANK OF CANADA

pharmaceutical preparations

00.00%

0.00%

$0Nov 14, 2025EXIT

ADVISOR GROUP HOLDINGS, INC.

pharmaceutical preparations

00.00%

0.00%

$0Nov 14, 2025EXIT

NATIONAL BANK OF CANADA /FI/

pharmaceutical preparations

00.00%

0.00%

$0Nov 14, 2025EXIT

RAYMOND JAMES FINANCIAL INC

pharmaceutical preparations

00.00%

0.00%

$0Nov 14, 2025EXIT

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBearish — more selling than buying

1

Increased

+47.9K shares

2

New Positions

first time holders

1

Decreased

−20.6K shares

4

Sold Out

fully exited

Net shares change (top 50)

+27.3K

+47.9K / −20.6K

Net new holders

-2

2 new / 4 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

XRTX insider trading · insider activity

Source: SEC Form 4

Recent Insider Transactions

Showing 10 most recent · Common Stock only

No recent insider transactions reported.

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

XORTX Therapeutics Inc. (XRTX) is primarily owned by institutional investors, who hold approximately 36.1% of total shares outstanding. Company insiders own approximately 10.22%, while retail and public investors account for the remaining 53.63%.

The largest institutional shareholder of XORTX Therapeutics Inc. is CITADEL ADVISORS LLC, holding approximately 86,326 shares — equal to 1.24% of outstanding shares — as of September 30, 2025.

A total of 5 institutional investors currently hold XRTX stock, with a combined institutional value of approximately $81,474 as of the most recent 13F filing period.

Frequently asked questions

XRTX ownership

XORTX Therapeutics Inc. (XRTX) is primarily owned by institutional investors, who hold approximately 36.1% of shares. The largest shareholder is CITADEL ADVISORS LLC with a 1.24% stake. Company insiders hold 10.22%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns XRTX stockXRTX ownership structureSEC Form 13F institutional holdingsXRTX float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025