Companies: 10,795·Total market cap: $144.5T

Crinetics Pharmaceuticals, Inc.

Crinetics Pharmaceuticals, Inc.

CRNXNASDAQHealthcare● Active

$33.55

+$0.63(+1.91%)

Market Cap$3.5B

P/E Ratio—

52W High$57.99

52W Low$25.83

Avg Volume1.2M

Open$33.09

Beta0.24

Crinetics Pharmaceuticals, Inc. (CRNX) Net Income & Profit History

Annual & trailing net income, net margin, YoY change, and peer profitability context.

CRNX · net income · updated Jun 8, 2026

Core profitability metrics

CRNX · net income · margin · TTM · CAGR

Net income was −$465.3M for FY2025 (fiscal year ending 2025-12-31), down 55.9% year-over-year. Net profit margin was -6046.2%.

FY2025 Net Income−$465.3M▼ -55.9% YoY

Trailing 12M (TTM)−$496.4Mtrailing 4 quarters sum

Net Profit Margin< −999%−$465.3M ÷ $7.7M

YoY Change-55.9%—

5-Year CAGRN/AN/A — contains loss years

FormulaNet Margin = Net Income ÷ Revenue × 100TTM = trailing 4 quarters sumCAGR → N/A if either endpoint ≤ 0

Source: FMP /income-statement · US GAAP · USDUpdated: Jun 8, 2026

Annual net income history

Net Income (bars) · Net Profit Margin % (line)

Net IncomeNet LossNet Margin %

▸ FMP /income-statement · Annual · CRNX net income history · CRNX profit margin

Annual net income data

CRNX · net income history · annual / quarterly

Fiscal YearNet IncomeYoY ChangeNet MarginRevenue

FY2025Loss−$465.3M▼ 55.9%-6046.2%$7.7M

FY2024Loss−$298.4M▼ 39.1%-28720.7%$1.0M

FY2023Loss−$214.5M▼ 30.9%-5345.9%$4.0M

FY2022Loss−$163.9M▼ 52.3%-3460.4%$4.7M

FY2021Loss−$107.6M▼ 45.8%-9985.3%$1.1M

Net income vs peers (Healthcare)

CRNX vs peers · net income

#CompanyNet IncomeYoYNet MarginRelative

#1

Crinetics Pharmaceuticals, Inc.YOU

CRNX

−$465.3M-55.9%-6046.2%

Loss

Johnson & Johnson

$26.80B+90.6%28.5%

Eli Lilly and Company

$20.64B+94.9%31.7%

UnitedHealth Group Incorporated

$12.06B-16.3%2.7%

$4.23B-1.2%6.9%

Healthcare · Sorted by Net Income · FMP /income-statementFull Net Income Rankings →

About Net Income & Methodology

Crinetics Pharmaceuticals, Inc. (CRNX) reported net income of −$465.3M for FY2025 (fiscal year ending 2025-12-31), down 55.9% year-over-year. The net profit margin was -6046.2% — meaning the company kept $-60.46 of every dollar of revenue as profit.

Crinetics Pharmaceuticals, Inc. has not yet achieved annual profitability based on available data (10 fiscal years). The company has reported net losses across all available periods.

Crinetics Pharmaceuticals, Inc.'s net profit margin was -6046.2% for FY2025, based on the latest annual results.

Investors sometimes search for "Crinetics Pharmaceuticals, Inc. net worth" — the company's market capitalization is a separate figure from CRNX net income. Data sourced from FMP /income-statement · US GAAP · USD.

Figures tie to SEC 10-K/10-Q and FMP /income-statement where noted.

Revenue Financial statements Earnings Forecast Price history Market cap Free cash flow

Frequently asked questions

CRNX net income · 4 questions

Crinetics Pharmaceuticals, Inc. is not currently profitable on an annual basis. The company reported a net loss of $465.3M for FY2025.

is CRNX profitabledoes CRNX make a profitCRNX profitabilityCRNX profitable company

▸ Source: FMP /income-statement · GAAP · Crinetics Pharmaceuticals, Inc. · Crinetics Pharmaceuticals, Inc. SEC 10-K & 10-Q filings · US GAAP · Last updated: Jun 8, 2026