Karyopharm Therapeutics Inc.

KPTINASDAQHealthcare● Active

$8.74

+$0.24(+2.82%)

Market Cap$198074122

P/E Ratio—

52W High$10.99

52W Low$3.65

Avg Volume900K

Open$8.68

Beta0.82

Overview

Karyopharm Therapeutics Inc. (KPTI) Number of Employees – History & Annual Headcount

Annual SEC headcount, year-over-year change, and per-employee efficiency — chart and full history below.

SEC EDGAR · FMP · KPTI · as of Feb 13, 2026

Latest filing snapshot

228

-51-18.28%vs prior year

Karyopharm Therapeutics Inc. (KPTI) employee data is sourced from the annual SEC 10-K filing. As of 2025, full-time employees only. Global consolidated headcount. View SEC filing ↗

SEC 10-K·Period end: 2025-12-31·Full-time · Global

Total Employees

228

Change (1Y)

-51

Growth % (1Y)

-18.28%

Revenue / Employee

$640.6K

Net Income / Employee

$-859.8K

Market Cap

$193M

KPTI Employee Count

2013 – 2025 · Annual · SEC filing

Source: SEC annual filings · Hover bar to view year data · Click to view original filing

Employees History

Filing Date	Period End	Employees	Change (1Y)	Growth (1Y)
2026-02-13	2025-12-31	228	-51	-18.28%
2025-02-19	2024-12-31	279	-46	-14.15%
2024-02-29	2023-12-31	325	-60	-15.58%
2023-02-17	2022-12-31	385	-57	-12.90%
2022-03-01	2021-12-31	442	+10	+2.31%
2021-02-24	2020-12-31	432	+85	+24.50%
2020-02-26	2019-12-31	347	+15	+4.52%
2019-02-28	2018-12-31	332	+178	+115.58%
2018-03-15	2017-12-31	154	+46	+42.59%
2017-03-16	2016-12-31	108	+3	+2.86%

▸ Source: SEC Annual Reports (Form 10-K / 20-F). Employee counts as of fiscal year end. Click the ↗ icon at the end of a row to open the original SEC filing in a new tab.

Related Companies — Employee Count

Biotechnology

#SymbolCompanyEmployeesMkt Cap

KPTI

Karyopharm Therapeutics Inc.YOU

Barinthus Biotherapeutics plc

105$29M #4

ALGS

Aligos Therapeutics, Inc.

Medicus Pharma Ltd. Common Stock

12$7M

Source: /stock-peers + /profile.fullTimeEmployees · Click row → /employees · Sorted by headcount · KPTI peer comparison

About KPTI employees

KPTI Employees · Headcount

Karyopharm Therapeutics Inc. (KPTI) employee data is sourced from the annual SEC 10-K filing. As of 2025, Karyopharm Therapeutics Inc. had 228 full-time employees globally. Full-time employees only. Global consolidated headcount.

Karyopharm Therapeutics Inc. employs 228 full-time employees as of the latest filing within the Biotechnology industry. Revenue per employee stands at $640,645, reflecting the company's operational efficiency.

Karyopharm Therapeutics Inc.'s workforce decreased by 51 (18.28%) in 2025 compared to the prior fiscal year. The historical trend reflects the company's expansion and contraction cycles.

Karyopharm Therapeutics Inc.'s revenue per employee of $640,645 positions it among the notable performers in the Biotechnology sector for operational efficiency.

Revenue Financial statements Net income SEC filings Price history Forecast & ratings Ownership Earnings

Frequently Asked Questions

KPTI Employees · 5 questions

As of the latest SEC 10-K filing (2025), Karyopharm Therapeutics Inc. had 228 full-time employees globally. This figure is sourced from the company's mandatory annual disclosure to the SEC.

Karyopharm Therapeutics Inc. employee counthow many employees does Karyopharm Therapeutics Inc. haveKPTI total employees 2025

▸ Data source: FMP /historical-employee-count · SEC EDGAR annual filings · As reported · Global consolidated headcount · As of 2026-02-13