Lexicon Pharmaceuticals, Inc.

LXRXNASDAQHealthcare● Active

$1.88

$-0.03(-1.57%)

Market Cap$835088480

P/E Ratio—

52W High$2.53

52W Low$0.64

Avg Volume2.6M

Open$1.93

Beta1.07

Overview

Lexicon Pharmaceuticals, Inc. (LXRX) Net Income & Profit History

Annual & trailing net income, net margin, YoY change, and peer profitability context.

LXRX · net income · updated Jun 10, 2026

Core profitability metrics

LXRX · net income · margin · TTM · CAGR

Net income was −$50.3M for FY2025 (fiscal year ending 2025-12-31), up 74.9% year-over-year. Net profit margin was -101.1%. Based on available data, Lexicon Pharmaceuticals, Inc. has been profitable since at least 2019.

FY2025 Net Income−$50.3M▲ +74.9% YoY

Trailing 12M (TTM)—trailing 4 quarters sum

Net Profit Margin-101.1%−$50.3M ÷ $49.8M

YoY Change+74.9%—

5-Year CAGRN/AN/A — contains loss years

FormulaNet Margin = Net Income ÷ Revenue × 100TTM = trailing 4 quarters sumCAGR → N/A if either endpoint ≤ 0

Source: FMP /income-statement · US GAAP · USDUpdated: Jun 10, 2026

Annual net income history

Net Income (bars) · Net Profit Margin % (line)

Net IncomeNet LossNet Margin %★ First Profit: 2019

▸ FMP /income-statement · Annual · LXRX net income history · LXRX profit margin

Annual net income data

LXRX · net income history · annual / quarterly

Fiscal YearNet IncomeYoY ChangeNet MarginRevenue

FY2025Loss−$50.3M▲ +74.9%-101.1%$49.8M

FY2024Loss−$200.4M▼ 13.1%-644.8%$31.1M

FY2023Loss−$177.1M▼ 73.7%-14710.9%$1.2M

FY2022Loss−$101.9M▼ 16.2%-73341.0%$139,000

FY2021Loss−$87.8M▼ 49.8%-29449.0%$298,000

Net income vs peers (Healthcare)

LXRX vs peers · net income

#CompanyNet IncomeYoYNet MarginRelative

Eli Lilly and Company

LLY

$20.64B+94.9%31.7%

77%

UnitedHealth Group Incorporated

Healthcare · Sorted by Net Income · FMP /income-statementFull Net Income Rankings →

About Net Income & Methodology

Lexicon Pharmaceuticals, Inc. (LXRX) reported net income of −$50.3M for FY2025 (fiscal year ending 2025-12-31), up 74.9% year-over-year. The net profit margin was -101.1% — meaning the company kept $-1.01 of every dollar of revenue as profit.

Based on available data, Lexicon Pharmaceuticals, Inc. has been profitable since at least 2019. Net income reached a peak of $130.1M in FY2019. Data available for 15 fiscal years.

Lexicon Pharmaceuticals, Inc.'s net profit margin was -101.1% for FY2025, based on the latest annual results.

Investors sometimes search for "Lexicon Pharmaceuticals, Inc. net worth" — the company's market capitalization is a separate figure from LXRX net income. Data sourced from FMP /income-statement · US GAAP · USD.

Figures tie to SEC 10-K/10-Q and FMP /income-statement where noted.

Revenue Financial statements Earnings Forecast Price history Market cap Free cash flow

Frequently asked questions

LXRX net income · 4 questions

Lexicon Pharmaceuticals, Inc. is not currently profitable on an annual basis. The company reported a net loss of $50.3M for FY2025.

is LXRX profitabledoes LXRX make a profitLXRX profitabilityLXRX profitable company

▸ Source: FMP /income-statement · GAAP · Lexicon Pharmaceuticals, Inc. · Lexicon Pharmaceuticals, Inc. SEC 10-K & 10-Q filings · US GAAP · Last updated: Jun 10, 2026