Companies: 10,795·Total market cap: $144.5T
Septerna, Inc.

Septerna, Inc.

SEPNNASDAQHealthcare● Active
$31.01
+$0.60(+1.98%)
Market Cap$1.4B
P/E Ratio
52W High$32.63
52W Low$9.852
Overview

Septerna, Inc. (SEPN) Insider Trading

Form 4 buy vs sell counts, ratio, and sentiment — switch this quarter or last 12 months; chart and transactions below.

SEC EDGAR · FMP · SEPN · as of Jun 9, 2026

Activity summary

Buy transactions

0

P-Purchase only

Sell transactions

9

12 Months

Buy/Sell ratio

0.00

Buy/Sell (by trades)

Overall sentiment

BEARISH
↑ Buy 0%Active transactions only · RSU vesting excluded100% Sell ↓

Septerna, Inc. insiders have been primarily selling shares over the past 12 Months. Selling activity is often driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment toward the company.

Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · Buy = P-Purchase only · Sell = S-Sale only

As of Jun 9, 2026

SEPN insider buying and selling by quarter

SEPN insider selling · SEPN insider buying stocks · quarterly insider activity

Total insider buying (incl. awards)Total insider selling
1.3M642K0
2025 Q3
2025 Q4
2026 Q1
2026 Q2

Mobile shows last 4Q · Desktop shows full 8Q

Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · last 8 quarters

As of Jun 9, 2026

Active insiders

Most active in past 12 months · SEPN ceo insider trading

Showing all insiders · Click a card to filter the transactions table below

Aggregated from reportingName · top 5 by trade count (12M) · no extra API

Recent insider transactions

SEPN executive sell shares · SEPN board member insider trading · SEPN insider trading SEC filing

Showing 26 most recent · Common Stock · Form 4 only

Scroll horizontally to see all columns

Shaikhly Samira

CPO

Option

Date

Jun 1

Shares

637

Price

$2.76

Value

$2K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Option

Date

Jun 1

Shares

943

Price

$2.76

Value

$3K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Option

Date

Jun 1

Shares

4,355

Price

$1.55

Value

$7K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Sale

Date

Jun 1

Shares

1,700

Price

$27.78

Value

$47K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Sale

Date

Jun 1

Shares

1,346

Price

$28.79

Value

$39K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Sale

Date

Jun 1

Shares

2,889

Price

$29.66

Value

$86K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Option

Date

May 26

Shares

11,798

Price

$6.81

Value

$80K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Sale

Date

May 26

Shares

11,798

Price

$30.06

Value

$355K

View Form 4 on SEC.gov

Bhatt Elizabeth

President and COO

Option

Date

Apr 15

Shares

4,000

Price

$6.81

Value

$27K

View Form 4 on SEC.gov

Bhatt Elizabeth

President and COO

Sale

Date

Apr 15

Shares

2,573

Price

$23.76

Value

$61K

View Form 4 on SEC.gov

Bhatt Elizabeth

President and COO

Sale

Date

Apr 15

Shares

1,101

Price

$25.24

Value

$28K

View Form 4 on SEC.gov

Bhatt Elizabeth

President and COO

Sale

Date

Apr 15

Shares

326

Price

$25.86

Value

$8K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Option

Date

Mar 2

Shares

5,101

Price

$2.76

Value

$14K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Sale

Date

Mar 2

Shares

4,090

Price

$27.51

Value

$112K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Option

Date

Mar 2

Shares

11,638

Price

$2.76

Value

$32K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Option

Date

Mar 2

Shares

53,714

Price

$1.55

Value

$83K

View Form 4 on SEC.gov

Shaikhly Samira

CPO

Sale

Date

Mar 2

Shares

66,363

Price

$28.14

Value

$1.87M ⚡

View Form 4 on SEC.gov

Bhatt Elizabeth

President and COO

Option

Date

Feb 18

Shares

4,000

Price

$6.81

Value

$27K

View Form 4 on SEC.gov

Bhatt Elizabeth

President and COO

Sale

Date

Feb 18

Shares

2,200

Price

$28.46

Value

$63K

View Form 4 on SEC.gov

Bhatt Elizabeth

President and COO

Sale

Date

Feb 18

Shares

1,800

Price

$29.58

Value

$53K

View Form 4 on SEC.gov

Long Daniel D.

SVP, Drug Discovery

Sale

Date

Nov 10

Shares

3,501

Price

$18.06

Value

$63K

View Form 4 on SEC.gov

Klein Uwe

SVP, Biological Sciences

Option

Date

Aug 18

Shares

7,621

Price

$6.81

Value

$52K

View Form 4 on SEC.gov

Klein Uwe

SVP, Biological Sciences

Option

Date

Aug 18

Shares

4,935

Price

$2.76

Value

$14K

View Form 4 on SEC.gov

Klein Uwe

SVP, Biological Sciences

Option

Date

Aug 18

Shares

10,452

Price

$2.76

Value

$29K

View Form 4 on SEC.gov

Finer Jeffrey

CEO and President · Director

Option

Date

Apr 3

Shares

5,000

Price

$2.76

Value

$14K

View Form 4 on SEC.gov

⚡ = value ≥ $1M · Award/Option price shows — · formType=4 · securityName=Common Stock · url → sec.gov/Archives/edgar

1 / 2

Source: SEC EDGAR · Form 4 filings · ⚡ = value ≥ $1M · Award/Option price shows —

About SEPN insider trading

SEPN insider trades

Septerna, Inc. (SEPN) insider trading data is sourced from SEC Form 4 filings submitted by corporate insiders, including Shaikhly Samira (CPO), Bhatt Elizabeth (President and COO), Klein Uwe (SVP, Biological Sciences). Over the past 12 months, 4 insiders have filed transactions with the SEC. SEPN insiders have been primarily selling, which may reflect pre-scheduled Rule 10b5-1 plan executions.

For Septerna, Inc.'s institutional ownership breakdown and insider ownership percentage, see the Ownership tab → Ownership tab →

Buy/Sell signal logic
acquisitionOrDisposition field:
A = Acquisition (buy) · D = Disposition (sell)
RSU vesting (M-Exempt) excluded from sentiment
Form 4SEC filing required within 2 business days of any insider transaction
10b5-1Pre-scheduled trading plan that allows insiders to sell on autopilot
Open MktDirect purchase or sale on the open market (excludes awards, options)

Frequently asked questions

SEPN insider trading · 5 questions

The insiders of Septerna, Inc. (SEPN) include executives and directors such as Shaikhly Samira (CPO), Bhatt Elizabeth (President and COO), Klein Uwe (SVP, Biological Sciences), among others. Over the past 12 months, 4 insiders have filed Form 4 transactions with the SEC. Insider transactions are required to be reported within 2 business days of the trade date.

SEPN board member insider tradingwho are SEPN insidersSEPN insider rosterSepterna, Inc. executives insider activity

Source: FMP /stable/insider-trading/search · SEC EDGAR Form 3 & 4 · acquisitionOrDisposition A=Buy, D=Sell · RSU vesting (M-Exempt) excluded from sentiment bar · As of Jun 9, 2026