Spruce Biosciences, Inc.

SPRBNASDAQHealthcare● Active

$49.32

$-1.11(-2.20%)

Market Cap$67668470

P/E Ratio—

52W High$838.125

52W Low$7

Avg Volume63K

Open$50.40

Beta3.16

Overview

Spruce Biosciences, Inc. (SPRB) Insider Trading

Form 4 buy vs sell counts, ratio, and sentiment — switch this quarter or last 12 months; chart and transactions below.

SEC EDGAR · FMP · SPRB · as of Jun 9, 2026

Activity summary

Buy transactions

P-Purchase only

Sell transactions

12 Months

Buy/Sell ratio

0.50

Buy/Sell (by trades)

Overall sentiment

BEARISH

↑ Buy 33%Active transactions only · RSU vesting excluded67% Sell ↓

Spruce Biosciences, Inc. insiders have been primarily selling shares over the past 12 Months. Selling activity is often driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment toward the company.

▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · Buy = P-Purchase only · Sell = S-Sale only

As of Jun 9, 2026

SPRB insider buying and selling by quarter

SPRB insider selling · SPRB insider buying stocks · quarterly insider activity

Total insider buying (incl. awards)Total insider selling

4.2M2.1M0

2023 Q2

2023 Q4

2024 Q1

2024 Q2

2024 Q4

2025 Q3

2025 Q4

2026 Q1

Mobile shows last 4Q · Desktop shows full 8Q

▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · last 8 quarters

As of Jun 9, 2026

Active insiders

Most active in past 12 months · SPRB ceo insider trading

Showing all insiders · Click a card to filter the transactions table below

▸ Aggregated from reportingName · top 5 by trade count (12M) · no extra API

Recent insider transactions

SPRB executive sell shares · SPRB board member insider trading · SPRB insider trading SEC filing

Showing 22 most recent · Common Stock · Form 4 only

Scroll horizontally to see all columns

Date	Insider	Type	Shares	Price	Value	After trans.	Filing
Dec 11, 2025	Ways Douglas Kirk Interim Chief Medical Officer · Director	Option	1,250	—	—	1,250	Form 4
Dec 31, 2025	Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER · Director	Award	4,690	$4.53	$21K	19,004	Form 4
Dec 15, 2025	Gharib Samir M. PRESIDENT AND CFO	Option	513	—	—	8,447	Form 4
Dec 15, 2025	Gharib Samir M. PRESIDENT AND CFO	Other	184	$80.67	$15K	8,263	Form 4
Dec 15, 2025	Gharib Samir M. PRESIDENT AND CFO	Option	496	—	—	8,112	Form 4
Dec 15, 2025	Gharib Samir M. PRESIDENT AND CFO	Other	178	$80.67	$14K	7,934	Form 4
Dec 15, 2025	Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER · Director	Option	1,196	—	—	14,922	Form 4
Dec 15, 2025	Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER · Director	Option	1,480	—	—	14,478	Form 4
Dec 15, 2025	Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER · Director	Other	608	$80.67	$49K	14,314	Form 4
Dec 15, 2025	Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER · Director	Other	752	$80.67	$61K	13,726	Form 4
Dec 11, 2025	Gharib Samir M. PRESIDENT AND CFO	Option	1,900	—	—	8,296	Form 4
Dec 11, 2025	Gharib Samir M. PRESIDENT AND CFO	Other	680	$88.41	$60K	7,616	Form 4
Dec 10, 2025	Gharib Samir M. PRESIDENT AND CFO	Option	514	—	—	6,580	Form 4
Dec 10, 2025	Gharib Samir M. PRESIDENT AND CFO	Other	184	$85.67	$16K	6,396	Form 4
Dec 11, 2025	Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER · Director	Option	4,950	—	—	15,192	Form 4
Dec 11, 2025	Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER · Director	Other	2,194	$88.41	$194K	12,998	Form 4
Dec 10, 2025	Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER · Director	Option	1,196	—	—	10,670	Form 4
Dec 10, 2025	Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER · Director	Other	428	$85.67	$37K	10,242	Form 4
Oct 20, 2025	Gharib Samir M. PRESIDENT AND CFO	Option	2,053	—	—	6,727	Form 4
Oct 20, 2025	Gharib Samir M. PRESIDENT AND CFO	Other	661	$148.16	$98K	6,066	Form 4
Oct 20, 2025	Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER · Director	Option	4,784	—	—	11,013	Form 4
Oct 20, 2025	Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER · Director	Other	1,539	$148.16	$228K	9,474	Form 4

Ways Douglas Kirk

Interim Chief Medical Officer · Director

Option

Date

Dec 11

1,250

Price

—

Value

—

View Form 4 on SEC.gov

Szwarcberg Javier B.

CHIEF EXECUTIVE OFFICER · Director

Award

Date

Dec 31

4,690

Price

$4.53

Value

$21K

View Form 4 on SEC.gov

Gharib Samir M.

PRESIDENT AND CFO

Option

Date

Dec 15

513

Price

—

Value

—

View Form 4 on SEC.gov

Gharib Samir M.

PRESIDENT AND CFO

Other

Date

Dec 15

184

Price

$80.67

Value

$15K

View Form 4 on SEC.gov

Gharib Samir M.

PRESIDENT AND CFO

Option

Date

Dec 15

496

Price

—

Value

—

View Form 4 on SEC.gov

Gharib Samir M.

PRESIDENT AND CFO

Other

Date

Dec 15

178

Price

$80.67

Value

$14K

View Form 4 on SEC.gov

Szwarcberg Javier B.

CHIEF EXECUTIVE OFFICER · Director

Option

Date

Dec 15

1,196

Price

—

Value

—

View Form 4 on SEC.gov

Szwarcberg Javier B.

CHIEF EXECUTIVE OFFICER · Director

Option

Date

Dec 15

1,480

Price

—

Value

—

View Form 4 on SEC.gov

Szwarcberg Javier B.

CHIEF EXECUTIVE OFFICER · Director

Other

Date

Dec 15

608

Price

$80.67

Value

$49K

View Form 4 on SEC.gov

Szwarcberg Javier B.

CHIEF EXECUTIVE OFFICER · Director

Other

Date

Dec 15

752

Price

$80.67

Value

$61K

View Form 4 on SEC.gov

Gharib Samir M.

PRESIDENT AND CFO

Option

Date

Dec 11

1,900

Price

—

Value

—

View Form 4 on SEC.gov

Gharib Samir M.

PRESIDENT AND CFO

Other

Date

Dec 11

680

Price

$88.41

Value

$60K

View Form 4 on SEC.gov

Gharib Samir M.

PRESIDENT AND CFO

Option

Date

Dec 10

514

Price

—

Value

—

View Form 4 on SEC.gov

Gharib Samir M.

PRESIDENT AND CFO

Other

Date

Dec 10

184

Price

$85.67

Value

$16K

View Form 4 on SEC.gov

Szwarcberg Javier B.

CHIEF EXECUTIVE OFFICER · Director

Option

Date

Dec 11

4,950

Price

—

Value

—

View Form 4 on SEC.gov

Szwarcberg Javier B.

CHIEF EXECUTIVE OFFICER · Director

Other

Date

Dec 11

2,194

Price

$88.41

Value

$194K

View Form 4 on SEC.gov

Szwarcberg Javier B.

CHIEF EXECUTIVE OFFICER · Director

Option

Date

Dec 10

1,196

Price

—

Value

—

View Form 4 on SEC.gov

Szwarcberg Javier B.

CHIEF EXECUTIVE OFFICER · Director

Other

Date

Dec 10

428

Price

$85.67

Value

$37K

View Form 4 on SEC.gov

Gharib Samir M.

PRESIDENT AND CFO

Option

Date

Oct 20

2,053

Price

—

Value

—

View Form 4 on SEC.gov

Gharib Samir M.

PRESIDENT AND CFO

Other

Date

Oct 20

661

Price

$148.16

Value

$98K

View Form 4 on SEC.gov

Szwarcberg Javier B.

CHIEF EXECUTIVE OFFICER · Director

Option

Date

Oct 20

4,784

Price

—

Value

—

View Form 4 on SEC.gov

Szwarcberg Javier B.

CHIEF EXECUTIVE OFFICER · Director

Other

Date

Oct 20

1,539

Price

$148.16

Value

$228K

View Form 4 on SEC.gov

▸ Source: SEC EDGAR · Form 4 filings · ⚡ = value ≥ $1M · Award/Option price shows —

About SPRB insider trading

SPRB insider trades

Spruce Biosciences, Inc. (SPRB) insider trading data is sourced from SEC Form 4 filings submitted by corporate insiders, including Szwarcberg Javier B. (CHIEF EXECUTIVE OFFICER · Director), Gharib Samir M. (PRESIDENT AND CFO), Ways Douglas Kirk (Interim Chief Medical Officer · Director). Over the past 12 months, 3 insiders have filed transactions with the SEC. SPRB insiders have been primarily selling, which may reflect pre-scheduled Rule 10b5-1 plan executions.

For Spruce Biosciences, Inc.'s institutional ownership breakdown and insider ownership percentage, see the Ownership tab → Ownership tab →

Buy/Sell signal logic

acquisitionOrDisposition field:

A = Acquisition (buy) · D = Disposition (sell)

RSU vesting (M-Exempt) excluded from sentiment

Form 4SEC filing required within 2 business days of any insider transaction

10b5-1Pre-scheduled trading plan that allows insiders to sell on autopilot

Open MktDirect purchase or sale on the open market (excludes awards, options)

Ownership SEC filings Financial statements Price history Forecast & ratings Earnings

Frequently asked questions

SPRB insider trading · 5 questions

The insiders of Spruce Biosciences, Inc. (SPRB) include executives and directors such as Szwarcberg Javier B. (CHIEF EXECUTIVE OFFICER · Director), Gharib Samir M. (PRESIDENT AND CFO), Ways Douglas Kirk (Interim Chief Medical Officer · Director), among others. Over the past 12 months, 3 insiders have filed Form 4 transactions with the SEC. Insider transactions are required to be reported within 2 business days of the trade date.

SPRB board member insider tradingwho are SPRB insidersSPRB insider rosterSpruce Biosciences, Inc. executives insider activity

▸ Source: FMP /stable/insider-trading/search · SEC EDGAR Form 3 & 4 · acquisitionOrDisposition A=Buy, D=Sell · RSU vesting (M-Exempt) excluded from sentiment bar · As of Jun 9, 2026