Spero Therapeutics, Inc.
Spero Therapeutics, Inc. (SPRO) Insider Trading
Form 4 buy vs sell counts, ratio, and sentiment — switch this quarter or last 12 months; chart and transactions below.
SEC EDGAR · FMP · SPRO · as of Jun 9, 2026
Activity summary
Buy transactions
0
P-Purchase only
Sell transactions
7
12 Months
Buy/Sell ratio
0.00
Buy/Sell (by trades)
Overall sentiment
Spero Therapeutics, Inc. insiders have been primarily selling shares over the past 12 Months. Selling activity is often driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment toward the company.
▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · Buy = P-Purchase only · Sell = S-Sale only
As of Jun 9, 2026
SPRO insider buying and selling by quarter
SPRO insider selling · SPRO insider buying stocks · quarterly insider activity
Mobile shows last 4Q · Desktop shows full 8Q
▸ Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · last 8 quarters
As of Jun 9, 2026
Active insiders
Most active in past 12 months · SPRO ceo insider trading
Showing all insiders · Click a card to filter the transactions table below
▸ Aggregated from reportingName · top 5 by trade count (12M) · no extra API
Recent insider transactions
SPRO executive sell shares · SPRO board member insider trading · SPRO insider trading SEC filing
Scroll horizontally to see all columns
| Date | Insider | Type | Shares | Value | Filing |
|---|---|---|---|---|---|
| May 4, 2026 | Rajavelu Esther See Remarks | Sale | 25,240 | $63K | Form 4 |
| Feb 6, 2026 | Rajavelu Esther See Remarks | Sale | 37,101 | $88K | Form 4 |
| Feb 6, 2026 | Rajavelu Esther See Remarks | Sale | 50,816 | $120K | Form 4 |
| Feb 6, 2026 | Keutzer Timothy COO | Sale | 18,652 | $44K | Form 4 |
| Feb 2, 2026 | Keutzer Timothy COO | Award | 68,000 | — | Form 4 |
| Feb 2, 2026 | Keutzer Timothy COO | Sale | 18,891 | $42K | Form 4 |
| Feb 3, 2026 | Keutzer Timothy COO | Sale | 24,224 | $52K | Form 4 |
| Feb 4, 2026 | Keutzer Timothy COO | Sale | 3,471 | $8K | Form 4 |
| Feb 2, 2026 | Rajavelu Esther See Remarks | Award | 249,000 | — | Form 4 |
| Feb 2, 2026 | Rajavelu Esther See Remarks | Sale | 18,442 | $41K | Form 4 |
| Nov 7, 2025 | Rajavelu Esther See Remarks | Sale | 40,270 | $95K | Form 4 |
| Aug 28, 2025 | Mahadevia Ankit Director | Sale | 6,572 | $13K | Form 4 |
| Aug 28, 2025 | Keutzer Timothy COO | Sale | 1,695 | $3K | Form 4 |
| Jun 12, 2025 | Mahadevia Ankit Director | Award | 20,000 | — | Form 4 |
| Jun 12, 2025 | Deshpande Milind Director | Award | 20,000 | — | Form 4 |
| Jun 12, 2025 | Jackson Scott Thomas Director | Award | 20,000 | — | Form 4 |
| Jun 12, 2025 | VINK PATRICK V.J.J. Director | Award | 20,000 | — | Form 4 |
| Jun 12, 2025 | Pottage John C Jr Director | Award | 20,000 | — | Form 4 |
| Jun 12, 2025 | Smith Cynthia Director | Award | 20,000 | — | Form 4 |
| Jun 12, 2025 | THOMAS FRANK E Director | Award | 20,000 | — | Form 4 |
| Jun 12, 2025 | Tregoning Kathleen Director | Award | 20,000 | — | Form 4 |
| May 2, 2025 | Rajavelu Esther See Remarks | Award | 185,000 | — | Form 4 |
| Feb 3, 2025 | Keutzer Timothy COO | Award | 266,139 | — | Form 4 |
| Feb 5, 2025 | Keutzer Timothy COO | Sale | 3,974 | $3K | Form 4 |
| Feb 5, 2025 | Keutzer Timothy COO | Sale | 27,643 | $22K | Form 4 |
⚡ = value ≥ $1M · Award/Option price shows — · formType=4 · securityName=Common Stock · url → sec.gov/Archives/edgar
▸ Source: SEC EDGAR · Form 4 filings · ⚡ = value ≥ $1M · Award/Option price shows —
About SPRO insider trading
SPRO insider trades
Spero Therapeutics, Inc. (SPRO) insider trading data is sourced from SEC Form 4 filings submitted by corporate insiders, including Rajavelu Esther (See Remarks), Keutzer Timothy (COO), Mahadevia Ankit (Director). Over the past 12 months, 5 insiders have filed transactions with the SEC. SPRO insiders have been primarily selling, which may reflect pre-scheduled Rule 10b5-1 plan executions.
For Spero Therapeutics, Inc.'s institutional ownership breakdown and insider ownership percentage, see the Ownership tab → Ownership tab →
Frequently asked questions
SPRO insider trading · 5 questionsThe insiders of Spero Therapeutics, Inc. (SPRO) include executives and directors such as Rajavelu Esther (See Remarks), Keutzer Timothy (COO), Mahadevia Ankit (Director), among others. Over the past 12 months, 5 insiders have filed Form 4 transactions with the SEC. Insider transactions are required to be reported within 2 business days of the trade date.
▸ Source: FMP /stable/insider-trading/search · SEC EDGAR Form 3 & 4 · acquisitionOrDisposition A=Buy, D=Sell · RSU vesting (M-Exempt) excluded from sentiment bar · As of Jun 9, 2026