Companies: 10,795·Total market cap: $144.5T
Alpine Immune Sciences, Inc.

Alpine Immune Sciences, Inc.

ALPNNASDAQHealthcare
$64.97
+$0.01(+0.02%)
Market Cap$4.5B
P/E Ratio
52W High$65.0
52W Low$8.33

Alpine Immune Sciences, Inc. (ALPN) Insider Trading

Form 4 buy vs sell counts, ratio, and sentiment — switch this quarter or last 12 months; chart and transactions below.

SEC EDGAR · FMP · ALPN · as of Jun 8, 2026

Activity summary

Buy transactions

2

P-Purchase only

Sell transactions

33

12 Months

Buy/Sell ratio

0.06

Buy/Sell (by trades)

Overall sentiment

BEARISH
↑ Buy 6%Active transactions only · RSU vesting excluded94% Sell ↓

Alpine Immune Sciences, Inc. insiders have been primarily selling shares over the past 12 Months. Selling activity is often driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment toward the company.

Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · Buy = P-Purchase only · Sell = S-Sale only

As of Jun 8, 2026

ALPN insider buying and selling by quarter

ALPN insider selling · ALPN insider buying stocks · quarterly insider activity

Total insider buying (incl. awards)Total insider selling
14.7M7.3M0
2023 Q2
2023 Q4
2024 Q1
2024 Q2

Mobile shows last 4Q · Desktop shows full 8Q

Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · last 8 quarters

As of Jun 8, 2026

Recent insider transactions

ALPN executive sell shares · ALPN board member insider trading · ALPN insider trading SEC filing

Showing 20 most recent · Common Stock · Form 4 only

Scroll horizontally to see all columns

Peetz Christopher

Director

Other

Date

May 20

Shares

1,900

Price

$65.00

Value

$124K

View Form 4 on SEC.gov

CONWAY ROBERT E

Director

Other

Date

May 20

Shares

50,000

Price

$65.00

Value

$3.25M ⚡

View Form 4 on SEC.gov

Topper James N

Director

Other

Date

May 18

Shares

2,829,347

Price

$65.00

Value

$183.91M ⚡

View Form 4 on SEC.gov

Thompson Peter A.

Director

Other

Date

May 18

Shares

264,315

Price

$65.00

Value

$17.18M ⚡

View Form 4 on SEC.gov

Cui Xiangmin

Director

Other

Date

May 18

Shares

1,735,544

Price

$65.00

Value

$112.81M ⚡

View Form 4 on SEC.gov

Rickey James Paul

See Remarks

Other

Date

May 20

Shares

26,761

Price

$65.00

Value

$1.74M ⚡

View Form 4 on SEC.gov

Rickey James Paul

See Remarks

Other

Date

May 20

Shares

31,200

Price

$65.00

Value

$2.03M ⚡

View Form 4 on SEC.gov

PENG STANFORD L

See Remarks

Other

Date

May 20

Shares

296,163

Price

$65.00

Value

$19.25M ⚡

View Form 4 on SEC.gov

PENG STANFORD L

See Remarks

Other

Date

May 20

Shares

48,000

Price

$65.00

Value

$3.12M ⚡

View Form 4 on SEC.gov

GOLD MITCHELL

Executive Chairman and CEO · Director

Other

Date

May 20

Shares

13,245

Price

$65.00

Value

$861K

View Form 4 on SEC.gov

GOLD MITCHELL

Executive Chairman and CEO · Director

Other

Date

May 18

Shares

2,627,157

Price

$65.00

Value

$170.77M ⚡

View Form 4 on SEC.gov

GOLD MITCHELL

Executive Chairman and CEO · Director

Other

Date

May 20

Shares

96,000

Price

$65.00

Value

$6.24M ⚡

View Form 4 on SEC.gov

FUHS ULRICH MARTIN

CAO

Other

Date

May 20

Shares

22,820

Price

$65.00

Value

$1.48M ⚡

View Form 4 on SEC.gov

FUHS ULRICH MARTIN

CAO

Other

Date

May 20

Shares

7,300

Price

$65.00

Value

$475K

View Form 4 on SEC.gov

DURAND REMY

Chief Business Officer

Other

Date

May 20

Shares

102,192

Price

$65.00

Value

$6.64M ⚡

View Form 4 on SEC.gov

DURAND REMY

Chief Business Officer

Other

Date

May 20

Shares

31,200

Price

$65.00

Value

$2.03M ⚡

View Form 4 on SEC.gov

ORBIMED ADVISORS LLC

Director

Other

Date

May 18

Shares

264,315

Price

$65.00

Value

$17.18M ⚡

View Form 4 on SEC.gov

PENG STANFORD L

See Remarks

Option

Date

May 8

Shares

13,377

Price

$6.33

Value

$85K

View Form 4 on SEC.gov

PENG STANFORD L

See Remarks

Option

Date

May 8

Shares

26,912

Price

$3.23

Value

$87K

View Form 4 on SEC.gov

PENG STANFORD L

See Remarks

Option

Date

May 8

Shares

22,593

Price

$11.31

Value

$256K

View Form 4 on SEC.gov

Source: SEC EDGAR · Form 4 filings · ⚡ = value ≥ $1M · Award/Option price shows —

About ALPN insider trading

ALPN insider trades

Alpine Immune Sciences, Inc. (ALPN) insider trading data is sourced from SEC Form 4 filings submitted by corporate insiders, including ALPN. Over the past 12 months, 0 insiders have filed transactions with the SEC. ALPN insiders have been primarily selling, which may reflect pre-scheduled Rule 10b5-1 plan executions.

For Alpine Immune Sciences, Inc.'s institutional ownership breakdown and insider ownership percentage, see the Ownership tab → Ownership tab →

Buy/Sell signal logic
acquisitionOrDisposition field:
A = Acquisition (buy) · D = Disposition (sell)
RSU vesting (M-Exempt) excluded from sentiment
Form 4SEC filing required within 2 business days of any insider transaction
10b5-1Pre-scheduled trading plan that allows insiders to sell on autopilot
Open MktDirect purchase or sale on the open market (excludes awards, options)

Frequently asked questions

ALPN insider trading · 5 questions

The insiders of Alpine Immune Sciences, Inc. (ALPN) include executives and directors such as ALPN, among others. Over the past 12 months, 0 insiders have filed Form 4 transactions with the SEC. Insider transactions are required to be reported within 2 business days of the trade date.

ALPN board member insider tradingwho are ALPN insidersALPN insider rosterAlpine Immune Sciences, Inc. executives insider activity

Source: FMP /stable/insider-trading/search · SEC EDGAR Form 3 & 4 · acquisitionOrDisposition A=Buy, D=Sell · RSU vesting (M-Exempt) excluded from sentiment bar · As of Jun 8, 2026