Companies: 10,795·Total market cap: $144.5T
Ampio Pharmaceuticals, Inc.

Ampio Pharmaceuticals, Inc.

AMPEOTCHealthcare● Active
$0.18
+$0.00(+0.00%)
Market Cap$207884
P/E Ratio
52W High$0.6435
52W Low$0.0001

Ampio Pharmaceuticals, Inc. (AMPE) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · AMPE · as of Sep 30, 2025

Ownership Breakdown

Institutions 0.04%
Insiders 1.53%
Public 98.43%

1

Institutional Holders

$1

Total Inst. Value

1.14M

Shares Outstanding

freeFloat 98.47%

440

13F Shares Held

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

AMPE largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 1 holders

HolderShares% OwnedWeightValueReportedChange

CYPRESS CAPITAL MANAGEMENT LLC (WY)

pharmaceutical preparations

4405.33%

5.33%

$1,000Nov 3, 2025— held

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

0

Increased

+0 shares

0

New Positions

first time holders

0

Decreased

−0 shares

0

Sold Out

fully exited

Net shares change (top 50)

+0

+0 / −0

Net new holders

+0

0 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

AMPE insider trading · insider activity

Source: SEC Form 4

Buy 100%Active transactions only0% Sell

Insiders have been net buyers of shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

8

Buy transactions

0

Sell transactions

0.00

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

BUCHI J KEVIN

director

Jun 9, 2023Purchase21,858$0.29$6.3K146.9KForm 4 ↗

BUCHI J KEVIN

director

Jun 8, 2023Purchase25,000$0.30$7.4K125.0KForm 4 ↗

MARTINO MICHAEL A

CEO

May 24, 2023Purchase76,890$0.29$22.1K76.9KForm 4 ↗

BUCHI J KEVIN

director

May 16, 2023Purchase32,534$0.27$8.9K100.0KForm 4 ↗

BUCHI J KEVIN

director

May 15, 2023Purchase44,026$0.25$10.9K67.5KForm 4 ↗

BUCHI J KEVIN

director

May 12, 2023Purchase23,440$0.24$5.5K23.4KForm 4 ↗

Stevens David R

director

May 12, 2023Purchase45,000$0.22$9.9K104.0KForm 4 ↗

Stevens David R

director

May 11, 2023Purchase25,000$0.21$5.4K59.0KForm 4 ↗

Stevens David R

director

May 11, 2023Purchase25,000$0.22$5.5K34.0KForm 4 ↗

JOBES ELIZABETH VARKI

director

Mar 1, 2022Award150,000$0.45$67.7K150.0KForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Ampio Pharmaceuticals, Inc. (AMPE) is primarily owned by institutional investors, who hold approximately 0.0% of total shares outstanding. Company insiders own approximately 1.53%, while retail and public investors account for the remaining 98.43%.

The largest institutional shareholder of Ampio Pharmaceuticals, Inc. is CYPRESS CAPITAL MANAGEMENT LLC (WY), holding approximately 440 shares — equal to 5.33% of outstanding shares — as of September 30, 2025.

A total of 1 institutional investors currently hold AMPE stock, with a combined institutional value of approximately $1 as of the most recent 13F filing period.

Frequently asked questions

AMPE ownership

Ampio Pharmaceuticals, Inc. (AMPE) is primarily owned by institutional investors, who hold approximately 0.0% of shares. The largest shareholder is CYPRESS CAPITAL MANAGEMENT LLC (WY) with a 5.33% stake. Company insiders hold 1.53%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns AMPE stockAMPE ownership structureSEC Form 13F institutional holdingsAMPE float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025