Companies: 10,795·Total market cap: $144.5T
AnaptysBio, Inc.

AnaptysBio, Inc.

ANABNASDAQHealthcare● Active
$51.36
+$0.99(+1.97%)
Market Cap$2.2B
P/E Ratio
52W High$72.36
52W Low$11.404

AnaptysBio, Inc. (ANAB) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · ANAB · as of Sep 30, 2025

Ownership Breakdown

Institutions 73.47%
Insiders 6.56%
Public 19.97%

177

Institutional Holders

▲ 24 vs Q2

$980.50M

Total Inst. Value

▲ $164.09M vs Q2

43.12M

Shares Outstanding

freeFloat 93.44%

31.68M

13F Shares Held

▼ 5.09M vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

ANAB largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

ECOR1 CAPITAL, LLC

pharmaceutical preparations

7.88M27.35%

27.35%

$241.29BNov 14, 2025— held

POINT72 ASSET MANAGEMENT, L.P.

pharmaceutical preparations

2.27M7.86%

7.86%

$69.37BNov 14, 2025 209.3K

BLACKROCK, INC.

pharmaceutical preparations

1.72M5.98%

5.98%

$52.74BNov 12, 2025 64.6K

MORGAN STANLEY

pharmaceutical preparations

1.56M5.40%

5.40%

$47.65BMay 27, 2026 313.6K

MILLENNIUM MANAGEMENT LLC

pharmaceutical preparations

1.52M5.27%

5.27%

$46.52BNov 14, 2025 1.32M

VANGUARD GROUP INC

pharmaceutical preparations

1.48M5.13%

5.13%

$45.23BNov 7, 2025 60.6K

TANG CAPITAL MANAGEMENT LLC

pharmaceutical preparations

1.33M4.63%

4.63%

$40.84BNov 14, 2025 2.8K

FIRST LIGHT ASSET MANAGEMENT, LLC

pharmaceutical preparations

990.2K3.44%

3.44%

$30.32BNov 14, 2025 2.55M

STATE STREET CORP

pharmaceutical preparations

873.4K3.03%

3.03%

$26.74BNov 14, 2025 52.4K

ASSENAGON ASSET MANAGEMENT S.A.

pharmaceutical preparations

839.9K2.92%

2.92%

$25.72BOct 7, 2025 823.0K

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBullish — more buying than selling

24

Increased

+4.14M shares

2

New Positions

first time holders

19

Decreased

−8.28M shares

0

Sold Out

fully exited

Net shares change (top 50)

4.14M

+4.14M / −8.28M

Net new holders

+7

2 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

ANAB insider trading · insider activity

Source: SEC Form 4

35

Buy transactions

33

Sell transactions

1.06

Buy/Sell ratio

$1M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Hughes Owen

director

May 11, 2026Award11,25011.3KForm 4 ↗

Murphy Christopher M.

Chief Financial Officer

May 11, 2026Award25,76525.8KForm 4 ↗

Faga Daniel

President, CEO

Apr 20, 2026D-Return11,000$31.12$342.3K11.0KForm 4 ↗

Orwin John A

director

Apr 20, 2026Award16,510$10.87$179.5K16.5KForm 4 ↗

Orwin John A

director

Apr 20, 2026D-Return16,510$14.83$244.8K16.5KForm 4 ↗

Orwin John A

director

Apr 20, 2026D-Return16,510$21.19$349.8K16.5KForm 4 ↗

Orwin John A

director

Apr 20, 2026Award16,510$15.53$256.4K16.5KForm 4 ↗

Orwin John A

director

Apr 20, 2026D-Return10,600$19.50$206.7K10.6KForm 4 ↗

Orwin John A

director

Apr 20, 2026Award10,600$14.29$151.5K10.6KForm 4 ↗

Orwin John A

director

Apr 20, 2026D-Return8,250$43.91$362.3K8.3KForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

AnaptysBio, Inc. (ANAB) is primarily owned by institutional investors, who hold approximately 73.5% of total shares outstanding. Company insiders own approximately 6.56%, while retail and public investors account for the remaining 19.97%.

The largest institutional shareholder of AnaptysBio, Inc. is ECOR1 CAPITAL, LLC, holding approximately 7.88 million shares — equal to 27.35% of outstanding shares — as of September 30, 2025.

A total of 177 institutional investors currently hold ANAB stock, with a combined institutional value of approximately $980,500,660 as of the most recent 13F filing period.

Frequently asked questions

ANAB ownership

AnaptysBio, Inc. (ANAB) is primarily owned by institutional investors, who hold approximately 73.5% of shares. The largest shareholder is ECOR1 CAPITAL, LLC with a 27.35% stake. Company insiders hold 6.56%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns ANAB stockANAB ownership structureSEC Form 13F institutional holdingsANAB float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025