Companies: 10,795·Total market cap: $144.5T
Annexon, Inc.

Annexon, Inc.

ANNXNASDAQHealthcare● Active
$5.31
+$0.02(+0.38%)
Market Cap$635049721
P/E Ratio
52W High$7.18
52W Low$1.85

Annexon, Inc. (ANNX) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · ANNX · as of Mar 31, 2025

Ownership Breakdown

Institutions 83.42%
Insiders 0%
Public 23.74%

152

Institutional Holders

▼ 4 vs Q4

$192.19M

Total Inst. Value

▼ $382.44M vs Q4

119.60M

Shares Outstanding

freeFloat 107.16%

99.76M

13F Shares Held

▼ 12.41M vs Q4

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

ANNX largest shareholders · institutional ownership

Q1 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

FMR LLC

pharmaceutical preparations

13.26M8.95%

8.95%

$25.60BMay 12, 2025 962.1K

BLACKROCK, INC.

pharmaceutical preparations

8.53M5.76%

5.76%

$16.46BMay 2, 2025 40.3K

BVF INC/IL

pharmaceutical preparations

7.00M4.73%

4.73%

$13.51BMay 15, 2025— held

REDMILE GROUP, LLC

pharmaceutical preparations

6.30M4.25%

4.25%

$12.16BMay 15, 2025— held

VANGUARD GROUP INC

pharmaceutical preparations

5.38M3.63%

3.63%

$10.38BMay 9, 2025 167.3K

BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC

pharmaceutical preparations

5.25M3.54%

3.54%

$10.13BMay 15, 2025— held

BELLEVUE GROUP AG

pharmaceutical preparations

5.16M3.48%

3.48%

$9.95BMay 14, 2025— held

LOGOS GLOBAL MANAGEMENT LP

pharmaceutical preparations

4.00M2.70%

2.70%

$7.72BMay 15, 2025 1.45M

AMERIPRISE FINANCIAL INC

pharmaceutical preparations

3.99M2.69%

2.69%

$7.69BMay 14, 2025 3.06M

SIO CAPITAL MANAGEMENT, LLC

pharmaceutical preparations

3.40M2.29%

2.29%

$6.56BMay 15, 2025 1.03M

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q1 2025 vs prior quarter

Q1 2025

Net institutional sentimentBullish — more buying than selling

27

Increased

+10.48M shares

2

New Positions

first time holders

13

Decreased

−6.07M shares

0

Sold Out

fully exited

Net shares change (top 50)

+4.42M

+10.48M / −6.07M

Net new holders

+16

2 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

ANNX insider trading · insider activity

Source: SEC Form 4

Buy 44%Active transactions only56% Sell

Insiders have been net buyers of shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

3

Buy transactions

0

Sell transactions

0.00

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Satter Muneer A

director

May 28, 2026Purchase613,497$5.41$3.32M10.34MForm 4 ↗

Carson William H.

director

May 11, 2026Purchase8,000$5.78$46.2K78.4KForm 4 ↗

Carson William H.

director

Apr 10, 2026Purchase8,000$6.20$49.6K70.4KForm 4 ↗

Carson William H.

director

Mar 10, 2026Purchase8,000$5.67$45.4K62.4KForm 4 ↗

Dananberg Jamie

CHIEF MEDICAL OFFICER

Mar 2, 2026Sale5,820$5.43$31.6K123.6KForm 4 ↗

Overdorf Michael

EVP & CHIEF BUSINESS OFFICER

Mar 2, 2026Sale4,339$5.42$23.5K182.6KForm 4 ↗

Yednock Ted

EVP & CHIEF INNOVATION OFFICER

Mar 2, 2026Sale5,566$5.42$30.2K154.2KForm 4 ↗

ARTIS DEAN RICHARD

EVP & CHIEF SCIENTIFIC OFFICER

Mar 2, 2026Sale5,894$5.43$32.0K180.1KForm 4 ↗

Lew Jennifer

EVP & CHIEF FINANCIAL OFFICER

Mar 2, 2026Sale5,565$5.42$30.2K170.7KForm 4 ↗

Love Douglas

PRESIDENT AND CEO

Feb 19, 2026Award1,250,000$5.10$6.38M1.25MForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Annexon, Inc. (ANNX) is primarily owned by institutional investors, who hold approximately 83.4% of total shares outstanding. Company insiders own approximately 0.00%, while retail and public investors account for the remaining 23.74%.

The largest institutional shareholder of Annexon, Inc. is FMR LLC, holding approximately 13.26 million shares — equal to 8.95% of outstanding shares — as of March 31, 2025.

A total of 152 institutional investors currently hold ANNX stock, with a combined institutional value of approximately $192,194,831 as of the most recent 13F filing period.

Frequently asked questions

ANNX ownership

Annexon, Inc. (ANNX) is primarily owned by institutional investors, who hold approximately 83.4% of shares. The largest shareholder is FMR LLC with a 8.95% stake. Company insiders hold 0.00%. Data sourced from SEC Form 13F as of March 31, 2025.

who owns ANNX stockANNX ownership structureSEC Form 13F institutional holdingsANNX float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of March 31, 2025