Companies: 10,795·Total market cap: $144.5T
Castle Biosciences, Inc.

Castle Biosciences, Inc.

CSTLNASDAQHealthcare● Active
$20.12
$-0.89(-4.24%)
Market Cap$610238634
P/E Ratio
52W High$44.28
52W Low$14.59

Castle Biosciences, Inc. (CSTL) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · CSTL · as of Mar 31, 2025

Ownership Breakdown

Institutions 85.3%
Insiders 11.75%
Public 2.95%

182

Institutional Holders

▼ 25 vs Q4

$516.29M

Total Inst. Value

▼ $190.12M vs Q4

30.33M

Shares Outstanding

freeFloat 88.25%

25.87M

13F Shares Held

▼ 635,412 vs Q4

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

CSTL largest shareholders · institutional ownership

Q1 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

BLACKROCK, INC.

services-medical laboratories

2.98M10.43%

10.43%

$59.73BMay 2, 2025 62.2K

VANGUARD GROUP INC

services-medical laboratories

2.05M7.16%

7.16%

$40.99BMay 9, 2025 215.0K

PRINCIPAL FINANCIAL GROUP INC

services-medical laboratories

1.47M5.13%

5.13%

$29.39BApr 28, 2025 32.2K

PORTOLAN CAPITAL MANAGEMENT, LLC

services-medical laboratories

1.27M4.42%

4.42%

$25.33BMay 15, 2025 488.6K

DIMENSIONAL FUND ADVISORS LP

services-medical laboratories

1.20M4.20%

4.20%

$24.03BMay 13, 2025 200.8K

WASATCH ADVISORS LP

services-medical laboratories

998.5K3.49%

3.49%

$19.99BMay 15, 2025 797.6K

WELLINGTON MANAGEMENT GROUP LLP

services-medical laboratories

828.5K2.90%

2.90%

$16.59BMay 13, 2025 106.4K

STATE STREET CORP

services-medical laboratories

715.0K2.50%

2.50%

$14.31BMay 15, 2025 4.8K

RENAISSANCE TECHNOLOGIES LLC

services-medical laboratories

701.2K2.45%

2.45%

$14.04BMay 14, 2025 16.2K

ACADIAN ASSET MANAGEMENT LLC

services-medical laboratories

676.1K2.36%

2.36%

$13.53BMay 21, 2025 267.4K

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q1 2025 vs prior quarter

Q1 2025

Net institutional sentimentBullish — more buying than selling

30

Increased

+3.22M shares

3

New Positions

first time holders

16

Decreased

−2.98M shares

0

Sold Out

fully exited

Net shares change (top 50)

+233.5K

+3.22M / −2.98M

Net new holders

+17

3 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

CSTL insider trading · insider activity

Source: SEC Form 4

5

Buy transactions

29

Sell transactions

0.17

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Olson Tiffany

director

May 28, 2026Award11,76611.8KForm 4 ↗

Goldberg Ellen

director

May 28, 2026Award11,76611.8KForm 4 ↗

Harrison Miles

director

May 28, 2026Award11,76611.8KForm 4 ↗

Cotton Rodney

director

May 28, 2026Award11,76611.8KForm 4 ↗

Caple Kim

director

May 28, 2026Award11,76611.8KForm 4 ↗

BRADBURY DANIEL

director

May 28, 2026Award11,76611.8KForm 4 ↗

Cole G Bradley

director

May 28, 2026Award11,76611.8KForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Castle Biosciences, Inc. (CSTL) is primarily owned by institutional investors, who hold approximately 85.3% of total shares outstanding. Company insiders own approximately 11.75%, while retail and public investors account for the remaining 2.95%.

The largest institutional shareholder of Castle Biosciences, Inc. is BLACKROCK, INC., holding approximately 2.98 million shares — equal to 10.43% of outstanding shares — as of March 31, 2025.

A total of 182 institutional investors currently hold CSTL stock, with a combined institutional value of approximately $516,286,662 as of the most recent 13F filing period.

Frequently asked questions

CSTL ownership

Castle Biosciences, Inc. (CSTL) is primarily owned by institutional investors, who hold approximately 85.3% of shares. The largest shareholder is BLACKROCK, INC. with a 10.43% stake. Company insiders hold 11.75%. Data sourced from SEC Form 13F as of March 31, 2025.

who owns CSTL stockCSTL ownership structureSEC Form 13F institutional holdingsCSTL float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of March 31, 2025