Companies: 10,795·Total market cap: $144.5T
Dyne Therapeutics, Inc.

Dyne Therapeutics, Inc.

DYNNASDAQHealthcare● Active
$17.04
$-1.37(-7.44%)
Market Cap$2.8B
P/E Ratio
52W High$25
52W Low$8.06

Dyne Therapeutics, Inc. (DYN) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · DYN · as of Sep 30, 2025

Ownership Breakdown

Institutions 94.27%
Insiders 20.15%
Public 0%

217

Institutional Holders

▲ 16 vs Q2

$1.97B

Total Inst. Value

▲ $746.55M vs Q2

165.31M

Shares Outstanding

freeFloat 79.85%

155.84M

13F Shares Held

▲ 27.22M vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

DYN largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

JANUS HENDERSON GROUP PLC

pharmaceutical preparations

14.75M12.95%

12.95%

$186.49BNov 14, 2025 5.31M

VANGUARD GROUP INC

pharmaceutical preparations

9.76M8.57%

8.57%

$123.47BNov 7, 2025 2.11M

BLACKROCK, INC.

pharmaceutical preparations

9.63M8.46%

8.46%

$121.88BNov 12, 2025 1.56M

ATLAS VENTURE LIFE SCIENCE ADVISORS, LLC

pharmaceutical preparations

9.13M8.02%

8.02%

$115.50BNov 13, 2025— held

FCPM III SERVICES B.V.

pharmaceutical preparations

5.46M4.80%

4.80%

$69.11BNov 14, 2025— held

FMR LLC

pharmaceutical preparations

5.40M4.74%

4.74%

$68.33BNov 13, 2025 108.5K

STATE STREET CORP

pharmaceutical preparations

5.27M4.63%

4.63%

$66.65BNov 14, 2025 1.91M

SIREN, L.L.C.

pharmaceutical preparations

4.73M4.15%

4.15%

$59.82BNov 13, 2025 107.3K

TCG CROSSOVER MANAGEMENT, LLC

pharmaceutical preparations

4.62M4.05%

4.05%

$58.38BNov 17, 2025 848.5K

ADAGE CAPITAL PARTNERS GP, L.L.C.

pharmaceutical preparations

3.55M3.12%

3.12%

$44.96BNov 14, 2025 363.0K

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBullish — more buying than selling

38

Increased

+36.56M shares

2

New Positions

first time holders

5

Decreased

−1.76M shares

0

Sold Out

fully exited

Net shares change (top 50)

+34.80M

+36.56M / −1.76M

Net new holders

+35

2 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

DYN insider trading · insider activity

Source: SEC Form 4

Buy 15%Active transactions only85% Sell

Insiders have been primarily selling shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

3

Buy transactions

61

Sell transactions

0.05

Buy/Sell ratio

$2M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Posner Brian S

director

Jun 3, 2026Purchase2,500$17.48$43.7K22.5KForm 4 ↗

Posner Brian S

director

May 26, 2026Purchase2,000$18.21$36.4K20.0KForm 4 ↗

Posner Brian S

director

May 20, 2026Purchase2,500$17.12$42.8K18.0KForm 4 ↗

Friedl-Naderer Johanna

Chief Commercial Officer

May 13, 2026Sale228$18.36$4.2K154.4KForm 4 ↗

Kerr Douglas

Chief Medical Officer

May 13, 2026Sale1,564$18.36$28.7K170.0KForm 4 ↗

Lucera Erick

Chief Financial Officer

May 13, 2026Sale1,448$18.36$26.6K123.9KForm 4 ↗

Cox John

CEO & President

May 13, 2026Sale3,311$18.36$60.8K370.8KForm 4 ↗

Rhodes Jason P

director

May 4, 2026Sale6,241$18.00$112.3K4.93MForm 4 ↗

Rhodes Jason P

director

May 5, 2026Sale6,081$18.03$109.6K4.93MForm 4 ↗

Rhodes Jason P

director

May 6, 2026Sale43,621$18.18$793.0K4.88MForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Dyne Therapeutics, Inc. (DYN) is primarily owned by institutional investors, who hold approximately 94.3% of total shares outstanding. Company insiders own approximately 20.15%, while retail and public investors account for the remaining 0.00%.

The largest institutional shareholder of Dyne Therapeutics, Inc. is JANUS HENDERSON GROUP PLC, holding approximately 14.75 million shares — equal to 12.95% of outstanding shares — as of September 30, 2025.

A total of 217 institutional investors currently hold DYN stock, with a combined institutional value of approximately $1.97 billion as of the most recent 13F filing period.

Frequently asked questions

DYN ownership

Dyne Therapeutics, Inc. (DYN) is primarily owned by institutional investors, who hold approximately 94.3% of shares. The largest shareholder is JANUS HENDERSON GROUP PLC with a 12.95% stake. Company insiders hold 20.15%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns DYN stockDYN ownership structureSEC Form 13F institutional holdingsDYN float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025