Companies: 10,795·Total market cap: $144.5T
Fulcrum Therapeutics, Inc.

Fulcrum Therapeutics, Inc.

FULCNASDAQHealthcare● Active
$3.48
$-0.21(-5.73%)
Market Cap$188231840
P/E Ratio
52W High$15.74
52W Low$2.83

Fulcrum Therapeutics, Inc. (FULC) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · FULC · as of Sep 30, 2025

Ownership Breakdown

Institutions 99.52%
Insiders 11.29%
Public 0%

134

Institutional Holders

▲ 5 vs Q2

$496.11M

Total Inst. Value

▲ $121.61M vs Q2

54.11M

Shares Outstanding

freeFloat 88.71%

53.85M

13F Shares Held

▼ 546,540 vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

FULC largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

RA CAPITAL MANAGEMENT, L.P.

pharmaceutical preparations

10.23M16.36%

16.36%

$94.11BNov 14, 2025— held

SUVRETTA CAPITAL MANAGEMENT, LLC

pharmaceutical preparations

5.38M8.60%

8.60%

$49.51BNov 14, 2025 298.1K

TCG CROSSOVER MANAGEMENT, LLC

pharmaceutical preparations

5.25M8.39%

8.39%

$48.30BNov 17, 2025— held

NANTAHALA CAPITAL MANAGEMENT, LLC

pharmaceutical preparations

4.67M7.47%

7.47%

$42.97BNov 14, 2025 382.5K

BLACKROCK, INC.

pharmaceutical preparations

3.71M5.93%

5.93%

$34.10BNov 12, 2025 672.3K

VANGUARD GROUP INC

pharmaceutical preparations

3.00M4.80%

4.80%

$27.60BNov 7, 2025 147.0K

ADAGE CAPITAL PARTNERS GP, L.L.C.

pharmaceutical preparations

2.43M3.89%

3.89%

$22.37BNov 14, 2025 2.16M

BALYASNY ASSET MANAGEMENT L.P.

pharmaceutical preparations

1.45M2.32%

2.32%

$13.34BNov 14, 2025 112.3K

D. E. SHAW & CO., INC.

pharmaceutical preparations

1.45M2.32%

2.32%

$13.33BNov 14, 2025 272.7K

DIMENSIONAL FUND ADVISORS LP

pharmaceutical preparations

1.30M2.08%

2.08%

$11.95BNov 12, 2025 73.3K

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBullish — more buying than selling

24

Increased

+5.87M shares

3

New Positions

first time holders

17

Decreased

−4.89M shares

0

Sold Out

fully exited

Net shares change (top 50)

+980.9K

+5.87M / −4.89M

Net new holders

+10

3 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

FULC insider trading · insider activity

Source: SEC Form 4

Buy 0%Active transactions only100% Sell

Insiders have been primarily selling shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

4

Buy transactions

3

Sell transactions

1.33

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Lehrer-Graiwer Joshua

director

Apr 23, 2026Award64,000$8.08$517.1K64.0KForm 4 ↗

Gould Robert J

director

Jan 2, 2026Sale15,000$10.87$163.1K469.9KForm 4 ↗

Musso Alan A

Chief Financial Officer

Feb 2, 2026Award170,000$10.72$1.82M170.0KForm 4 ↗

Oltmans Curtis Gale

Chief Legal Officer

Feb 2, 2026Award170,000$10.72$1.82M170.0KForm 4 ↗

Gould Robert J

director

Feb 2, 2026Sale15,000$10.72$160.9K454.9KForm 4 ↗

Tourangeau Greg

Principal Accounting Officer

Feb 2, 2026Award57,000$10.72$611.0K57.0KForm 4 ↗

Sapir Alex

See Remarks

Feb 2, 2026Award650,000$10.72$6.97M650.0KForm 4 ↗

Gould Robert J

director

Jan 2, 2026Sale15,000$11.87$178.1K469.9KForm 4 ↗

Oltmans Curtis Gale

Chief Legal Officer

Dec 15, 2025Sale3,452$12.92$44.6K10.3KForm 4 ↗

RA CAPITAL MANAGEMENT, L.P.

10 percent owner

Dec 8, 2025Sale1,377,020$13.33$18.36M8.85MForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Fulcrum Therapeutics, Inc. (FULC) is primarily owned by institutional investors, who hold approximately 99.5% of total shares outstanding. Company insiders own approximately 11.29%, while retail and public investors account for the remaining 0.00%.

The largest institutional shareholder of Fulcrum Therapeutics, Inc. is RA CAPITAL MANAGEMENT, L.P., holding approximately 10.23 million shares — equal to 16.36% of outstanding shares — as of September 30, 2025.

A total of 134 institutional investors currently hold FULC stock, with a combined institutional value of approximately $496,105,089 as of the most recent 13F filing period.

Frequently asked questions

FULC ownership

Fulcrum Therapeutics, Inc. (FULC) is primarily owned by institutional investors, who hold approximately 99.5% of shares. The largest shareholder is RA CAPITAL MANAGEMENT, L.P. with a 16.36% stake. Company insiders hold 11.29%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns FULC stockFULC ownership structureSEC Form 13F institutional holdingsFULC float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025