Companies: 10,795·Total market cap: $144.5T
Krystal Biotech, Inc.

Krystal Biotech, Inc.

KRYSNASDAQHealthcare● Active
$304.52
+$3.52(+1.17%)
Market Cap$9.0B
P/E Ratio
52W High$319.48
52W Low$127.99

Krystal Biotech, Inc. (KRYS) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · KRYS · as of Mar 31, 2025

Ownership Breakdown

Institutions 93.68%
Insiders 20.72%
Public 0%

316

Institutional Holders

▲ 31 vs Q4

$4.98B

Total Inst. Value

▲ $627.62M vs Q4

29.48M

Shares Outstanding

freeFloat 79.28%

27.62M

13F Shares Held

▼ 156,039 vs Q4

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

KRYS largest shareholders · institutional ownership

Q1 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

FMR LLC

biological products, (no diagnostic substances)

4.32M15.00%

15.00%

$779.05BMay 12, 2025 6.8K

BLACKROCK, INC.

biological products, (no diagnostic substances)

3.94M13.68%

13.68%

$710.95BMay 2, 2025 90.7K

VANGUARD GROUP INC

biological products, (no diagnostic substances)

2.83M9.80%

9.80%

$509.40BMay 9, 2025 53.2K

AVORO CAPITAL ADVISORS LLC

biological products, (no diagnostic substances)

2.73M9.48%

9.48%

$492.40BMay 15, 2025 102.2K

STATE STREET CORP

biological products, (no diagnostic substances)

1.23M4.26%

4.26%

$221.18BMay 15, 2025 52.3K

CAPITAL WORLD INVESTORS

biological products, (no diagnostic substances)

954.5K3.31%

3.31%

$172.09BMay 12, 2025 75.3K

REDMILE GROUP, LLC

biological products, (no diagnostic substances)

737.7K2.56%

2.56%

$133.00BMay 15, 2025 15.5K

FRAZIER LIFE SCIENCES MANAGEMENT, L.P.

biological products, (no diagnostic substances)

688.5K2.39%

2.39%

$124.13BMay 15, 2025 100.0K

GEODE CAPITAL MANAGEMENT, LLC

biological products, (no diagnostic substances)

612.4K2.13%

2.13%

$110.43BMay 13, 2025 20.8K

UBS ASSET MANAGEMENT AMERICAS INC

biological products, (no diagnostic substances)

575.5K2.00%

2.00%

$103.76BMay 19, 2025 365.3K

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q1 2025 vs prior quarter

Q1 2025

Net institutional sentimentBearish — more selling than buying

19

Increased

+1.27M shares

3

New Positions

first time holders

27

Decreased

−913.4K shares

0

Sold Out

fully exited

Net shares change (top 50)

+352.4K

+1.27M / −913.4K

Net new holders

-5

3 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

KRYS insider trading · insider activity

Source: SEC Form 4

Buy 0%Active transactions only100% Sell

Insiders have been primarily selling shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

0

Buy transactions

23

Sell transactions

0.00

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Krishnan Suma

President, R&D

Jun 4, 2026Sale320$300.75$96.2K1.40MForm 4 ↗

Krishnan Suma

President, R&D

Jun 4, 2026Sale593$302.25$179.2K1.40MForm 4 ↗

Krishnan Suma

President, R&D

Jun 4, 2026Sale247$303.17$74.9K1.40MForm 4 ↗

Krishnan Suma

President, R&D

Jun 4, 2026Sale400$304.89$122.0K1.40MForm 4 ↗

Krishnan Suma

President, R&D

Jun 4, 2026Sale480$305.87$146.8K1.40MForm 4 ↗

Krishnan Suma

President, R&D

Jun 4, 2026Sale1,348$307.09$414.0K1.40MForm 4 ↗

Krishnan Suma

President, R&D

Jun 4, 2026Sale12,729$307.81$3.92M1.39MForm 4 ↗

Krishnan Suma

President, R&D

Jun 4, 2026Sale3,803$308.89$1.17M1.38MForm 4 ↗

Krishnan Suma

President, R&D

Jun 4, 2026Sale2,801$309.95$868.2K1.38MForm 4 ↗

Krishnan Suma

President, R&D

Jun 4, 2026Sale2,039$310.94$634.0K1.38MForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Krystal Biotech, Inc. (KRYS) is primarily owned by institutional investors, who hold approximately 93.7% of total shares outstanding. Company insiders own approximately 20.72%, while retail and public investors account for the remaining 0.00%.

The largest institutional shareholder of Krystal Biotech, Inc. is FMR LLC, holding approximately 4.32 million shares — equal to 15.00% of outstanding shares — as of March 31, 2025.

A total of 316 institutional investors currently hold KRYS stock, with a combined institutional value of approximately $4.98 billion as of the most recent 13F filing period.

Frequently asked questions

KRYS ownership

Krystal Biotech, Inc. (KRYS) is primarily owned by institutional investors, who hold approximately 93.7% of shares. The largest shareholder is FMR LLC with a 15.00% stake. Company insiders hold 20.72%. Data sourced from SEC Form 13F as of March 31, 2025.

who owns KRYS stockKRYS ownership structureSEC Form 13F institutional holdingsKRYS float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of March 31, 2025