
Lexicon Pharmaceuticals, Inc.
Lexicon Pharmaceuticals, Inc. (LXRX) Stock Ownership
Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.
SEC 13F · FMP · LXRX · as of Mar 31, 2025
Ownership Breakdown
132
Institutional Holders
$122.49M
Total Inst. Value
▼ $97.64M vs Q4
444.20M
Shares Outstanding
freeFloat 47.17%
265.82M
13F Shares Held
▼ 31.84M vs Q4
Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.
Top Institutional Holders
LXRX largest shareholders · institutional ownership
Q1 2025 · SEC 13F
Showing top 10 holders
| Holder | Shares | % Owned | Weight | Value | Reported | Change |
|---|---|---|---|---|---|---|
ARTAL GROUP S.A. pharmaceutical preparations | 136.18M | 37.61% | 37.61% | $62.64B | May 14, 2025 | — held |
SIREN, L.L.C. pharmaceutical preparations | 38.92M | 10.75% | 10.75% | $17.93B | May 23, 2025 | — held |
FMR LLC pharmaceutical preparations | 34.54M | 9.54% | 9.54% | $15.92B | May 12, 2025 | ▼ 17.43M |
BLACKROCK, INC. pharmaceutical preparations | 10.01M | 2.77% | 2.77% | $4.61B | May 2, 2025 | ▼ 320.2K |
VANGUARD GROUP INC pharmaceutical preparations | 9.56M | 2.64% | 2.64% | $4.41B | May 9, 2025 | ▼ 324.6K |
SCHONFELD STRATEGIC ADVISORS LLC pharmaceutical preparations | 8.21M | 2.27% | 2.27% | $3.78B | May 15, 2025 | ▲ 654.4K |
GEODE CAPITAL MANAGEMENT, LLC pharmaceutical preparations | 3.69M | 1.02% | 1.02% | $1.70B | May 13, 2025 | ▲ 168.0K |
STATE STREET CORP pharmaceutical preparations | 2.61M | 72.02% | 72.02% | $1.20B | May 15, 2025 | ▼ 110.7K |
CIBC PRIVATE WEALTH GROUP, LLC pharmaceutical preparations | 2.24M | 61.87% | 61.87% | $1.12B | May 14, 2025 | ▲ 2.24M |
UBS GROUP AG pharmaceutical preparations | 2.10M | 57.87% | 57.87% | $965.95M | May 13, 2025 | ▲ 1.41M |
Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).
Institutional Activity
Q1 2025 vs prior quarter
Q1 2025
21
Increased
+6.88M shares7
New Positions
first time holders18
Decreased
−25.34M shares0
Sold Out
fully exitedNet shares change (top 50)
18.46M
+6.88M / −25.34M
Net new holders
+10
7 new / 0 exited
Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).
Insider Buying vs Selling
LXRX insider trading · insider activity
Source: SEC Form 4
23
Buy transactions
8
Sell transactions
2.88
Buy/Sell ratio
$1M
Total disposed
Recent Insider Transactions
Showing 10 most recent · Common Stock only
| Name · Role | Date | Type | Shares | Price | Value | After Trans. | Filing |
|---|---|---|---|---|---|---|---|
Artal Participations S.a r.l.
| Apr 30, 2026 | Award | 408,434.7 | — | — | 408.4K | Form 4 ↗ |
Amouyal Philippe director | May 1, 2026 | Award | 43,478 | $1.61 | $70.0K | 43.5K | Form 4 ↗ |
Amouyal Philippe director | May 1, 2026 | Award | 35,714 | — | — | 35.7K | Form 4 ↗ |
SOBECKI CHRISTOPHER J director | May 1, 2026 | Award | 43,478 | $1.61 | $70.0K | 43.5K | Form 4 ↗ |
Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.
About institutional & insider ownership
Lexicon Pharmaceuticals, Inc. (LXRX) is primarily owned by institutional investors, who hold approximately 59.8% of total shares outstanding. Company insiders own approximately 52.83%, while retail and public investors account for the remaining 0.00%.
The largest institutional shareholder of Lexicon Pharmaceuticals, Inc. is ARTAL GROUP S.A., holding approximately 136.18 million shares — equal to 37.61% of outstanding shares — as of March 31, 2025.
A total of 132 institutional investors currently hold LXRX stock, with a combined institutional value of approximately $122,486,776 as of the most recent 13F filing period.
Frequently asked questions
LXRX ownershipLexicon Pharmaceuticals, Inc. (LXRX) is primarily owned by institutional investors, who hold approximately 59.8% of shares. The largest shareholder is ARTAL GROUP S.A. with a 37.61% stake. Company insiders hold 52.83%. Data sourced from SEC Form 13F as of March 31, 2025.