Companies: 10,795·Total market cap: $144.5T
Lexicon Pharmaceuticals, Inc.

Lexicon Pharmaceuticals, Inc.

LXRXNASDAQHealthcare● Active
$1.90
$-0.01(-0.62%)
Market Cap$843172847
P/E Ratio
52W High$2.53
52W Low$0.64

Lexicon Pharmaceuticals, Inc. (LXRX) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · LXRX · as of Mar 31, 2025

Ownership Breakdown

Institutions 59.84%
Insiders 52.83%
Public 0%

132

Institutional Holders

$122.49M

Total Inst. Value

▼ $97.64M vs Q4

444.20M

Shares Outstanding

freeFloat 47.17%

265.82M

13F Shares Held

▼ 31.84M vs Q4

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

LXRX largest shareholders · institutional ownership

Q1 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

ARTAL GROUP S.A.

pharmaceutical preparations

136.18M37.61%

37.61%

$62.64BMay 14, 2025— held

SIREN, L.L.C.

pharmaceutical preparations

38.92M10.75%

10.75%

$17.93BMay 23, 2025— held

FMR LLC

pharmaceutical preparations

34.54M9.54%

9.54%

$15.92BMay 12, 2025 17.43M

BLACKROCK, INC.

pharmaceutical preparations

10.01M2.77%

2.77%

$4.61BMay 2, 2025 320.2K

VANGUARD GROUP INC

pharmaceutical preparations

9.56M2.64%

2.64%

$4.41BMay 9, 2025 324.6K

SCHONFELD STRATEGIC ADVISORS LLC

pharmaceutical preparations

8.21M2.27%

2.27%

$3.78BMay 15, 2025 654.4K

GEODE CAPITAL MANAGEMENT, LLC

pharmaceutical preparations

3.69M1.02%

1.02%

$1.70BMay 13, 2025 168.0K

STATE STREET CORP

pharmaceutical preparations

2.61M72.02%

72.02%

$1.20BMay 15, 2025 110.7K

CIBC PRIVATE WEALTH GROUP, LLC

pharmaceutical preparations

2.24M61.87%

61.87%

$1.12BMay 14, 2025 2.24M

UBS GROUP AG

pharmaceutical preparations

2.10M57.87%

57.87%

$965.95MMay 13, 2025 1.41M

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q1 2025 vs prior quarter

Q1 2025

Net institutional sentimentBullish — more buying than selling

21

Increased

+6.88M shares

7

New Positions

first time holders

18

Decreased

−25.34M shares

0

Sold Out

fully exited

Net shares change (top 50)

18.46M

+6.88M / −25.34M

Net new holders

+10

7 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

LXRX insider trading · insider activity

Source: SEC Form 4

23

Buy transactions

8

Sell transactions

2.88

Buy/Sell ratio

$1M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

Artal Participations S.a r.l.

Apr 30, 2026Award408,434.7408.4KForm 4 ↗

Amouyal Philippe

director

May 1, 2026Award43,478$1.61$70.0K43.5KForm 4 ↗

Amouyal Philippe

director

May 1, 2026Award35,71435.7KForm 4 ↗

SOBECKI CHRISTOPHER J

director

May 1, 2026Award43,478$1.61$70.0K43.5KForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Lexicon Pharmaceuticals, Inc. (LXRX) is primarily owned by institutional investors, who hold approximately 59.8% of total shares outstanding. Company insiders own approximately 52.83%, while retail and public investors account for the remaining 0.00%.

The largest institutional shareholder of Lexicon Pharmaceuticals, Inc. is ARTAL GROUP S.A., holding approximately 136.18 million shares — equal to 37.61% of outstanding shares — as of March 31, 2025.

A total of 132 institutional investors currently hold LXRX stock, with a combined institutional value of approximately $122,486,776 as of the most recent 13F filing period.

Frequently asked questions

LXRX ownership

Lexicon Pharmaceuticals, Inc. (LXRX) is primarily owned by institutional investors, who hold approximately 59.8% of shares. The largest shareholder is ARTAL GROUP S.A. with a 37.61% stake. Company insiders hold 52.83%. Data sourced from SEC Form 13F as of March 31, 2025.

who owns LXRX stockLXRX ownership structureSEC Form 13F institutional holdingsLXRX float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of March 31, 2025