Companies: 10,795·Total market cap: $144.5T
Metsera, Inc.

Metsera, Inc.

MTSRNASDAQHealthcare
$70.50
$-0.25(-0.35%)
Market Cap$7.4B
P/E Ratio
52W High$83.8599
52W Low$12.3

Metsera, Inc. (MTSR) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · MTSR · as of Sep 30, 2025

Ownership Breakdown

Institutions 61.46%
Insiders 54.31%
Public 0%

167

Institutional Holders

▲ 55 vs Q2

$3.39B

Total Inst. Value

▲ $1.65B vs Q2

105.38M

Shares Outstanding

freeFloat 45.69%

64.76M

13F Shares Held

▲ 3.65M vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

MTSR largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

FMR LLC

pharmaceutical preparations

13.89M13.25%

13.25%

$726.97BNov 13, 2025 1.87M

VANGUARD GROUP INC

pharmaceutical preparations

5.82M5.55%

5.55%

$304.82BNov 7, 2025 4.33M

JANUS HENDERSON GROUP PLC

pharmaceutical preparations

5.35M5.10%

5.10%

$280.08BNov 14, 2025 1.96M

BLACKROCK, INC.

pharmaceutical preparations

3.84M3.66%

3.66%

$200.70BNov 12, 2025 2.60M

ALPHABET INC.

pharmaceutical preparations

3.78M3.61%

3.61%

$197.99BNov 7, 2025 1.18M

VR ADVISER, LLC

pharmaceutical preparations

3.75M3.58%

3.58%

$196.27BNov 14, 2025— held

WELLINGTON MANAGEMENT GROUP LLP

pharmaceutical preparations

3.66M3.49%

3.49%

$191.50BNov 14, 2025 232.0K

SOFTBANK GROUP CORP.

pharmaceutical preparations

3.65M3.48%

3.48%

$191.25BNov 14, 2025 1.17M

HBK INVESTMENTS L P

pharmaceutical preparations

3.20M3.05%

3.05%

$167.46BNov 14, 2025NEW

STATE STREET CORP

pharmaceutical preparations

2.51M2.39%

2.39%

$131.40BNov 14, 2025 1.91M

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBullish — more buying than selling

23

Increased

+14.88M shares

13

New Positions

first time holders

6

Decreased

−5.12M shares

0

Sold Out

fully exited

Net shares change (top 50)

+9.76M

+14.88M / −5.12M

Net new holders

+30

13 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

MTSR insider trading · insider activity

Source: SEC Form 4

14

Buy transactions

38

Sell transactions

0.37

Buy/Sell ratio

$77M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

FMR LLC

See Remark 1

Nov 13, 2025J-Other2,230,450$0.00$22.3050Form 4 ↗

ARCH Venture Partners XII, LLC

Nov 13, 2025D-Return8,313,680$0.00$83.1370Form 4 ↗

Marso Steven

CHIEF MEDICAL OFFICER

Nov 13, 2025D-Return17,000$0.00$0.170Form 4 ↗

Marso Steven

CHIEF MEDICAL OFFICER

Nov 13, 2025D-Return21,279$0.26$5.5K0Form 4 ↗

Marso Steven

CHIEF MEDICAL OFFICER

Nov 13, 2025D-Return120,000$29.25$3.51M0Form 4 ↗

BERNS PAUL L

director

Nov 13, 2025D-Return24,188$29.25$707.5K0Form 4 ↗

BERNS PAUL L

director

Nov 13, 2025D-Return223,430$8.18$1.83M0Form 4 ↗

BERNS PAUL L

director

Nov 13, 2025D-Return957,559$0.00$9.5760Form 4 ↗

Lang Matthew

CHIEF LEGAL OFFICER

Nov 13, 2025D-Return12,500$0.00$0.1250Form 4 ↗

Lang Matthew

CHIEF LEGAL OFFICER

Nov 13, 2025D-Return46,875$29.25$1.37M0Form 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Metsera, Inc. (MTSR) is primarily owned by institutional investors, who hold approximately 61.5% of total shares outstanding. Company insiders own approximately 54.31%, while retail and public investors account for the remaining 0.00%.

The largest institutional shareholder of Metsera, Inc. is FMR LLC, holding approximately 13.89 million shares — equal to 13.25% of outstanding shares — as of September 30, 2025.

A total of 167 institutional investors currently hold MTSR stock, with a combined institutional value of approximately $3.39 billion as of the most recent 13F filing period.

Frequently asked questions

MTSR ownership

Metsera, Inc. (MTSR) is primarily owned by institutional investors, who hold approximately 61.5% of shares. The largest shareholder is FMR LLC with a 13.25% stake. Company insiders hold 54.31%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns MTSR stockMTSR ownership structureSEC Form 13F institutional holdingsMTSR float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025