Companies: 10,795·Total market cap: $144.5T
Praxis Precision Medicines, Inc.

Praxis Precision Medicines, Inc.

PRAXNASDAQHealthcare● Active
$253.23
$-0.77(-0.30%)
Market Cap$5.4B
P/E Ratio
52W High$366.52
52W Low$37.19

Praxis Precision Medicines, Inc. (PRAX) Insider Trading

Form 4 buy vs sell counts, ratio, and sentiment — switch this quarter or last 12 months; chart and transactions below.

SEC EDGAR · FMP · PRAX · as of Jun 8, 2026

Activity summary

Buy transactions

0

P-Purchase only

Sell transactions

16

12 Months

Buy/Sell ratio

0.00

Buy/Sell (by trades)

Overall sentiment

BEARISH
↑ Buy 0%Active transactions only · RSU vesting excluded100% Sell ↓

Praxis Precision Medicines, Inc. insiders have been primarily selling shares over the past 12 Months. Selling activity is often driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment toward the company.

Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · Buy = P-Purchase only · Sell = S-Sale only

As of Jun 8, 2026

PRAX insider buying and selling by quarter

PRAX insider selling · PRAX insider buying stocks · quarterly insider activity

Total insider buying (incl. awards)Total insider selling
353K177K0
2025 Q2
2025 Q3
2025 Q4
2026 Q1

Mobile shows last 4Q · Desktop shows full 8Q

Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · last 8 quarters

As of Jun 8, 2026

Active insiders

Most active in past 12 months · PRAX ceo insider trading

Showing all insiders · Click a card to filter the transactions table below

Aggregated from reportingName · top 5 by trade count (12M) · no extra API

Recent insider transactions

PRAX executive sell shares · PRAX board member insider trading · PRAX insider trading SEC filing

Showing 61 most recent · Common Stock · Form 4 only

Scroll horizontally to see all columns

Mastrocola Lauren

PAO

Award

Date

May 14

Shares

127

Price

$167.94

Value

$21K

View Form 4 on SEC.gov

Nemiroff Alex

General Counsel and Secretary

Award

Date

May 14

Shares

78

Price

$167.94

Value

$13K

View Form 4 on SEC.gov

Kelly Timothy Edwin

CFO

Award

Date

May 14

Shares

121

Price

$167.94

Value

$20K

View Form 4 on SEC.gov

Sniecinski Megan

COO

Award

Date

May 14

Shares

89

Price

$167.94

Value

$15K

View Form 4 on SEC.gov

Souza Marcio

CEO · Director

Award

Date

May 14

Shares

126

Price

$167.94

Value

$21K

View Form 4 on SEC.gov

Arbuckle Stuart A

Director

Award

Date

Feb 6

Shares

478

Price

Value

View Form 4 on SEC.gov

Arbuckle Stuart A

Director

Award

Date

Feb 6

Shares

688

Price

Value

View Form 4 on SEC.gov

KINDLER JEFFREY B

Director

Award

Date

Feb 6

Shares

478

Price

Value

View Form 4 on SEC.gov

KINDLER JEFFREY B

Director

Award

Date

Feb 6

Shares

688

Price

Value

View Form 4 on SEC.gov

Mastrocola Lauren

PAO

Other

Date

Jan 12

Shares

344

Price

$275.74

Value

$95K

View Form 4 on SEC.gov

Sniecinski Megan

COO

Other

Date

Jan 12

Shares

885

Price

$275.74

Value

$244K

View Form 4 on SEC.gov

Nemiroff Alex

General Counsel and Secretary

Other

Date

Jan 12

Shares

768

Price

$275.74

Value

$212K

View Form 4 on SEC.gov

Kelly Timothy Edwin

CFO

Other

Date

Jan 12

Shares

943

Price

$275.74

Value

$260K

View Form 4 on SEC.gov

Mastrocola Lauren

PAO

Award

Date

Jan 8

Shares

3,750

Price

Value

View Form 4 on SEC.gov

Mastrocola Lauren

PAO

Other

Date

Jan 10

Shares

367

Price

$288.45

Value

$106K

View Form 4 on SEC.gov

Sniecinski Megan

COO

Award

Date

Jan 8

Shares

9,625

Price

Value

View Form 4 on SEC.gov

Sniecinski Megan

COO

Other

Date

Jan 10

Shares

1,087

Price

$288.45

Value

$314K

View Form 4 on SEC.gov

Nemiroff Alex

General Counsel and Secretary

Award

Date

Jan 8

Shares

6,875

Price

Value

View Form 4 on SEC.gov

Nemiroff Alex

General Counsel and Secretary

Other

Date

Jan 10

Shares

917

Price

$288.45

Value

$265K

View Form 4 on SEC.gov

Kelly Timothy Edwin

CFO

Award

Date

Jan 8

Shares

8,800

Price

Value

View Form 4 on SEC.gov

Kelly Timothy Edwin

CFO

Other

Date

Jan 10

Shares

1,335

Price

$288.45

Value

$385K

View Form 4 on SEC.gov

Souza Marcio

CEO · Director

Award

Date

Jan 8

Shares

27,640

Price

Value

View Form 4 on SEC.gov

Souza Marcio

CEO · Director

Other

Date

Jan 10

Shares

4,252

Price

$288.45

Value

$1.23M ⚡

View Form 4 on SEC.gov

Mastrocola Lauren

PAO

Other

Date

Jan 7

Shares

35

Price

$292.63

Value

$10K

View Form 4 on SEC.gov

Nemiroff Alex

General Counsel and Secretary

Other

Date

Jan 7

Shares

89

Price

$292.63

Value

$26K

View Form 4 on SEC.gov

⚡ = value ≥ $1M · Award/Option price shows — · formType=4 · securityName=Common Stock · url → sec.gov/Archives/edgar

1 / 3

Source: SEC EDGAR · Form 4 filings · ⚡ = value ≥ $1M · Award/Option price shows —

About PRAX insider trading

PRAX insider trades

Praxis Precision Medicines, Inc. (PRAX) insider trading data is sourced from SEC Form 4 filings submitted by corporate insiders, including Mastrocola Lauren (PAO), Nemiroff Alex (General Counsel and Secretary), Adage Capital Management, L.P. (10 percent owner). Over the past 12 months, 5 insiders have filed transactions with the SEC. PRAX insiders have been primarily selling, which may reflect pre-scheduled Rule 10b5-1 plan executions.

For Praxis Precision Medicines, Inc.'s institutional ownership breakdown and insider ownership percentage, see the Ownership tab → Ownership tab →

Buy/Sell signal logic
acquisitionOrDisposition field:
A = Acquisition (buy) · D = Disposition (sell)
RSU vesting (M-Exempt) excluded from sentiment
Form 4SEC filing required within 2 business days of any insider transaction
10b5-1Pre-scheduled trading plan that allows insiders to sell on autopilot
Open MktDirect purchase or sale on the open market (excludes awards, options)

Frequently asked questions

PRAX insider trading · 5 questions

The insiders of Praxis Precision Medicines, Inc. (PRAX) include executives and directors such as Mastrocola Lauren (PAO), Nemiroff Alex (General Counsel and Secretary), Adage Capital Management, L.P. (10 percent owner), among others. Over the past 12 months, 5 insiders have filed Form 4 transactions with the SEC. Insider transactions are required to be reported within 2 business days of the trade date.

PRAX board member insider tradingwho are PRAX insidersPRAX insider rosterPraxis Precision Medicines, Inc. executives insider activity

Source: FMP /stable/insider-trading/search · SEC EDGAR Form 3 & 4 · acquisitionOrDisposition A=Buy, D=Sell · RSU vesting (M-Exempt) excluded from sentiment bar · As of Jun 8, 2026