Companies: 10,795·Total market cap: $144.5T
Prothena Corporation plc

Prothena Corporation plc

PRTANASDAQHealthcare● Active
$8.56
$-0.23(-2.62%)
Market Cap$448143709
P/E Ratio
52W High$11.8
52W Low$4.76

Prothena Corporation plc (PRTA) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · PRTA · as of Sep 30, 2025

Ownership Breakdown

Institutions 81.45%
Insiders 11.69%
Public 6.87%

201

Institutional Holders

▼ 1 vs Q2

$416.06M

Total Inst. Value

▲ $162.45M vs Q2

52.35M

Shares Outstanding

freeFloat 88.31%

42.64M

13F Shares Held

▲ 863,034 vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

PRTA largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

FMR LLC

pharmaceutical preparations

7.90M14.68%

14.68%

$77.12BNov 13, 2025— held

BLACKROCK, INC.

pharmaceutical preparations

3.60M6.69%

6.69%

$35.12BNov 12, 2025 341.0K

VANGUARD GROUP INC

pharmaceutical preparations

2.05M3.81%

3.81%

$20.01BNov 7, 2025 126.4K

ARMISTICE CAPITAL, LLC

pharmaceutical preparations

1.82M3.39%

3.39%

$17.80BNov 17, 2025 412.0K

RUBRIC CAPITAL MANAGEMENT LP

pharmaceutical preparations

1.54M2.86%

2.86%

$15.03BNov 14, 2025NEW

ADAR1 CAPITAL MANAGEMENT, LLC

pharmaceutical preparations

1.47M2.73%

2.73%

$14.34BNov 14, 2025 1.91M

PALO ALTO INVESTORS LP

pharmaceutical preparations

1.32M2.46%

2.46%

$12.92BNov 14, 2025 49.3K

D. E. SHAW & CO., INC.

pharmaceutical preparations

1.32M2.44%

2.44%

$12.84BNov 14, 2025 923.9K

ACADIAN ASSET MANAGEMENT LLC

pharmaceutical preparations

1.24M2.30%

2.30%

$12.09BNov 13, 2025 221.1K

GEODE CAPITAL MANAGEMENT, LLC

pharmaceutical preparations

1.02M1.89%

1.89%

$9.95BNov 12, 2025 86.0K

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBullish — more buying than selling

28

Increased

+6.15M shares

5

New Positions

first time holders

16

Decreased

−5.19M shares

0

Sold Out

fully exited

Net shares change (top 50)

+963.4K

+6.15M / −5.19M

Net new holders

+17

5 new / 0 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

PRTA insider trading · insider activity

Source: SEC Form 4

Buy 100%Active transactions only0% Sell

Insiders have been net buyers of shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

10

Buy transactions

0

Sell transactions

0.00

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

SCULLY WILLIAM P

10 percent owner

Jun 4, 2026Purchase50,000$9.31$465.3K936.0KForm 4 ↗

SCULLY WILLIAM P

10 percent owner

Jun 2, 2026Purchase50,000$9.43$471.3K886.0KForm 4 ↗

SCULLY WILLIAM P

10 percent owner

May 22, 2026Purchase100,000$9.81$981.3K836.0KForm 4 ↗

WELCH DANIEL G

director

May 15, 2026Award27,000$9.76$263.5K27.0KForm 4 ↗

Selkoe Dennis J.

director

May 15, 2026Award27,000$9.76$263.5K27.0KForm 4 ↗

Ekman Lars

director

May 15, 2026Award27,000$9.76$263.5K27.0KForm 4 ↗

Dunn William H. Jr.

director

May 15, 2026Award27,000$9.76$263.5K27.0KForm 4 ↗

Cooke Shane

director

May 15, 2026Award27,000$9.76$263.5K27.0KForm 4 ↗

COLLIER RICHARD T

director

May 15, 2026Award27,000$9.76$263.5K27.0KForm 4 ↗

Kingston Anne Evans

Chief Strategy Officer

Apr 10, 2026Award100,000$10.50$1.05M100.0KForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

Prothena Corporation plc (PRTA) is primarily owned by institutional investors, who hold approximately 81.5% of total shares outstanding. Company insiders own approximately 11.69%, while retail and public investors account for the remaining 6.87%.

The largest institutional shareholder of Prothena Corporation plc is FMR LLC, holding approximately 7.90 million shares — equal to 14.68% of outstanding shares — as of September 30, 2025.

A total of 201 institutional investors currently hold PRTA stock, with a combined institutional value of approximately $416,062,605 as of the most recent 13F filing period.

Frequently asked questions

PRTA ownership

Prothena Corporation plc (PRTA) is primarily owned by institutional investors, who hold approximately 81.5% of shares. The largest shareholder is FMR LLC with a 14.68% stake. Company insiders hold 11.69%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns PRTA stockPRTA ownership structureSEC Form 13F institutional holdingsPRTA float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025