Companies: 10,795·Total market cap: $144.5T
Pyxis Oncology, Inc.

Pyxis Oncology, Inc.

PYXSNASDAQHealthcare● Active
$1.69
$-0.09(-5.06%)
Market Cap$107070761
P/E Ratio
52W High$5.55
52W Low$0.97

Pyxis Oncology, Inc. (PYXS) Insider Trading

Form 4 buy vs sell counts, ratio, and sentiment — switch this quarter or last 12 months; chart and transactions below.

SEC EDGAR · FMP · PYXS · as of Jun 8, 2026

Activity summary

Buy transactions

2

P-Purchase only

Sell transactions

3

12 Months

Buy/Sell ratio

0.67

Buy/Sell (by trades)

Overall sentiment

BEARISH
↑ Buy 40%Active transactions only · RSU vesting excluded60% Sell ↓

Pyxis Oncology, Inc. insiders have been primarily selling shares over the past 12 Months. Selling activity is often driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment toward the company.

Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · Buy = P-Purchase only · Sell = S-Sale only

As of Jun 8, 2026

PYXS insider buying and selling by quarter

PYXS insider selling · PYXS insider buying stocks · quarterly insider activity

Total insider buying (incl. awards)Total insider selling
1.9M946K0
2024 Q4
2025 Q1
2025 Q2
2026 Q1

Mobile shows last 4Q · Desktop shows full 8Q

Source: SEC EDGAR · Form 3 & 4 · via Financial Modeling Prep · last 8 quarters

As of Jun 8, 2026

Active insiders

Most active in past 12 months · PYXS ceo insider trading

Showing all insiders · Click a card to filter the transactions table below

Aggregated from reportingName · top 5 by trade count (12M) · no extra API

Recent insider transactions

PYXS executive sell shares · PYXS board member insider trading · PYXS insider trading SEC filing

Showing 45 most recent · Common Stock · Form 4 only

Scroll horizontally to see all columns

Wadhane Jitendra

Prin Fin & Acct Officer

Award

Date

Mar 24

Shares

109,461

Price

Value

View Form 4 on SEC.gov

HUMPHREY RACHEL

Director

Sale

Date

Apr 14

Shares

1,400

Price

$0.97

Value

$1K

View Form 4 on SEC.gov

HUMPHREY RACHEL

Director

Sale

Date

Apr 17

Shares

200

Price

$0.97

Value

$194

View Form 4 on SEC.gov

HUMPHREY RACHEL

Director

Sale

Date

Apr 21

Shares

13,896

Price

$1.03

Value

$14K

View Form 4 on SEC.gov

Connealy Pamela Ann

CFO & COO

Purchase

Date

Nov 26

Shares

83,400

Price

$1.96

Value

$163K

View Form 4 on SEC.gov

Connealy Pamela Ann

CFO & COO

Purchase

Date

Nov 26

Shares

5,450

Price

$2.00

Value

$11K

View Form 4 on SEC.gov

Palani Santhosh

Director

Award

Date

Jun 7

Shares

6,000

Price

Value

View Form 4 on SEC.gov

Connealy Pamela Ann

CFO & COO

Award

Date

Mar 26

Shares

328,710

Price

Value

View Form 4 on SEC.gov

FLAVIN JOHN L

Director

Award

Date

Mar 26

Shares

35,219

Price

Value

View Form 4 on SEC.gov

Cline Darren S

Director

Award

Date

Mar 26

Shares

35,219

Price

Value

View Form 4 on SEC.gov

Lewis-Hall Freda C

Director

Award

Date

Mar 26

Shares

35,219

Price

Value

View Form 4 on SEC.gov

Dupont Jakob

Director

Award

Date

Mar 26

Shares

38,741

Price

Value

View Form 4 on SEC.gov

HUMPHREY RACHEL

Director

Award

Date

Mar 26

Shares

38,741

Price

Value

View Form 4 on SEC.gov

Wadhane Jitendra

SVP, Chief Accounting Officer

Award

Date

Mar 26

Shares

131,484

Price

Value

View Form 4 on SEC.gov

Connealy Pamela Ann

CFO and COO

Other

Date

Nov 29

Shares

36,949

Price

$1.40

Value

$52K

View Form 4 on SEC.gov

Wadhane Jitendra

CAO

Award

Date

Nov 15

Shares

40,000

Price

Value

View Form 4 on SEC.gov

Connealy Pamela Ann

CFO and COO

Purchase

Date

Sep 28

Shares

8,000

Price

$1.87

Value

$15K

View Form 4 on SEC.gov

Wadhane Jitendra

CAO

Purchase

Date

Sep 27

Shares

2,500

Price

$1.87

Value

$5K

View Form 4 on SEC.gov

Connealy Pamela Ann

CFO and COO

Purchase

Date

Sep 27

Shares

6,426

Price

$1.85

Value

$12K

View Form 4 on SEC.gov

Wadhane Jitendra

CAO

Purchase

Date

Sep 25

Shares

5,000

Price

$1.77

Value

$9K

View Form 4 on SEC.gov

Connealy Pamela Ann

CFO and COO

Purchase

Date

Sep 25

Shares

12,000

Price

$1.67

Value

$20K

View Form 4 on SEC.gov

Wadhane Jitendra

CAO

Purchase

Date

Sep 22

Shares

2,500

Price

$1.74

Value

$4K

View Form 4 on SEC.gov

Connealy Pamela Ann

CFO and COO

Purchase

Date

Sep 22

Shares

5,000

Price

$1.74

Value

$9K

View Form 4 on SEC.gov

Sullivan Lara

President and CEO · Director

Sale

Date

Sep 14

Shares

100

Price

$2.25

Value

$225

View Form 4 on SEC.gov

Sullivan Lara

President and CEO · Director

Sale

Date

Sep 18

Shares

8,541

Price

$2.10

Value

$18K

View Form 4 on SEC.gov

⚡ = value ≥ $1M · Award/Option price shows — · formType=4 · securityName=Common Stock · url → sec.gov/Archives/edgar

1 / 2

Source: SEC EDGAR · Form 4 filings · ⚡ = value ≥ $1M · Award/Option price shows —

About PYXS insider trading

PYXS insider trades

Pyxis Oncology, Inc. (PYXS) insider trading data is sourced from SEC Form 4 filings submitted by corporate insiders, including Wadhane Jitendra (Prin Fin & Acct Officer). Over the past 12 months, 1 insiders have filed transactions with the SEC. PYXS insiders have been primarily selling, which may reflect pre-scheduled Rule 10b5-1 plan executions.

For Pyxis Oncology, Inc.'s institutional ownership breakdown and insider ownership percentage, see the Ownership tab → Ownership tab →

Buy/Sell signal logic
acquisitionOrDisposition field:
A = Acquisition (buy) · D = Disposition (sell)
RSU vesting (M-Exempt) excluded from sentiment
Form 4SEC filing required within 2 business days of any insider transaction
10b5-1Pre-scheduled trading plan that allows insiders to sell on autopilot
Open MktDirect purchase or sale on the open market (excludes awards, options)

Frequently asked questions

PYXS insider trading · 5 questions

The insiders of Pyxis Oncology, Inc. (PYXS) include executives and directors such as Wadhane Jitendra (Prin Fin & Acct Officer), among others. Over the past 12 months, 1 insiders have filed Form 4 transactions with the SEC. Insider transactions are required to be reported within 2 business days of the trade date.

PYXS board member insider tradingwho are PYXS insidersPYXS insider rosterPyxis Oncology, Inc. executives insider activity

Source: FMP /stable/insider-trading/search · SEC EDGAR Form 3 & 4 · acquisitionOrDisposition A=Buy, D=Sell · RSU vesting (M-Exempt) excluded from sentiment bar · As of Jun 8, 2026