Companies: 10,795·Total market cap: $144.5T
Septerna, Inc.

Septerna, Inc.

SEPNNASDAQHealthcare● Active
$30.93
$-0.22(-0.71%)
Market Cap$1.4B
P/E Ratio
52W High$32.63
52W Low$9.7

Septerna, Inc. (SEPN) Earnings: Dates, EPS & Revenue History

Quarterly EPS vs. estimates, revenue surprises, next earnings date, and analyst consensus.

SEPN · earnings · updated Jun 8, 2026

Latest Earnings

Q2 FY2026
EPS Actual
-$0.19
Est. -$0.51 · +62.8%
Revenue
$0.03B
Est. $0.02B · +56.3%
Fiscal Period
Q2 FY2026
FY ends December
Report Date
May 12, 2026
After Market Close
Beat EPSBeat Revenue 1-Quarter EPS Beat Streak
SEPN reports quarterly as a NASDAQ-listed Biotechnology company. Fiscal year ends in December. Data: FMP · Updated hourly.

Next Earnings Date

Days Away85
Expected DateSep 1, 2026
Fiscal PeriodQ3 FY2026
Release TimeTime TBD (Unconfirmed)
EPS Est.$1.19
Rev. Est.$0.35B

EPS & Revenue vs. Estimates

Actual (Beat)
Actual (Miss)
Estimated

Earnings History

Q3 FY2026
Aug 10, 2026
EPS Actual
EPS Est.
-$0.42
EPS Surpr.
Revenue
Q2 FY2026
May 12, 2026Beat
EPS Actual
-$0.19
EPS Est.
-$0.51
EPS Surpr.
+62.8%
Revenue
$0.03B
Q1 FY2026
Mar 9, 2026Miss
EPS Actual
-$0.24
EPS Est.
-$0.23
EPS Surpr.
-4.3%
Revenue
$0.02B
Q4 FY2025
Nov 10, 2025Miss
EPS Actual
-$0.09
EPS Est.
$0.19
EPS Surpr.
-147.4%
Revenue
$0.02B
Q3 FY2025
Aug 11, 2025Miss
EPS Actual
-$0.56
EPS Est.
-$0.05
EPS Surpr.
-1020.0%
Revenue
$0.00B
Q2 FY2025
May 15, 2025Miss
EPS Actual
-$0.49
EPS Est.
-$0.38
EPS Surpr.
-28.9%
Revenue
$0.00B
Q1 FY2025
Mar 27, 2025Beat
EPS Actual
-$0.64
EPS Est.
-$0.69
EPS Surpr.
+7.3%
Revenue
$0.00B
Q4 FY2024
Nov 21, 2024Miss
EPS Actual
-$8.40
EPS Est.
-$0.83
EPS Surpr.
-912.0%
Revenue
$0.00B

Analyst Estimates

Limited analyst coverage (fewer than 3 analysts). Estimates may not reflect market consensus.
EPS Estimates
PeriodLowConsensusHigh# Analysts
Q4 FY2027$-1.48$-0.92$-0.371
Q3 FY2027$-1.44$-0.90$-0.361
Q2 FY2027$-1.30$-0.81$-0.331
Q1 FY2027$-1.31$-0.81$-0.331
Q4 FY2026$-0.80$-0.50$-0.201
Q3 FY2026$-0.75$-0.49$-0.185
Revenue Estimates
PeriodLowConsensusHigh# Analysts
Q4 FY2027$0.0B$0.0B$0.0B3
Q3 FY2027$0.0B$0.0B$0.0B3
Q2 FY2027$0.0B$0.0B$0.0B3
Q1 FY2027$0.0B$0.0B$0.0B3
Q4 FY2026$0.0B$0.0B$0.0B5
Q3 FY2026$0.0B$0.0B$0.0B6

Earnings Price Reaction

Closing price one trading day before vs. one trading day after each earnings release.
Q2 FY2026+5.39%
Report Date
May 12, 2026
EPS Beat/Miss
+62.8%
Price Before
$23.57
Price After
$24.84
Q1 FY2026+0.97%
Report Date
Mar 9, 2026
EPS Beat/Miss
-4.3%
Price Before
$28.78
Price After
$29.06
Q4 FY2025-2.22%
Report Date
Nov 10, 2025
EPS Beat/Miss
-147.4%
Price Before
$18.51
Price After
$18.10
Q3 FY2025-1.71%
Report Date
Aug 11, 2025
EPS Beat/Miss
-1020.0%
Price Before
$11.69
Price After
$11.49
Q2 FY2025-0.39%
Report Date
May 15, 2025
EPS Beat/Miss
-28.9%
Price Before
$10.16
Price After
$10.12
Q1 FY2025+2.44%
Report Date
Mar 27, 2025
EPS Beat/Miss
+7.3%
Price Before
$6.14
Price After
$6.29
Q4 FY2024-3.16%
Report Date
Nov 21, 2024
EPS Beat/Miss
-912.0%
Price Before
$22.50
Price After
$21.79
Q4 FY2023
Report Date
Dec 31, 2023
EPS Beat/Miss
Price Before
Price After
$21.40
Avg Beat Reaction+3.92%
Avg Miss Reaction-1.30%
Beat Rate2 / 8 quarters
Largest Move+5.39% (Q2 FY2026)
Data: FMP /historical-price-eod/full · field: close

About Earnings & Data Methodology

Data source: Financial Modeling Prep (FMP)  |  Updated: Hourly  |  Surprise%: (Actual − Estimate) / |Estimate| × 100  |  Fiscal year: SEPN ends December

Septerna, Inc. (SEPN) most recently reported earnings on May 12, 2026 for Q2 FY2026, posting EPS of $-0.19 — beating the analyst consensus of $-0.51 by +62.8%. The next SEPN earnings date is expected around September 1, 2026.

Each quarter, investors track SEPN earnings for signals on forward guidance and business momentum. For longer-term revenue trends, see the Revenue tab. SEPN revenue tab →

Earnings Glossary
EPS (Earnings Per Share)
Net income ÷ diluted shares outstanding. The primary metric analysts use to gauge quarterly profitability.
Earnings Surprise %
(Actual − Estimate) / |Estimate| × 100. Positive = Beat. Negative = Miss.
Beat / Miss / In-Line
Beat = Actual ≥ Estimate. Miss = Actual < Estimate. In-Line = within ±1%.
BMO / AMC
Before Market Open / After Market Close. Two windows when companies typically release results.
Fiscal Quarter
SEPN's fiscal year ends in December. Fiscal quarters may not align with calendar quarters.
Analyst Consensus
Average EPS/Revenue forecast across all covering analysts. More analysts = more reliable estimate.
Figures tie to FMP earnings calendar, estimates, and SEC 10-Q/10-K filings where noted.

Frequently asked questions

SEPN earnings · 5 questions

Septerna, Inc.'s next earnings report is expected around September 1, 2026. SEPN typically reports quarterly — approximately every three months. The exact date is confirmed by the company 2–4 weeks before the release. Time is currently TBD; SEPN historically reports after market close (AMC).

SEPN earnings datewhen is SEPN earningsSEPN next earnings datewhen does SEPN report earningsSEPN earnings calendar

Source: FMP · Septerna, Inc. SEC filings · US GAAP · Septerna, Inc. SEC 10-K & 10-Q filings · US GAAP · Updated: Jun 8, 2026