Companies: 10,795·Total market cap: $144.5T

Sionna Therapeutics, Inc.

Sionna Therapeutics, Inc.

SIONNASDAQHealthcare● Active

$33.51

$-1.86(-5.26%)

Market Cap$1.5B

P/E Ratio—

52W High$48.445

52W Low$13.51

Avg Volume392K

Open$35.29

Beta1.29

Net Income Financials Revenue

Sionna Therapeutics, Inc. (SION) Net Income & Profit History

Annual & trailing net income, net margin, YoY change, and peer profitability context.

SION · net income · updated Jun 8, 2026

Core profitability metrics

SION · net income · margin · TTM · CAGR

Net income was −$75.3M for FY2025 (fiscal year ending 2025-12-31), down 22.0% year-over-year. Net profit margin was —.

FY2025 Net Income−$75.3M▼ -22.0% YoY

Trailing 12M (TTM)−$85.6Mtrailing 4 quarters sum

Net Profit Margin——

YoY Change-22.0%—

5-Year CAGRN/AN/A — contains loss years

FormulaNet Margin = Net Income ÷ Revenue × 100TTM = trailing 4 quarters sumCAGR → N/A if either endpoint ≤ 0

Source: FMP /income-statement · US GAAP · USDUpdated: Jun 8, 2026

Annual net income history

Net Income (bars) · Net Profit Margin % (line)

Net IncomeNet LossNet Margin %

▸ FMP /income-statement · Annual · SION net income history · SION profit margin

Annual net income data

SION · net income history · annual / quarterly

Fiscal YearNet IncomeYoY ChangeNet MarginRevenue

FY2025Loss−$75.3M▼ 22.0%—$0

FY2024Loss−$61.7M▼ 30.5%—$0

FY2023Loss−$47.3M▼ 17.5%—$0

FY2022Loss−$40.2M——$0

Net income vs peers (Healthcare)

SION vs peers · net income

#CompanyNet IncomeYoYNet MarginRelative

#1

Sionna Therapeutics, Inc.YOU

SION

−$75.3M-22.0%—

Loss

Johnson & Johnson

$26.80B+90.6%28.5%

Eli Lilly and Company

$20.64B+94.9%31.7%

UnitedHealth Group Incorporated

$12.06B-16.3%2.7%

$4.23B-1.2%6.9%

Healthcare · Sorted by Net Income · FMP /income-statementFull Net Income Rankings →

About Net Income & Methodology

Sionna Therapeutics, Inc. (SION) reported net income of −$75.3M for FY2025 (fiscal year ending 2025-12-31), down 22.0% year-over-year. The net profit margin was — — meaning the company kept $— of every dollar of revenue as profit.

Sionna Therapeutics, Inc. has not yet achieved annual profitability based on available data (4 fiscal years). The company has reported net losses across all available periods.

Sionna Therapeutics, Inc.'s net profit margin was — for FY2025, based on the latest annual results.

Investors sometimes search for "Sionna Therapeutics, Inc. net worth" — the company's market capitalization is a separate figure from SION net income. Data sourced from FMP /income-statement · US GAAP · USD.

Figures tie to SEC 10-K/10-Q and FMP /income-statement where noted.

Revenue Financial statements Earnings Forecast Price history Market cap Free cash flow

Frequently asked questions

SION net income · 4 questions

Sionna Therapeutics, Inc. is not currently profitable on an annual basis. The company reported a net loss of $75.3M for FY2025.

is SION profitabledoes SION make a profitSION profitabilitySION profitable company

▸ Source: FMP /income-statement · GAAP · Sionna Therapeutics, Inc. · Sionna Therapeutics, Inc. SEC 10-K & 10-Q filings · US GAAP · Last updated: Jun 8, 2026