Companies: 10,795·Total market cap: $144.5T
SOPHiA GENETICS S.A.

SOPHiA GENETICS S.A.

SOPHNASDAQHealthcare● Active
$5.28
+$0.28(+5.60%)
Market Cap$378410736
P/E Ratio
52W High$5.7
52W Low$2.59

SOPHiA GENETICS S.A. (SOPH) Stock Ownership

Institutional vs insider vs public ownership from 13F and float data — top holders, activity, and insider trades below.

SEC 13F · FMP · SOPH · as of Sep 30, 2025

Ownership Breakdown

Institutions 24.71%
Insiders 27.84%
Public 47.45%

40

Institutional Holders

▲ 8 vs Q2

$84.31M

Total Inst. Value

▲ $33.08M vs Q2

71.67M

Shares Outstanding

freeFloat 72.16%

17.71M

13F Shares Held

▲ 1.19M vs Q2

Institutional ownership = 13F shares ÷ total outstanding. Insider % = 100 − free float. Public % = free float − institution %. Data: FMP /symbol-positions-summary + /shares-float + SEC EDGAR.

Top Institutional Holders

SOPH largest shareholders · institutional ownership

Q3 2025 · SEC 13F

Showing top 10 holders

HolderShares% OwnedWeightValueReportedChange

GENERATION INVESTMENT MANAGEMENT LLP

biological products, (no diagnostic substances)

6.79M10.09%

10.09%

$32.32BNov 10, 2025— held

AKRE CAPITAL MANAGEMENT LLC

biological products, (no diagnostic substances)

3.72M5.52%

5.52%

$17.70BNov 13, 2025— held

BANQUE PICTET & CIE SA

biological products, (no diagnostic substances)

2.21M3.28%

3.28%

$10.51BOct 21, 2025— held

ALTA WEALTH ADVISORS LLC

biological products, (no diagnostic substances)

1.41M2.09%

2.09%

$6.71BNov 3, 2025 1.41M

PRINCIPAL FINANCIAL GROUP INC

biological products, (no diagnostic substances)

1.39M2.07%

2.07%

$6.62BNov 4, 2025 9.0K

ARCHON CAPITAL MANAGEMENT LLC

biological products, (no diagnostic substances)

427.1K63.44%

63.44%

$2.03BNov 14, 2025 105.5K

PICTET & CIE (EUROPE) SA

biological products, (no diagnostic substances)

255.2K37.91%

37.91%

$1.21BOct 21, 2025— held

MILLENNIUM MANAGEMENT LLC

biological products, (no diagnostic substances)

225.9K33.56%

33.56%

$1.08BNov 14, 2025 358.5K

FEDERATED HERMES, INC.

biological products, (no diagnostic substances)

210.0K31.19%

31.19%

$999.60MNov 3, 2025 10.0K

EDMOND DE ROTHSCHILD HOLDING S.A.

biological products, (no diagnostic substances)

203.3K30.20%

30.20%

$967.87MNov 13, 2025— held

Data from SEC Form 13F filings. Ownership bar normalised to largest holder. Change flags: isNew / isSoldOut / changeInSharesNumber (FMP extract-analytics/holder).

Institutional Activity

Q3 2025 vs prior quarter

Q3 2025

Net institutional sentimentBullish — more buying than selling

13

Increased

+1.60M shares

9

New Positions

first time holders

8

Decreased

−464.6K shares

3

Sold Out

fully exited

Net shares change (top 50)

+1.14M

+1.60M / −464.6K

Net new holders

+11

9 new / 3 exited

Based on top 50 institutional holders by position size. Fields: isNew, isSoldOut, changeInSharesNumber (FMP extract-analytics/holder, limit=50).

Insider Buying vs Selling

SOPH insider trading · insider activity

Source: SEC Form 4

Buy 5%Active transactions only95% Sell

Insiders have been primarily selling shares recently. Selling may be driven by pre-scheduled Rule 10b5-1 plans rather than negative sentiment.

28

Buy transactions

68

Sell transactions

0.41

Buy/Sell ratio

$0M

Total disposed

Recent Insider Transactions

Showing 10 most recent · Common Stock only

Name · RoleDateTypeSharesPriceValueAfter Trans.Filing

CARDOZA GEORGE

Chief Financial Officer

Jun 5, 2026Purchase20,000$4.95$99.0K311.5KForm 4 ↗

Menu Philippe

Chief Medical Officer

May 26, 2026Sale5,000$4.95$24.8K250.8KForm 4 ↗

Muken Ross

President

May 19, 2026Sale761$4.60$3.5K680.9KForm 4 ↗

Xu Zhenyu

Chief Scientific Officer

May 19, 2026Sale608$4.60$2.8K626.3KForm 4 ↗

Camblong Jurgi

Chief Executive Officer

May 19, 2026Sale4,486$4.60$20.7K3.63MForm 4 ↗

Menu Philippe

Chief Medical Officer

May 19, 2026Sale608$4.61$2.8K255.8KForm 4 ↗

Van Well Daan

Chief Legal Officer

May 19, 2026Sale684$4.60$3.1K345.1KForm 4 ↗

Valente Manuela

Chief People Officer

May 19, 2026Sale380$4.60$1.7K214.7KForm 4 ↗

Puylaert Kevin

Chief Sales Officer

May 19, 2026Sale33$4.54$149.899148.2KForm 4 ↗

Xu Zhenyu

Chief Scientific Officer

May 13, 2026Sale4,000$4.54$18.2K626.9KForm 4 ↗

Source: /insider-trading/search (FMP stable). Buy/Sell direction: acquisitionOrDisposition A=Buy, D=Sell. RSU vesting (M-Exempt) excluded from sentiment bar. All data from SEC EDGAR public filings.

About institutional & insider ownership

SOPHiA GENETICS S.A. (SOPH) is primarily owned by institutional investors, who hold approximately 24.7% of total shares outstanding. Company insiders own approximately 27.84%, while retail and public investors account for the remaining 47.45%.

The largest institutional shareholder of SOPHiA GENETICS S.A. is GENERATION INVESTMENT MANAGEMENT LLP, holding approximately 6.79 million shares — equal to 10.09% of outstanding shares — as of September 30, 2025.

A total of 40 institutional investors currently hold SOPH stock, with a combined institutional value of approximately $84,309,953 as of the most recent 13F filing period.

Frequently asked questions

SOPH ownership

SOPHiA GENETICS S.A. (SOPH) is primarily owned by institutional investors, who hold approximately 24.7% of shares. The largest shareholder is GENERATION INVESTMENT MANAGEMENT LLP with a 10.09% stake. Company insiders hold 27.84%. Data sourced from SEC Form 13F as of September 30, 2025.

who owns SOPH stockSOPH ownership structureSEC Form 13F institutional holdingsSOPH float vs institutions
Source: FMP · SEC Form 13F · SEC Form 4As of September 30, 2025